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Gene Expression Data
Assay Details
Assay
Reference: J:213586 Jackson A, et al., Endoderm-specific deletion of Tbx1 reveals an FGF-independent role for Tbx1 in pharyngeal apparatus morphogenesis. Dev Dyn. 2014 Sep;243(9):1143-51
Assay type: RNA in situ
MGI Accession ID: MGI:7514574
Gene symbol: Pax1
Gene name: paired box 1
Probe: Pax1 probe3
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1D,D': embryonic day 10.5; Tbx1tm2.1Bem/? (more )
Structure Level Pattern Image Note
TS17: 1st branchial pouch Present 1D' , 1D Expression in pouches 1-3.
TS17: 2nd branchial pouch Present 1D' , 1D Expression in pouches 1-3.
TS17: 3rd branchial pouch Present 1D' , 1D Expression in pouches 1-3.
Specimen 1E,E': embryonic day 10.5; Sox17tm2.1(icre)Heli/Sox17+, Tbx1tm2.1Bem/Tbx1tm2.1Bem (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 1st branchial pouch Present 1E , 1E'
Specimen 3F: embryonic day 10.5; Tbx1tm2.1Bem/? (more )
Structure Level Pattern Image Note
TS17: 1st branchial pouch Present 3F
TS17: 2nd branchial pouch Present 3F
TS17: 3rd branchial pouch Present 3F
Specimen 3G: embryonic day 10.5; Fgf8tm2Mrc/Fgf8tm2Mrc, Sox17tm2.1(icre)Heli/Sox17+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 1st branchial pouch Present 3G Authors report all pouches are present in the mutant.
TS17: 2nd branchial pouch Present 3G Authors report all pouches are present in the mutant.
TS17: 3rd branchial pouch Present 3G Authors report all pouches are present in the mutant.
Specimen 4A: embryonic day 10.5; Tbx1tm2.1Bem/? (more )
Structure Level Pattern Image Note
TS17: 2nd branchial arch Present 4A
Specimen 4B: embryonic day 10.5; Fgf3tm1.2Sms/Fgf3+, Fgf8tm2Mrc/Fgf8+, Sox17tm2.1(icre)Heli/Sox17+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 2nd branchial arch Present 4B Authors report 2nd arch is normal-sized compared to control.
Specimen 4C: embryonic day 10.5; Fgf3tm1.1Sms/Fgf3tm1.2Sms, Fgf8tm2Mrc/Fgf8+, Sox17tm2.1(icre)Heli/Sox17+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 2nd branchial arch Present 4C Authors report 2nd arch and 3rd pouch hypoplasia
TS17: 3rd branchial pouch Present 4C Authors report 2nd arch and 3rd pouch hypoplasia
Specimen 4D: embryonic day 10.5; Fgf3tm1.2Sms/Fgf3+, Fgf8tm1.4Mrt/Fgf8tm2Mrc, Sox17tm2.1(icre)Heli/Sox17+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 2nd branchial arch Present 4D Authors report 2nd arch and 3rd pouch hypoplasia
TS17: 3rd branchial pouch Present 4D Authors report 2nd arch and 3rd pouch hypoplasia
Specimen 4E: embryonic day 10.5; Fgf3tm1.1Sms/Fgf3tm1.2Sms, Fgf8tm1.4Mrt/Fgf8tm2Mrc, Sox17tm2.1(icre)Heli/Sox17+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 2nd branchial arch Present 4E Authors report 2nd arch and 3rd pouch hypoplasia
TS17: 3rd branchial pouch Present 4E Authors report 2nd arch and 3rd pouch hypoplasia
Specimen 4F: embryonic day 10.0; Tbx1tm2.1Bem/? (more )
Structure Level Pattern Image Note
TS16: branchial arch Present 4F
Specimen 4G: embryonic day 10.0; Fgfr1tm3.2Cxd/Fgfr1tm3.2Cxd, Fgfr2tm1Dor/Fgfr2tm1Dor, Sox17tm2.1(icre)Heli/Sox17+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS16: branchial arch Present 4G Authors report pharyngeal phenotype identical to Fgf3;8cko embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory