Phenotypes associated with this allele

• Allele Symbol: Ube2o⁺
• Allele Name: wild type
• Allele ID: MGI:3609341
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Ube2o^tm1.1(KOMP)Mbp/Ube2o^+	B6N(Cg)-Ube2o^tm1.1(KOMP)Mbp/J	MGI:5763856
cx2	Ube2o^tm1.1(KOMP)Mbp/Ube2o^+ Tg(MMTV-PyVT)634Mul/0	involves: C57BL/6 * C57BL/6N * FVB/N	MGI:5902964
cx3	Ube2o^tm1.1(KOMP)Mbp/Ube2o^+ Tg(TRAMP)8247Ng/0	involves: C57BL/6 * C57BL/6N * FVB/N	MGI:5902966

Genotype
MGI:5763856

ht1

• Allelic Composition: Ube2o^{tm1.1(KOMP)Mbp}/Ube2o⁺
• Genetic Background: B6N(Cg)-Ube2o^{tm1.1(KOMP)Mbp}/J
• Cell Lines: DEPD00564_2_D02

Data Sources

IMPC Data for Ube2o

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

increased grip strength ( J:211773 )

♂

IMPC - JAX

homeostasis/metabolism

increased circulating cholesterol level ( J:211773 )

♂

IMPC - JAX

increased circulating alanine transaminase level ( J:211773 )

♂

IMPC - JAX

Genotype
MGI:5902964

cx2

• Allelic Composition: Ube2o^{tm1.1(KOMP)Mbp}/Ube2o⁺; Tg(MMTV-PyVT)634Mul/0
• Genetic Background: involves: C57BL/6 * C57BL/6N * FVB/N

mortality/aging

increased tumor-free survival time ( J:239679 )

• mice exhibit extended survival compared with Tg(MMTV-PyVT)634Mul mice

neoplasm

decreased tumor growth/size ( J:239679 )

• reduced tumor size and weight of mammary glands compared with Tg(MMTV-PyVT)634Mul mice

increased tumor latency ( J:239679 )

• compared with Tg(MMTV-PyVT)634Mul mice

Genotype
MGI:5902966

cx3

• Allelic Composition: Ube2o^{tm1.1(KOMP)Mbp}/Ube2o⁺; Tg(TRAMP)8247Ng/0
• Genetic Background: involves: C57BL/6 * C57BL/6N * FVB/N

neoplasm

decreased tumor growth/size ( J:239679 )

• reduced tumor volume and weight compared with Tg(TRAMP)8247Ng mice