All Phenotypes Nxn<+> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Nxn⁺
wild type
MGI:2434317

Summary

14 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Nxn^em1(IMPC)J/Nxn⁺	C57BL/6NJ-Nxn^em1(IMPC)J/J	MGI:6263064
ht2	Nxn^em1(IMPC)Bay/Nxn⁺	C57BL/6N-Nxn^em1(IMPC)Bay/Bay	MGI:6288617
ht3	Nxn^em1(IMPC)Mbp/Nxn⁺	C57BL/6N-Nxn^em1(IMPC)Mbp/Ucd	MGI:7551182
ht4	Nxn^{tm1a(EUCOMM)Wtsi}/Nxn⁺	C57BL/6N-Nxn^{tm1a(EUCOMM)Wtsi}/Bay	MGI:5884019
ht5	Nxn^{tm1a(EUCOMM)Wtsi}/Nxn⁺	C57BL/6N-Nxn^{tm1a(EUCOMM)Wtsi}/Ieg	MGI:5782148
ht6	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Bay	MGI:5608339
ht7	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Ccpcz	MGI:6461492
ht8	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/H	MGI:5757444
ht9	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Ics	MGI:6263066
ht10	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/MbpMmucd	MGI:6325161
ht11	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Nju	MGI:6263067
ht12	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Rbrc	MGI:5757447
ht13	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Ucd	MGI:5757446
ht14	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Wtsi	MGI:5757443

Allelic Composition	Nxn^em1(IMPC)J/Nxn⁺
Genetic Background	C57BL/6NJ-Nxn^em1(IMPC)J/J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^em1(IMPC)J mutation (1 available); any Nxn mutation (498 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

increased mean corpuscular hemoglobin concentration ( J:211773 )

IMPC - JAX

homeostasis/metabolism

increased circulating bilirubin level ( J:211773 )

IMPC - JAX

increased fasting circulating glucose level ( J:211773 )

IMPC - JAX

Allelic Composition	Nxn^em1(IMPC)Bay/Nxn⁺
Genetic Background	C57BL/6N-Nxn^em1(IMPC)Bay/Bay

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^em1(IMPC)Bay mutation (1 available); any Nxn mutation (498 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

unresponsive to tactile stimuli ( J:211773 )

IMPC - BCM

cardiovascular system

abnormal retina blood vessel morphology ( J:211773 )

IMPC - BCM

homeostasis/metabolism

decreased circulating alkaline phosphatase level ( J:211773 )

IMPC - BCM

vision/eye

abnormal retina blood vessel morphology ( J:211773 )

IMPC - BCM

Allelic Composition	Nxn^em1(IMPC)Mbp/Nxn⁺
Genetic Background	C57BL/6N-Nxn^em1(IMPC)Mbp/Ucd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^em1(IMPC)Mbp mutation (0 available); any Nxn mutation (498 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

hemorrhage ( J:211773 )

IMPC - UCD

embryo

spina bifida ( J:211773 )

IMPC - UCD

growth/size/body

decreased body length ( J:211773 )

IMPC - UCD

nervous system

spina bifida ( J:211773 )

IMPC - UCD

Allelic Composition	Nxn^{tm1a(EUCOMM)Wtsi}/Nxn⁺
Genetic Background	C57BL/6N-Nxn^{tm1a(EUCOMM)Wtsi}/Bay
Cell Lines	EPD0045_1_A11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1a(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (498 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

decreased cardiac muscle contractility ( J:211773 )

IMPC - BCM

muscle

decreased cardiac muscle contractility ( J:211773 )

IMPC - BCM

vision/eye

irregularly shaped pupil ( J:211773 )

IMPC - BCM

anophthalmia ( J:211773 )

IMPC - BCM

Allelic Composition	Nxn^{tm1a(EUCOMM)Wtsi}/Nxn⁺
Genetic Background	C57BL/6N-Nxn^{tm1a(EUCOMM)Wtsi}/Ieg
Cell Lines	EPD0045_1_B11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1a(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (498 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

increased grip strength ( J:165965 )

IMPC - HMGU

Allelic Composition	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺
Genetic Background	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Bay
Cell Lines	EPD0045_1_A11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1b(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (498 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

unresponsive to tactile stimuli ( J:211773 )

IMPC - BCM

Allelic Composition	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺
Genetic Background	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Ccpcz
Cell Lines	EPD0045_1_B11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1b(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (498 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

endocrine/exocrine glands

abnormal mammary gland morphology ( J:211773 )

IMPC - CCP-IMG

hematopoietic system

increased effector memory CD8-positive, alpha-beta T cell number ( J:211773 )

IMPC - CCP-IMG

homeostasis/metabolism

increased circulating HDL cholesterol level ( J:211773 )

IMPC - CCP-IMG

increased circulating triglyceride level ( J:211773 )

IMPC - CCP-IMG

immune system

increased effector memory CD8-positive, alpha-beta T cell number ( J:211773 )

IMPC - CCP-IMG

integument

abnormal mammary gland morphology ( J:211773 )

IMPC - CCP-IMG

Allelic Composition	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺
Genetic Background	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/H
Cell Lines	EPD0045_1_B11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1b(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (498 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

craniofacial

abnormal snout morphology ( J:211773 )

IMPC - HAR

growth/size/body

abnormal snout morphology ( J:211773 )

IMPC - HAR

Allelic Composition	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺
Genetic Background	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Ics
Cell Lines	EPD0045_1_B11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1b(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (498 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

decreased exploration in new environment ( J:211773 )

IMPC - ICS

abnormal freezing behavior ( J:211773 )

IMPC - ICS

abnormal locomotor behavior ( J:211773 )

IMPC - ICS

decreased locomotor activity ( J:211773 )

IMPC - ICS

homeostasis/metabolism

increased circulating alkaline phosphatase level ( J:211773 )

IMPC - ICS

limbs/digits/tail

abnormal digit morphology ( J:211773 )

IMPC - ICS

Allelic Composition	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺
Genetic Background	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/MbpMmucd
Cell Lines	EPD0045_1_A11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1b(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (498 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

short tibia ( J:211773 )

IMPC - UCD

skeleton

short tibia ( J:211773 )

IMPC - UCD

Allelic Composition	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺
Genetic Background	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Nju
Cell Lines	EPD0045_1_A11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1b(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (498 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal optic disk morphology ( J:211773 )

IMPC - MARC

vision/eye

abnormal optic disk morphology ( J:211773 )

IMPC - MARC

Allelic Composition	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺
Genetic Background	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Rbrc
Cell Lines	EPD0045_1_A11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1b(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (498 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

short tibia ( J:211773 )

IMPC - RBRC

skeleton

short tibia ( J:211773 )

IMPC - RBRC

Allelic Composition	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺
Genetic Background	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Ucd
Cell Lines	EPD0045_1_A11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1b(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (498 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

endocrine/exocrine glands

small adrenal glands ( J:211773 )

IMPC - TCP

Allelic Composition	Nxn^{tm1b(EUCOMM)Wtsi}/Nxn⁺
Genetic Background	C57BL/6N-Nxn^{tm1b(EUCOMM)Wtsi}/Wtsi
Cell Lines	EPD0045_1_B11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxn^{tm1b(EUCOMM)Wtsi} mutation (2 available); any Nxn mutation (498 available)

Data Sources

IMPC Data for Nxn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

craniofacial

abnormal cranium morphology ( J:211773 )

IMPC - WTSI

abnormal snout morphology ( J:211773 )

IMPC - WTSI

growth/size/body

abnormal snout morphology ( J:211773 )

IMPC - WTSI

skeleton

abnormal cranium morphology ( J:211773 )

IMPC - WTSI

vision/eye

abnormal eyelid morphology ( J:211773 )

IMPC - WTSI

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 01/28/2026 MGI 6.24