All Phenotypes t<+> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

t⁺
wild type
MGI:1857759

Summary

59 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	t^h7m/t⁺	Not Specified	MGI:5465170
ht2	t^h7m2/t⁺	Not Specified	MGI:5465171
ht3	t^low2H/t⁺	Not Specified	MGI:5465167
ht4	t^Tu3/t⁺	Not Specified	MGI:5284994
cx5	T^24H/T⁺ t^h2/t⁺	involves: 101/H * C3H/HeH	MGI:5471531
cx6	T^34H/T⁺ t^w32/t⁺	involves: 101/H * C3H/HeH * STOCK T^34H * TFH	MGI:3719857
cx7	T^30H/T⁺ t⁶/t⁺	involves: 101/H * C3H/HeH * TFH	MGI:3719859
cx8	T^31H/T⁺ t^w32/t⁺	involves: 101/H * C3H/HeH * TFH	MGI:3719842
cx9	T^30H/T⁺ t^w32/t⁺	involves: 101/H * C3H/HeH * TFH	MGI:3719846
cx10	T^33H/T⁺ t^w32/t⁺	involves: 101/H * C3H/HeH * TFH	MGI:3719847
cx11	T^36H/T⁺ t^w32/t⁺	involves: 101/H * C3H/HeH * TFH	MGI:3719852
cx12	T^32H/T⁺ t^h51/t⁺	involves: 101/H * C3H/HeH * TFH	MGI:3719853
cx13	T^32H/T⁺ t^w32/t⁺	involves: 101/H * C3H/HeH * TFH	MGI:3719856
cx14	T^32H/T⁺ t⁶/t⁺	involves: 101/H * C3H/HeH * TFH	MGI:3719860
cx15	T^36H/T⁺ t⁶/t⁺	involves: 101/H * C3H/HeH * TFH	MGI:3719862
cx16	T^22H/T⁺ t^w32/t⁺	involves: 101/H * C3H/HeH * TFH	MGI:3719863
cx17	Nme3^tm1Bgh/Nme3⁺ t^w18/t⁺	involves: 129S1/Sv	MGI:5319399
cx18	Nme3^tm1Bgh/Nme3⁺ t^h49/t⁺	involves: 129S1/Sv	MGI:5319401
cx19	t^w73 +/t⁺ Del(17D17Jcs40-D17Mit198)7Jcs	involves: 129S4/SvJae * C3HeB/FeJ * C57BL/6J	MGI:5428468
cx20	t^w18/t⁺ Tiam2^tm1Bgh/Tiam2^tm1Bgh	involves: 129S/SvEv * 129S1/Sv	MGI:6360722
cx21	t^w18/t⁺ Tiam2^tm1Bgh/Tiam2⁺ Tg(Ace-Tiam2)C11S1Bgh/0	involves: 129S/SvEv * 129S1/Sv	MGI:6360725
cx22	t⁶/Tagap^tm1Bgh	involves: BALB/c * BTBR/TF * FVB/N	MGI:3639742
cx23	T^4J/t⁶	involves: BALB/cBy	MGI:4830251
cx24	T^29H/T⁺ t^w32/t⁺	involves: BALB/c * TFH	MGI:3719854
cx25	T^29H/T⁺ t⁶/t⁺	involves: BALB/c * TFH	MGI:3719858
cx26	Fgd2^tm1Bgh/Fgd2⁺ t^h49/t⁺	involves: BTBR	MGI:3700705
cx27	Itpr3^tf/Itpr3⁺ T/T⁺ t^hr4/t⁺	involves: BTBR	MGI:5465159
cx28	T/T⁺ t^h7m2/t⁺ Itpr3^tf/Itpr3⁺	involves: BTBR	MGI:5465016
cx29	t⁺/t^h20 Itpr3^tf/Itpr3^tf	involves: BTBR	MGI:4868369
cx30	Itpr3^tf/Itpr3⁺ t^h7m2/t⁺	involves: BTBR	MGI:5465015
cx31	T/t^wPas1	involves: BTBR/Nev T * M. m. brevirostris	MGI:4821115
cx32	T^c/t^h51 Tg(T)118.9Bgh/0	involves: C57BL/6 * CBA	MGI:3784944
cx33	t^h49/t⁺ Tg(Ace-Tiam2)C1L2Bgh/0	involves: C57BL/6J	MGI:6360724
cx34	t^h49/t⁺ Tg(Ace-Tiam2)C1L1Bgh/0	involves: C57BL/6J	MGI:6360723
cx35	T^5J/t⁶	involves: C57BL/6J	MGI:4830536
cx36	T/t^btm	involves: C57BL/6 * MOL-NIS	MGI:4457262
cx37	T/t^wPas2	involves: M. m. brevirostris	MGI:4821153
cx38	T/t^wPas3	involves: M. m. domesticus	MGI:4821268
cx39	T/t^w73	involves: M. m. musculus	MGI:5288480
cx40	T/t^btm	MOL-NIS	MGI:4819839
cx41	T/T⁺ t^h7m/t⁺	Not Specified	MGI:5465011
cx42	T t⁺/T⁺ t^Tu3	Not Specified	MGI:5284985
cx43	T t^h20/T⁺ t⁺	Not Specified	MGI:4868366
cx44	T/T⁺ t^h7m2/t⁺	Not Specified	MGI:5465018
cx45	T/T⁺ t^hr1/t⁺	Not Specified	MGI:5465026
cx46	T/T⁺ t^hr15/t⁺	Not Specified	MGI:5465028
cx47	T/T⁺ t^hr4/t⁺	Not Specified	MGI:5465155
cx48	T t⁺/T⁺ t^h45	Not Specified	MGI:4868204
cx49	T/T⁺ t^low2H/t⁺	Not Specified	MGI:5465165
cx50	T t⁺/T⁺ t^h17	Not Specified	MGI:4844309
cx51	T t^s6/T⁺ t⁺	Not Specified	MGI:4839335
cx52	T/t⁶	Not Specified	MGI:3663265
cx53	T/t^w3	Not Specified	MGI:5906043
cx54	T/t^AE5	Not Specified	MGI:4461426
cx55	T/t⁴	Not Specified	MGI:4461305
cx56	T/t^wN27	Not Specified	MGI:4460903
cx57	T/t^ks1	Not Specified	MGI:4458399
cx58	T^h/t¹³	Not Specified	MGI:4360117
cx59	t⁶/t⁺ Tg(Ace-Nme3)H17Bgh/0	Not Specified	MGI:5319402

Allelic Composition	t^h7m/t⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
t^h7m mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

reproductive system phenotype ( J:34190 )

N	• males exhibit normal transmission ratio

Allelic Composition	t^h7m2/t⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
t^h7m2 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:34190 )

• male mice exhibit moderately high transmission of t^h7m2

Allelic Composition	t^low2H/t⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
t^low2H mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:183153 )

• males give low ratio of t^low2H young

Allelic Composition	t^Tu3/t⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
t^Tu3 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

limbs/digits/tail phenotype ( J:6700 )

N	• mice of this genotype have normal tails although combinations of some other t haplotypes and T produce short-tailed mice

Allelic Composition	T^24H/T⁺ t^h2/t⁺
Genetic Background	involves: 101/H * C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^24H mutation (0 available); any T mutation (60 available)
t^h2 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:169366 )

Allelic Composition	T^34H/T⁺ t^w32/t⁺
Genetic Background	involves: 101/H * C3H/HeH * STOCK T^34H * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^34H mutation (0 available); any T mutation (60 available)
t^w32 mutation (1 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:62655 )

• fewer than expected carried the T^34H allele

Allelic Composition	T^30H/T⁺ t⁶/t⁺
Genetic Background	involves: 101/H * C3H/HeH * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^30H mutation (0 available); any T mutation (60 available)
t⁶ mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:62655 )

• the transmission ratio distortion associated with t⁶ is increased

Allelic Composition	T^31H/T⁺ t^w32/t⁺
Genetic Background	involves: 101/H * C3H/HeH * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^31H mutation (0 available); any T mutation (60 available)
t^w32 mutation (1 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

male infertility ( J:62655 )

Allelic Composition	T^30H/T⁺ t^w32/t⁺
Genetic Background	involves: 101/H * C3H/HeH * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^30H mutation (0 available); any T mutation (60 available)
t^w32 mutation (1 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

male infertility ( J:62655 )

Allelic Composition	T^33H/T⁺ t^w32/t⁺
Genetic Background	involves: 101/H * C3H/HeH * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^33H mutation (0 available); any T mutation (60 available)
t^w32 mutation (1 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:62655 )

• fewer than expected carried the T^33H allele

reduced male fertility ( J:62655 )

• male fertility is low

Allelic Composition	T^36H/T⁺ t^w32/t⁺
Genetic Background	involves: 101/H * C3H/HeH * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^36H mutation (0 available); any T mutation (60 available)
t^w32 mutation (1 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:62655 )

• viability is poor and no males survive into adulthood

Allelic Composition	T^32H/T⁺ t^h51/t⁺
Genetic Background	involves: 101/H * C3H/HeH * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^32H mutation (0 available); any T mutation (60 available)
t^h51 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:62655 )

• fewer than expected offsprings carried the t^h51 allele

Allelic Composition	T^32H/T⁺ t^w32/t⁺
Genetic Background	involves: 101/H * C3H/HeH * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^32H mutation (0 available); any T mutation (60 available)
t^w32 mutation (1 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:62655 )

• fewer than expected carried the T^32H allele

Allelic Composition	T^32H/T⁺ t⁶/t⁺
Genetic Background	involves: 101/H * C3H/HeH * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^32H mutation (0 available); any T mutation (60 available)
t⁶ mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:62655 )

• the transmission ratio distortion associated with t⁶ is increased

Allelic Composition	T^36H/T⁺ t⁶/t⁺
Genetic Background	involves: 101/H * C3H/HeH * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^36H mutation (0 available); any T mutation (60 available)
t⁶ mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:62655 )

• the transmission ratio distortion associated with t⁶ is increased

Allelic Composition	T^22H/T⁺ t^w32/t⁺
Genetic Background	involves: 101/H * C3H/HeH * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^22H mutation (0 available); any T mutation (60 available)
t^w32 mutation (1 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

male infertility ( J:62655 )

Allelic Composition	Nme3^tm1Bgh/Nme3⁺ t^w18/t⁺
Genetic Background	involves: 129S1/Sv

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nme3^tm1Bgh mutation (0 available); any Nme3 mutation (10 available)
t^w18 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:183481 )

• mice exhibit increased transmission of the t-haplotype compared with wild-type mice

Allelic Composition	Nme3^tm1Bgh/Nme3⁺ t^h49/t⁺
Genetic Background	involves: 129S1/Sv

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nme3^tm1Bgh mutation (0 available); any Nme3 mutation (10 available)
t^h49 mutation (1 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:183481 )

• mice exhibit increased transmission of the t-haplotype compared with wild-type mice

Allelic Composition	t^w73 +/t⁺ Del(17D17Jcs40-D17Mit198)7Jcs
Genetic Background	involves: 129S4/SvJae * C3HeB/FeJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(17D17Jcs40-D17Mit198)7Jcs mutation (0 available); any Del(17D17Jcs40-D17Mit198)7Jcs mutation (0 available)
t^w73 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

neonatal lethality, complete penetrance ( J:99488 )

• the deletion in this genotype identifies a locus on haplotype t^w73 that causes lethality at birth, t^w73lab

Allelic Composition	t^w18/t⁺ Tiam2^tm1Bgh/Tiam2^tm1Bgh
Genetic Background	involves: 129S/SvEv * 129S1/Sv

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tiam2^tm1Bgh mutation (0 available); any Tiam2 mutation (105 available)
t^w18 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:273736 )

• whether alleles are in cis or trans, mice exhibit reduced transmission of t^w18 compared with wild-type mice

Allelic Composition	t^w18/t⁺ Tiam2^tm1Bgh/Tiam2⁺ Tg(Ace-Tiam2)C11S1Bgh/0
Genetic Background	involves: 129S/SvEv * 129S1/Sv

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Ace-Tiam2)C11S1Bgh mutation (0 available)
Tiam2^tm1Bgh mutation (0 available); any Tiam2 mutation (105 available)
t^w18 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:273736 )

• mice exhibit increased transmission of t^w18 compared with wild-type mice

Allelic Composition	t⁶/Tagap^tm1Bgh
Genetic Background	involves: BALB/c * BTBR/TF * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
t⁶ mutation (0 available); any t mutation (19 available)
Tagap^tm1Bgh mutation (0 available); any Tagap mutation (22 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

abnormal meiosis ( J:100859 )

abnormal male meiosis ( J:100859 )

• reduced transmission found for sperm bearing t⁶

abnormal sperm motility ( J:100859 )

• compromised sperm motility is inferred as overexpression of Tagap1 results in greater than normal t⁶ haplotype transmission

asthenozoospermia ( J:100859 )

cellular

abnormal meiosis ( J:100859 )

abnormal male meiosis ( J:100859 )

• reduced transmission found for sperm bearing t⁶

abnormal sperm motility ( J:100859 )

• compromised sperm motility is inferred as overexpression of Tagap1 results in greater than normal t⁶ haplotype transmission

asthenozoospermia ( J:100859 )

Allelic Composition	T^4J/t⁶
Genetic Background	involves: BALB/cBy

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^4J mutation (1 available); any T mutation (60 available)
t⁶ mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:30778 )

Allelic Composition	T^29H/T⁺ t^w32/t⁺
Genetic Background	involves: BALB/c * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^29H mutation (0 available); any T mutation (60 available)
t^w32 mutation (1 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:62655 )

• no offsprings carried the T^29H allele

Allelic Composition	T^29H/T⁺ t⁶/t⁺
Genetic Background	involves: BALB/c * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^29H mutation (0 available); any T mutation (60 available)
t⁶ mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:62655 )

• the transmission ratio distortion associated with t⁶ is increased

Allelic Composition	Fgd2^tm1Bgh/Fgd2⁺ t^h49/t⁺
Genetic Background	involves: BTBR

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgd2^tm1Bgh mutation (0 available); any Fgd2 mutation (33 available)
t^h49 mutation (1 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:117419 )

• mice transmitted the t^h49 allele to only 35% of their offspring compared to a transmission rate of 47% for mice without the Fgd2 mutant allele

Allelic Composition	Itpr3^tf/Itpr3⁺ T/T⁺ t^hr4/t⁺
Genetic Background	involves: BTBR

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itpr3^tf mutation (20 available); any Itpr3 mutation (174 available)
T mutation (23 available); any T mutation (60 available)
t^hr4 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:169366 )

• high transmission ratio distortion in favour of the t^hr4 haplotype from males

Allelic Composition	T/T⁺ t^h7m2/t⁺ Itpr3^tf/Itpr3⁺
Genetic Background	involves: BTBR

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itpr3^tf mutation (20 available); any Itpr3 mutation (174 available)
T mutation (23 available); any T mutation (60 available)
t^h7m2 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

reproductive system phenotype ( J:34190 )

N	• mice exhibit normal fertility

Allelic Composition	t⁺/t^h20 Itpr3^tf/Itpr3^tf
Genetic Background	involves: BTBR

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itpr3^tf mutation (20 available); any Itpr3 mutation (174 available)
t^h20 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

integument

abnormal hair growth ( J:5889 )

• due to a deletion associated with t^h20, this genotype looks like a mouse homozygous for the recessive mutation tufted

Allelic Composition	Itpr3^tf/Itpr3⁺ t^h7m2/t⁺
Genetic Background	involves: BTBR

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itpr3^tf mutation (20 available); any Itpr3 mutation (174 available)
t^h7m2 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

reproductive system phenotype ( J:34190 )

N	• mice exhibit normal fertility

Allelic Composition	T/t^wPas1
Genetic Background	involves: BTBR/Nev T * M. m. brevirostris

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^wPas1 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:6461 )

• when males of this genotype are mated to wild-type females the t-haplotype appears among teh offspring more frequently than expected

reproductive system

transmission ratio distortion ( J:6461 )

Allelic Composition	T^c/t^h51 Tg(T)118.9Bgh/0
Genetic Background	involves: C57BL/6 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^c mutation (3 available); any T mutation (60 available)
Tg(T)118.9Bgh mutation (0 available)
t^h51 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

abnormal tail morphology ( J:3956 )

• six of seven found to have short tails with the seventh having no tail; this is a partial rescue of the compound heterozygous phenotype in the absence of the transgene wherein sevin out of sevin have a tailless phenotype

Allelic Composition	t^h49/t⁺ Tg(Ace-Tiam2)C1L2Bgh/0
Genetic Background	involves: C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Ace-Tiam2)C1L2Bgh mutation (0 available)
t^h49 mutation (1 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:273736 )

• mice exhibit reduced transmission of t^h49 compared with wild-type mice

Allelic Composition	t^h49/t⁺ Tg(Ace-Tiam2)C1L1Bgh/0
Genetic Background	involves: C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Ace-Tiam2)C1L1Bgh mutation (0 available)
t^h49 mutation (1 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:273736 )

• mice exhibit reduced transmission of t^h49 compared with wild-type mice

Allelic Composition	T^5J/t⁶
Genetic Background	involves: C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^5J mutation (1 available); any T mutation (60 available)
t⁶ mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:78379 )

Allelic Composition	T/t^btm
Genetic Background	involves: C57BL/6 * MOL-NIS

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^btm mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

abnormal rostral-caudal body axis extension ( J:21054 )

• attenuated development of the posterior part of the body

abnormal neural tube morphology ( J:21054 )

• generally distorted, duplicated or fused with the mesenchyme

meningomyelocele ( J:21054 )

• presents as a dorsal blood blister in the lumbosacral region

abnormal notochord morphology ( J:21054 )

• E11-12 embryos show abnormalities in the medio-dorsal area

notochord degeneration ( J:21054 )

• seen in E11-12 embryos

split notochord ( J:21054 )

• seen in E11-12 embryos

abnormal tail bud morphology ( J:21054 )

• at E10 a constriction occurs as the tail develops

nervous system

abnormal neural tube morphology ( J:21054 )

• generally distorted, duplicated or fused with the mesenchyme

meningomyelocele ( J:21054 )

• presents as a dorsal blood blister in the lumbosacral region

abnormal spinal cord morphology ( J:21054 )

• posterior to the lumbosacral level the cord is severely distorted or duplicated and devoid of vertebrae

limbs/digits/tail

absent caudal vertebrae ( J:21054 )

abnormal tail development ( J:21054 )

abnormal tail bud morphology ( J:21054 )

• at E10 a constriction occurs as the tail develops

absent tail ( J:21054 )

• mice with this genotype lack a tail at birth and have blood listers or red scars on the dorsal skin at the middle of the lumbosacral region

skeleton

meningomyelocele ( J:21054 )

• presents as a dorsal blood blister in the lumbosacral region

absent caudal vertebrae ( J:21054 )

abnormal thoracic vertebrae morphology ( J:21054 )

• rib fusions, lack of vertebral bodies and arches

abnormal lumbar vertebrae morphology ( J:21054 )

• rib fusions, lack of vertebral bodies and arches

absent sacral vertebrae ( J:21054 )

absent vertebral arch ( J:21054 )

• an abnormality of thoracic and lumbar vertebrae

absent vertebral body ( J:21054 )

• an abnormality of thoracic and lumbar vertebrae

absent vertebrae ( J:21054 )

Allelic Composition	T/t^wPas2
Genetic Background	involves: M. m. brevirostris

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^wPas2 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:6461 )

reproductive system

transmission ratio distortion ( J:6461 )

• in a test cross with a wild-type female mouse the t-haplotype is seen in offspring less frequently than expected

Allelic Composition	T/t^wPas3
Genetic Background	involves: M. m. domesticus

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^wPas3 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:6461 )

reproductive system

transmission ratio distortion ( J:6461 )

• when males of this genotype are mated to wild-type females the t haplotype occurs among the offspring more frequently than expected

Allelic Composition	T/t^w73
Genetic Background	involves: M. m. musculus

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^w73 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:175677 )

• males of this genotype transmit t^w73 to 88.6 per cent of offspring

limbs/digits/tail

absent tail ( J:175677 )

• all mice of this genotype are tailless

Allelic Composition	T/t^btm
Genetic Background	MOL-NIS

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^btm mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

decreased survivor rate ( J:14919 )

• all mice are dead by 60 days of age; the few longest-lived have hind-limb paralysis

perinatal lethality, incomplete penetrance ( J:14919 )

• most die shortly after birth and have a blood blister in the lumbosacral area and hind-limb paralysis

limbs/digits/tail

absent tail ( J:14919 )

• all mice of this genotype are tailless

reproductive system

reproductive system phenotype ( J:14919 )

N	• mice are fertile and there is no evidence of transmission ratio distortion

Allelic Composition	T/T⁺ t^h7m/t⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^h7m mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:34190 )

Allelic Composition	T t⁺/T⁺ t^Tu3
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^Tu3 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

limbs/digits/tail phenotype ( J:6700 )

N	• the tail length is normal although a mouse inheriting a t haplotype with T is frequently tailless

Allelic Composition	T t^h20/T⁺ t⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^h20 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:5889 )

Allelic Composition	T/T⁺ t^h7m2/t⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^h7m2 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:34190 )

Allelic Composition	T/T⁺ t^hr1/t⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^hr1 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:183153 )

Allelic Composition	T/T⁺ t^hr15/t⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^hr15 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:192386 )

Allelic Composition	T/T⁺ t^hr4/t⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^hr4 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:169366 )

Allelic Composition	T t⁺/T⁺ t^h45
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^h45 mutation (1 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:7443 )

Allelic Composition	T/T⁺ t^low2H/t⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^low2H mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

limbs/digits/tail phenotype ( J:183153 )

N	• no effect on tail length

Allelic Composition	T t⁺/T⁺ t^h17
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^h17 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:5889 )

• mice with this genotype have short tails; they are not tailless as are mice heterozygous for brachyury and carrying any of the majority of other t haplotypes

• there is no transmission ratio distortion as might be expected from males of this genotype

Allelic Composition	T t^s6/T⁺ t⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^s6 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:6478 )

• 85% of offspring produced from 3 matings of Tt^s6 males to wild-type females are short-tailed; 15% are normal-tailed

Allelic Composition	T/t⁶
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t⁶ mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

decreased ventral ectodermal ridge size ( J:15081 )

• the size of the ventral ectodermal ridge of the tail (VER) is reduced to 69% of the normal size

embryo

abnormal notochord morphology ( J:15081 )

• the notochord is increased in bulk not only in the distal growth zone (as in T heterozygotes) but in the whole tail, in the cloacal region and even more anteriorly in the lumbar region and has large lumina

• the notochord is present throughout the length of the tail, however it becomes incorporated into the neural tube throughout the tail and often the cloacal region

decreased ventral ectodermal ridge size ( J:15081 )

• the size of the ventral ectodermal ridge of the tail (VER) is reduced to 69% of the normal size

Allelic Composition	T/t^w3
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^w3 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:23652 )

Allelic Composition	T/t^AE5
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^AE5 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

abnormal tail morphology ( J:83862 )

absent tail ( J:83862 )

Allelic Composition	T/t⁴
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t⁴ mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

abnormal tail morphology ( J:36683 )

absent tail ( J:36683 )

reproductive system

transmission ratio distortion ( J:36683 )

• T-bearing gametes are in excess although not uniformly the case from male to male

Allelic Composition	T/t^wN27
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^wN27 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:32745 )

• indicative of the presence of a t haplotype

Allelic Composition	T/t^ks1
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^ks1 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:8922 )

reproductive system

transmission ratio distortion ( J:8922 )

• only 37% of sperm from males of this genotype carry the t^ks1 haplotype

Allelic Composition	T^h/t¹³
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
t¹³ mutation (0 available); any t mutation (19 available)
T^h mutation (0 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:13072 )

Allelic Composition	t⁶/t⁺ Tg(Ace-Nme3)H17Bgh/0
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
t⁶ mutation (0 available); any t mutation (19 available)
Tg(Ace-Nme3)H17Bgh mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:183481 )

• the transmission ratio distortion associated with t⁶ is decreased

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