Tg(Ace-Tiam2)C1L2Bgh
Transgene Detail

Summary

• Symbol: Tg(Ace-Tiam2)C1L2Bgh
• Name: transgene insertion C1L2, Bernhard G Herrmann
• MGI ID: MGI:6360715
• Synonyms: Tg2L
• Transgene: Tg(Ace-Tiam2)C1L2Bgh Location: unknown
• Alliance: Tg(Ace-Tiam2)C1L2Bgh page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The promoter including the transcriptional start site drives expression of the long transcript (with the rabbit beta-globin polyadenylation signal including an intron and the SV40 polyadenylation signal) during spermiogenesis. The expression cassette is flanked by two copies of the chicken beta-globin insulator. Line C1L2 was generated. (J:273736)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:273736 Charron Y, et al., Two isoforms of the RAC-specific guanine nucleotide exchange factor TIAM2 act oppositely on transmission ratio distortion by the mouse t-haplotype. PLoS Genet. 2019 Feb;15(2):e1007964
• All: 1 reference(s)