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Gene Expression Data
Assay Details
Assay
Reference: J:312380 Sun-Wada GH, et al., Vacuolar-type proton ATPase is required for maintenance of apicobasal polarity of embryonic visceral endoderm. Sci Rep. 2021 Sep 29;11(1):19355
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7541123
Gene symbol: Atp6v0c
Gene name: ATPase, H+ transporting, lysosomal V0 subunit C
Antibody: anti-V-ATPase c-subunit
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 3a/b: embryonic day 5.5 (more )
Note: Triple labeled: red - Atp6v0c; blue - Gata6 (assay MGI:7541116); green - Lamp2 (assay MGI:7541124).
Structure Level Pattern Image Note
TS7: embryonic visceral endoderm Strong 3a , 3b1 Highly expressed in the subapical region.
TS7: parietal endoderm Present 3a , 3b2
Specimen 3c/d: embryonic day 5.5; Atp6v0ctm1.1Ywd/Atp6v0ctm1.1Ywd (more )
Note: Triple labeled: red - Atp6v0c; blue - Gata6 (assay MGI:7541116); green - Lamp2 (assay MGI:7541124).
Structure Level Pattern Image Note
TS7: embryonic visceral endoderm Absent 3c , 3d1 Showed only background staining.
TS7: parietal endoderm Absent 3d2 , 3c Showed only background staining.
Specimen 3e/f: embryonic day 5.5 (more )
Note: Triple labeled: red - Atp6v0c; green - Lamp2 (assay MGI:7541124); blue - Snx1 (assay MGI:7541125).
Structure Level Pattern Image Note
TS7: embryonic visceral endoderm Present 3e , 3f Coexpressed with Snx1 in the early endocytic compartments in the subapical cytoplasm. Less expression in the apical vacuoles (Lamp2+).
Specimen 3h/i: embryonic day 5.5; Atp6v0ctm1.1Ywd/Atp6v0ctm1.1Ywd (more )
Note: Triple labeled: red - Atp6v0c; green - Lamp2 (assay MGI:7541124); blue - Snx1 (assay MGI:7541125).
Structure Level Pattern Image Note
TS7: embryonic visceral endoderm Absent 3i , 3h
Specimen S6a/b/c: embryonic day 4.5 (more )
Note: Triple labeled: red - Atp6v0c; green - Gata6 (assay MGI:7541099); blue - Pou5f1 (assay MGI:7541102).
Structure Level Pattern Image Note
TS6: mural trophectoderm Present S6a , S6b , S6c
TS6: polar trophectoderm Present S6a , S6b , S6c
TS6: primitive endoderm Present S6a , S6b , S6c
TS6: epiblast Present S6b , S6c , S6a Weaker expression compared with that of primitive endoderm.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory