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Gene Expression Data
Assay Details
Assay
Reference: J:175544 Dupuis LE, et al., Altered versican cleavage in ADAMTS5 deficient mice; A novel etiology of myxomatous valve disease. Dev Biol. 2011 Sep 1;357(1):152-64
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6279798
Gene symbol: Acta2
Gene name: actin alpha 2, smooth muscle, aorta
Results
Specimen 1J: embryonic day 15.5 (more )
Note: Triple labeled: red - Acta2 (smooth muscle actin); blue - Acta1 (assay MGI:6279797); green - Vcan (cleaved Vcan; assay MGI:6279800).
Structure Level Pattern Image Note
TS23: heart Present 1J
Specimen 6I: embryonic day 17.5 (more )
Note: Double labeled: red - Acta2 (smooth muscle actin); green - Vcan (cleaved Vcan; assay MGI:6279800).
Structure Level Pattern Image Note
TS25: outflow tract cardiac muscle Present 6I
Specimen 6J: embryonic day 17.5; Adamts5tm1Dgen/Adamts5tm1Dgen (more )
Note: Double labeled: red - Acta2 (smooth muscle actin); green - Vcan (cleaved Vcan; assay MGI:6279800).
Structure Level Pattern Image Note
TS25: outflow tract cardiac muscle Present 6J
Specimen 6K: embryonic day 17.5 (more )
Note: Double labeled: red - Acta2 (smooth muscle actin); green - Vcan (cleaved Vcan; assay MGI:6279800).
Structure Level Pattern Image Note
TS25: outflow tract cardiac muscle Present 6K
Specimen 6L: embryonic day 17.5; Adamts5tm1Dgen/Adamts5tm1Dgen (more )
Note: Double labeled: red - Acta2 (smooth muscle actin); green - Vcan (cleaved Vcan; assay MGI:6279800).
Structure Level Pattern Image Note
TS25: outflow tract cardiac muscle Present 6L
Specimen 8A: embryonic day 12.5 (more )
Note: Triple labeled: blue - Acta2 (smooth muscle actin); green - Sox9 (assay MGI:6279802); red - propidium iodide.
Structure Level Pattern Image Note
TS20: outflow tract endocardial cushion Present 8A
Specimen 8B: embryonic day 12.5; Adamts5tm1Dgen/Adamts5tm1Dgen (more )
Note: Triple labeled: blue - Acta2 (smooth muscle actin); green - Sox9 (assay MGI:6279802); red - propidium iodide.
Structure Level Pattern Image Note
TS20: outflow tract endocardial cushion Present 8B
Specimen S1A: embryonic day 17.5 (more )
Note: Triple labeled: blue - Acta2; green - Bgn (assay MGI:6279803); red - propidium iodide.
Structure Level Pattern Image Note
TS25: pulmonary valve Absent S1A
Specimen S1B: embryonic day 17.5; Adamts5tm1Dgen/Adamts5tm1Dgen (more )
Note: Triple labeled: blue - Acta2; green - Bgn (assay MGI:6279803); red - propidium iodide.
Structure Level Pattern Image Note
TS25: pulmonary valve Absent S1B
Specimen S1C: embryonic day 17.5 (more )
Note: Triple labeled: blue - Acta2; green - Bgn (assay MGI:6279803); red - propidium iodide.
Structure Level Pattern Image Note
TS25: pulmonary valve Absent S1C
Specimen S1D: embryonic day 17.5; Adamts5tm1Dgen/Adamts5tm1Dgen (more )
Note: Triple labeled: blue - Acta2; green - Bgn (assay MGI:6279803); red - propidium iodide.
Structure Level Pattern Image Note
TS25: pulmonary valve Absent S1D
Specimen S2A: embryonic day 17.5 (more )
Note: Triple labeled: red - Acta2 (smooth muscle actin); blue - Acta1 (sarcomeric actin; assay MGI:6279797); green - Vcan (intact Vcan; assay MGI:6279799).
Structure Level Pattern Image Note
TS25: heart Present S2A
Specimen S2B: embryonic day 17.5; Adamts5tm1Dgen/Adamts5tm1Dgen (more )
Note: Triple labeled: red - Acta2 (smooth muscle actin); blue - Acta1 (sarcomeric actin; assay MGI:6279797); green - Vcan (intact Vcan; assay MGI:6279799).
Structure Level Pattern Image Note
TS25: heart Present S2B
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory