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Gene Expression Data
Assay Details
Assay
Reference: J:175544 Dupuis LE, et al., Altered versican cleavage in ADAMTS5 deficient mice; A novel etiology of myxomatous valve disease. Dev Biol. 2011 Sep 1;357(1):152-64
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6279803
Gene symbol: Bgn
Gene name: biglycan
Results
Specimen S1A: embryonic day 17.5 (more )
Note: Triple labeled: green - Bgn; blue - Acta1 (sarcomeric actin; assay MGI:6279797); red - propidium iodide.
Structure Level Pattern Image Note
TS25: pulmonary valve Trace Regionally restricted S1A Authors report very little expression at E17.5 in both wild type and mutant pulmonary valves, notably at the attachment point of pulmonary valve cusps.
Specimen S1B: embryonic day 17.5; Adamts5tm1Dgen/Adamts5tm1Dgen (more )
Note: Triple labeled: green - Bgn; blue - Acta1 (sarcomeric actin; assay MGI:6279797); red - propidium iodide.
Structure Level Pattern Image Note
TS25: pulmonary valve Trace Regionally restricted S1B Authors report very little expression at E17.5 in both wild type and mutant pulmonary valves, notably at the attachment point of pulmonary valve cusps.
Specimen S1C: embryonic day 17.5 (more )
Note: Triple labeled: green - Bgn; blue - Acta1 (sarcomeric actin; assay MGI:6279797); red - propidium iodide.
Structure Level Pattern Image Note
TS25: pulmonary valve Trace S1C Authors report very little expression at E17.5 in pulmonary valves.
Specimen S1D: embryonic day 17.5; Adamts5tm1Dgen/Adamts5tm1Dgen (more )
Note: Triple labeled: green - Bgn; blue - Acta1 (sarcomeric actin; assay MGI:6279797); red - propidium iodide.
Structure Level Pattern Image Note
TS25: pulmonary valve Trace S1D Authors report very little expression at E17.5 in pulmonary valves.
Specimen S1G: postnatal adult (more )
Note: Triple labeled: green - Bgn; blue - Acta1 (sarcomeric actin; assay MGI:6279797); red - propidium iodide.
Structure Level Pattern Image Note
TS28: pulmonary valve Present S1G Expression readily detected in pulmonary valves from both wild type and mutant adult mice.
Specimen S1H: postnatal adult; Adamts5tm1Dgen/Adamts5tm1Dgen (more )
Note: Triple labeled: green - Bgn; blue - Acta1 (sarcomeric actin; assay MGI:6279797); red - propidium iodide.
Structure Level Pattern Image Note
TS28: pulmonary valve Present Regionally restricted S1H Authors report misexpression in the pulmonary valves, but extent of expression was not increased compared to wild type littermates.
Specimen S1I: postnatal adult (more )
Note: Double labeled: green - Bgn; red - propidium iodide.
Structure Level Pattern Image Note
TS28: pulmonary valve Present S1I Expression readily detected in pulmonary valves from both wild type and mutant adult mice.
Specimen S1J: postnatal adult; Adamts5tm1Dgen/Adamts5tm1Dgen (more )
Note: Double labeled: green - Bgn; red - propidium iodide.
Structure Level Pattern Image Note
TS28: pulmonary valve Present Regionally restricted S1J Authors report misexpression in the pulmonary valves, but extent of expression was not increased compared to wild type littermates.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
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