About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:175544 Dupuis LE, et al., Altered versican cleavage in ADAMTS5 deficient mice; A novel etiology of myxomatous valve disease. Dev Biol. 2011 Sep 1;357(1):152-64
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6279797
Gene symbol: Acta1
Gene name: actin alpha 1, skeletal muscle
Results
Specimen 1C: embryonic day 12.5 (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Adamts5 (assay MGI:6279796); red - propidium iodide.
Structure Level Pattern Image Note
TS20: heart Present 1C
Specimen 1D: embryonic day 12.5 (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Adamts5 (assay MGI:6279796); red - propidium iodide.
Structure Level Pattern Image Note
TS20: heart Present 1D
Specimen 1J: embryonic day 15.5 (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Adamts5 (assay MGI:6279796); red - Acta2 (smooth muscle actin; assay MGI:6279798).
Structure Level Pattern Image Note
TS23: heart Present 1J
Specimen 6A: embryonic day 12.5 (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Vcan (intact Vcan; assay MGI:6279799); red - propidium iodide.
Structure Level Pattern Image Note
TS20: heart Present 6A
Specimen 6B: embryonic day 12.5; Adamts5tm1Dgen/Adamts5tm1Dgen (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Vcan (intact Vcan; assay MGI:6279799); red - propidium iodide.
Structure Level Pattern Image Note
TS20: heart Present 6B
Specimen 6G: embryonic day 14.5 (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Vcan (cleaved Vcan; assay MGI:6279800); red - propidium iodide.
Structure Level Pattern Image Note
TS22: heart ventricle Present 6G
Specimen 6H: embryonic day 14.5; Adamts5tm1Dgen/Adamts5tm1Dgen (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Vcan (cleaved Vcan; assay MGI:6279800); red - propidium iodide.
Structure Level Pattern Image Note
TS22: heart ventricle Present 6H
Specimen 7A: embryonic day 15.5 (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Bmp2 (assay MGI:6279801); red - propidium iodide.
Structure Level Pattern Image Note
TS23: heart ventricle Present 7A
Specimen 7B: embryonic day 15.5; Adamts5tm1Dgen/Adamts5tm1Dgen (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Bmp2 (assay MGI:6279801); red - propidium iodide.
Structure Level Pattern Image Note
TS23: heart ventricle Present 7B
Specimen 9A: embryonic day 17.5 (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Vcan (intact Vcan; assay MGI:6279799); red - propidium iodide.
Structure Level Pattern Image Note
TS25: heart right ventricle Present 9A
Specimen 9B: embryonic day 17.5; Adamts5tm1Dgen/Adamts5tm1Dgen (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Vcan (intact Vcan; assay MGI:6279799); red - propidium iodide.
Structure Level Pattern Image Note
TS25: heart right ventricle Present 9B
Specimen 9P: embryonic day 17.5 (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Bmp2 (assay MGI:6279801); red - propidium iodide.
Structure Level Pattern Image Note
TS25: heart right ventricle Present 9P
Specimen 9Q: embryonic day 17.5; Adamts5tm1Dgen/Adamts5tm1Dgen (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Bmp2 (assay MGI:6279801); red - propidium iodide.
Structure Level Pattern Image Note
TS25: heart right ventricle Present 9Q
Specimen S1G: postnatal adult (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Bgn (assay MGI:6279803); red - propidium iodide.
Structure Level Pattern Image Note
TS28: heart right ventricle Present S1G
Specimen S1H: postnatal adult; Adamts5tm1Dgen/Adamts5tm1Dgen (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Bgn (assay MGI:6279803); red - propidium iodide.
Structure Level Pattern Image Note
TS28: heart right ventricle Present S1H
Specimen S2A: embryonic day 17.5 (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Vcan (intact Vcan; assay MGI:6279799); red - propidium iodide.
Structure Level Pattern Image Note
TS25: heart ventricle Present S2A
Specimen S2B: embryonic day 17.5; Adamts5tm1Dgen/Adamts5tm1Dgen (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Vcan (intact Vcan; assay MGI:6279799); red - propidium iodide.
Structure Level Pattern Image Note
TS25: heart ventricle Present S2B
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory