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Gene Expression Data
Assay Details
Assay
Reference: J:175544 Dupuis LE, et al., Altered versican cleavage in ADAMTS5 deficient mice; A novel etiology of myxomatous valve disease. Dev Biol. 2011 Sep 1;357(1):152-64
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6279797
Gene symbol: Acta1
Gene name: actin alpha 1, skeletal muscle
Results
Specimen 1C: embryonic day 12.5 (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Adamts5 (assay MGI:6279796); red - propidium iodide.
Structure Level Pattern Image Note
TS20: heart Present 1C

Specimen 1D: embryonic day 12.5 (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Adamts5 (assay MGI:6279796); red - propidium iodide.
Structure Level Pattern Image Note
TS20: heart Present 1D

Specimen 1J: embryonic day 15.5 (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Adamts5 (assay MGI:6279796); red - Acta2 (smooth muscle actin; assay MGI:6279798).
Structure Level Pattern Image Note
TS23: heart Present 1J

Specimen 6A: embryonic day 12.5 (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Vcan (intact Vcan; assay MGI:6279799); red - propidium iodide.
Structure Level Pattern Image Note
TS20: heart Present 6A

Specimen 6B: embryonic day 12.5; Adamts5tm1Dgen/Adamts5tm1Dgen (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Vcan (intact Vcan; assay MGI:6279799); red - propidium iodide.
Structure Level Pattern Image Note
TS20: heart Present 6B

Specimen 6G: embryonic day 14.5 (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Vcan (cleaved Vcan; assay MGI:6279800); red - propidium iodide.
Structure Level Pattern Image Note
TS22: heart ventricle Present 6G

Specimen 6H: embryonic day 14.5; Adamts5tm1Dgen/Adamts5tm1Dgen (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Vcan (cleaved Vcan; assay MGI:6279800); red - propidium iodide.
Structure Level Pattern Image Note
TS22: heart ventricle Present 6H

Specimen 7A: embryonic day 15.5 (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Bmp2 (assay MGI:6279801); red - propidium iodide.
Structure Level Pattern Image Note
TS23: heart ventricle Present 7A

Specimen 7B: embryonic day 15.5; Adamts5tm1Dgen/Adamts5tm1Dgen (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Bmp2 (assay MGI:6279801); red - propidium iodide.
Structure Level Pattern Image Note
TS23: heart ventricle Present 7B

Specimen 9A: embryonic day 17.5 (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Vcan (intact Vcan; assay MGI:6279799); red - propidium iodide.
Structure Level Pattern Image Note
TS25: heart right ventricle Present 9A

Specimen 9B: embryonic day 17.5; Adamts5tm1Dgen/Adamts5tm1Dgen (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Vcan (intact Vcan; assay MGI:6279799); red - propidium iodide.
Structure Level Pattern Image Note
TS25: heart right ventricle Present 9B

Specimen 9P: embryonic day 17.5 (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Bmp2 (assay MGI:6279801); red - propidium iodide.
Structure Level Pattern Image Note
TS25: heart right ventricle Present 9P

Specimen 9Q: embryonic day 17.5; Adamts5tm1Dgen/Adamts5tm1Dgen (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Bmp2 (assay MGI:6279801); red - propidium iodide.
Structure Level Pattern Image Note
TS25: heart right ventricle Present 9Q

Specimen S1G: postnatal adult (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Bgn (assay MGI:6279803); red - propidium iodide.
Structure Level Pattern Image Note
TS28: heart right ventricle Present S1G

Specimen S1H: postnatal adult; Adamts5tm1Dgen/Adamts5tm1Dgen (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Bgn (assay MGI:6279803); red - propidium iodide.
Structure Level Pattern Image Note
TS28: heart right ventricle Present S1H

Specimen S2A: embryonic day 17.5 (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Vcan (intact Vcan; assay MGI:6279799); red - propidium iodide.
Structure Level Pattern Image Note
TS25: heart ventricle Present S2A

Specimen S2B: embryonic day 17.5; Adamts5tm1Dgen/Adamts5tm1Dgen (more )
Note: Triple labeled: blue - Acta1 (sarcomeric actin); green - Vcan (intact Vcan; assay MGI:6279799); red - propidium iodide.
Structure Level Pattern Image Note
TS25: heart ventricle Present S2B


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory