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Gene Expression Data
Assay Details
Assay
Reference: J:202451 Del Rio T, et al., In vivo analysis of lrig genes reveals redundant and independent functions in the inner ear. PLoS Genet. 2013 Sep;9(9):e1003824
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5790364
Gene symbol: Nefh
Gene name: neurofilament, heavy polypeptide
Antibody: anti-Neurofilament H (AB5539)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 3I: postnatal day 15; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: blue - Nefh; red - Lrig2 (assay MGI:5790348).
Structure Level Pattern Image Note
TS28: utricle Present 3I' Expression is in innervating fibers.
Specimen 3J: postnatal day 15; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: blue - Nefh; red - Lrig2 (assay MGI:5790348).
Structure Level Pattern Image Note
TS28: saccule Present Regionally restricted 3J' Expression is in innervating fibers.
Specimen 3K: postnatal day 15; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: blue - Nefh; red - Lrig2 (assay MGI:5790348).
Structure Level Pattern Image Note
TS28: inner ear vestibular component Present Regionally restricted 3K Expression is in innervating fibers.
Specimen 4A: embryonic day 12.5; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Triple labeled: blue - Nefh; red - Lrig2 (assay MGI:5790348); green - Lrig1 (assay. MGI:5790359).
Structure Level Pattern Image Note
TS20: cochlea Present Regionally restricted 4A'' Expression is in innervating fibers.
Specimen 4B: embryonic day 16.5; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Triple labeled: blue - Nefh; red - Lrig2 (assay MGI:5790348); green - Lrig1 (assay. MGI:5790359).
Structure Level Pattern Image Note
TS24: cochlea Present Regionally restricted 4B'' Expression is in innervating fibers.
Specimen 4C: postnatal day 15; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Triple labeled: blue - Nefh; red - Lrig2 (assay MGI:5790348); green - Lrig1 (assay. MGI:5790359).
Structure Level Pattern Image Note
TS28: cochlea Present Regionally restricted 4C'' Expression is in innervating fibers.
Specimen 7A: postnatal week 6; Lrig1Gt(GST4169C6)Lex/Lrig1+, Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Flat mount confocal image.
Structure Level Pattern Image Note
TS28: cochlea Present Regionally restricted 7A Expression is in innervating fibers.
Specimen 7B: postnatal week 6; Lrig1Gt(GST4169C6)Lex/Lrig1Gt(GST4169C6)Lex, Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Flat mount confocal image.
Structure Level Pattern Image Note
TS28: cochlea Present Regionally restricted 7B Expression is in innervating fibers.
Specimen 7C: postnatal week 6; Lrig1Gt(GST4169C6)Lex/Lrig1Gt(GST4169C6)Lex, Lrig2Gt(RST656)Byg/Lrig2Gt(RST656)Byg (more )
Note: Flat mount confocal image
Structure Level Pattern Image Note
TS28: cochlea Present Regionally restricted 7C Expression is in innervating fibers.
Specimen S4C: embryonic day 19.0; Lrig1Gt(GST4169C6)Lex/Lrig1+, Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: green - Nefh; red - Myo7a (assay MGI:5790793).
Structure Level Pattern Image Note
TS26: cochlear ganglion Present S4C
Specimen S4D: embryonic day 19.0; Lrig1Gt(GST4169C6)Lex/Lrig1Gt(GST4169C6)Lex, Lrig2Gt(RST656)Byg/Lrig2Gt(RST656)Byg (more )
Note: Double labeled: green - Nefh; red - Myo7a (assay MGI:5790793).
Structure Level Pattern Image Note
TS26: cochlear ganglion Present S4D Expression in this mutant is the same as in wild-type.
Specimen S4E: postnatal adult; Lrig1Gt(GST4169C6)Lex/Lrig1+, Lrig2Gt(RST656)Byg/Lrig2+ (more )
Structure Level Pattern Image Note
TS28: cochlea Present S4E Expression in this mutant is the same as in wild-type.
Specimen S4F: postnatal adult; Lrig1Gt(GST4169C6)Lex/Lrig1Gt(GST4169C6)Lex (more )
Structure Level Pattern Image Note
TS28: cochlea Present S4F Expression in this mutant is the same as in wild-type.
Specimen S4G: postnatal adult; Lrig2Gt(RST656)Byg/Lrig2Gt(RST656)Byg (more )
Structure Level Pattern Image Note
TS28: cochlea Present S4G Expression in this mutant is the same as in wild-type.
Specimen S4H: postnatal adult; Lrig1Gt(GST4169C6)Lex/Lrig1+, Lrig2Gt(RST656)Byg/Lrig2Gt(RST656)Byg (more )
Structure Level Pattern Image Note
TS28: cochlea Present S4H Expression in this mutant is the same as in wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory