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Gene Expression Data
Assay Details
Assay
Reference: J:202451 Del Rio T, et al., In vivo analysis of lrig genes reveals redundant and independent functions in the inner ear. PLoS Genet. 2013 Sep;9(9):e1003824
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5790348
Gene symbol: Lrig2
Gene name: leucine-rich repeats and immunoglobulin-like domains 2
Reporter: Beta-geo
Antibody: anti-B-galactosidase (0855976)
Detection system: Alexa Fluor
Results
Specimen 3A: embryonic day 12.5; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: red - Lrig2; green - Lrig1 (assay MGI:5790359).
Structure Level Pattern Image Note
TS20: inner ear epithelium Present Regionally restricted 3A'' , 3A Expression is in the otic epithelium.
TS20: inner ear mesenchyme Present 3A'' , 3A
TS20: inner ear vestibular component Present Regionally restricted 3A , 3A'' Expression is in the atrium.
Specimen 3B: embryonic day 12.5; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: red - Lrig2; green - Lrig1 (assay MGI:5790359).
Structure Level Pattern Image Note
TS20: inner ear epithelium Present Regionally restricted 3B Expression is in the otic epithelium.
TS20: inner ear mesenchyme Present 3B
TS20: inner ear vestibular component Present Regionally restricted 3B Expression is in the atrium.
Specimen 3E: embryonic day 16.5; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: red - Lrig2; green - Lrig1 (assay MGI:5790359).
Structure Level Pattern Image Note
TS24: inner ear vestibular component Present 3E' , 3E
Specimen 3G: embryonic day 16.5; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: red - Lrig2; green - Lrig1 (assay MGI:5790359).
Structure Level Pattern Image Note
TS24: inner ear vestibular component Present 3G , 3G'
Specimen 3H: postnatal day 15; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: red - Lrig2; green - Lrig1 (assay MGI:5790359).
Structure Level Pattern Image Note
TS28: macula of saccule Present 3H
TS28: macula of utricle Present 3H
TS28: saccule epithelium Present 3H
TS28: utricle epithelium Present 3H
TS28: vestibular ganglion Present 3H
Specimen 3I': postnatal day 15; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: red - Lrig2; blue - Nefh (assay MGI:5790364).
Structure Level Pattern Image Note
TS28: utricle epithelium Present 3I'
Specimen 3J: postnatal day 15; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: red - Lrig2; blue - Nefh (assay MGI:5790364).
Structure Level Pattern Image Note
TS28: saccule epithelium Present 3J'
Specimen 3K: postnatal day 15; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: red - Lrig2; blue - Nefh (assay MGI:5790364).
Structure Level Pattern Image Note
TS28: vestibular epithelium Present Regionally restricted 3K' , 3K Expression is in the sensory epithelium.
Specimen 4A'/A'': embryonic day 12.5; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Triple labeled: red - Lrig2; blue - Nefh (assay MGI:5790364); green - Lrig1 (assay. MGI:5790359).
Structure Level Pattern Image Note
TS20: cochlea epithelium Present Regionally restricted 4A' , 4A''
TS20: inner ear mesenchyme Present Regionally restricted 4A' , 4A''
Specimen 4B'/B'': embryonic day 16.5; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Triple labeled: red - Lrig2; blue - Nefh (assay MGI:5790364); green - Lrig1 (assay. MGI:5790359).
Structure Level Pattern Image Note
TS24: cochlea epithelium Present Regionally restricted 4B' , 4B''
TS24: inner ear mesenchyme Present Regionally restricted 4B' , 4B''
Specimen 4C'/C'': postnatal day 15; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Triple labeled: red - Lrig2; blue - Nefh (assay MGI:5790364); green - Lrig1 (assay. MGI:5790359).
Structure Level Pattern Image Note
TS28: cochlear ganglion Present 4C' , 4C''
TS28: organ of Corti Present 4C' , 4C''
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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