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Gene Expression Data
Assay Details
Assay
Reference: J:202451 Del Rio T, et al., In vivo analysis of lrig genes reveals redundant and independent functions in the inner ear. PLoS Genet. 2013 Sep;9(9):e1003824
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5790359
Gene symbol: Lrig1
Gene name: leucine-rich repeats and immunoglobulin-like domains 1
Antibody: Lrig1 antibody
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 3A: embryonic day 12.5; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: green - Lrig1; red - Lrig2 reporter (assay MGI:5790348).
Structure Level Pattern Image Note
TS20: inner ear vestibular component Present Regionally restricted 3A , 3A' Expression is in the atrium.
TS20: cochlea Present 3A , 3A'
Specimen 3B: embryonic day 12.5; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: green - Lrig1; red - Lrig2 reporter (assay MGI:5790348).
Structure Level Pattern Image Note
TS20: inner ear vestibular component Present Regionally restricted 3B Expression is in the atrium.
Specimen 3C: embryonic day 12.5; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: green - Lrig1; red - Sox2 (assay MGI:5790361).
Structure Level Pattern Image Note
TS20: inner ear vestibular component Present Regionally restricted 3C' , 3C Expression is in the non-sensory areas of the atrium.
Specimen 3D: embryonic day 16.5; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: green - Lrig1; red - Sox2 (assay MGI:5790361).
Structure Level Pattern Image Note
TS24: utricle epithelium Present Regionally restricted 3D' , 3D Expression is in the transitional epithelium.
Specimen 3E: embryonic day 16.5; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: green - Lrig1; red - Lrig2 reporter (assay MGI:5790348).
Structure Level Pattern Image Note
TS24: inner ear vestibular component Present 3E
Specimen 3F: embryonic day 16.5; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: green - Lrig1; red - Sox2 (assay MGI:5790361).
Structure Level Pattern Image Note
TS24: macula of saccule Present Regionally restricted 3F' , 3F Expression is in the extramacular epithelium.
Specimen 3G: embryonic day 16.5; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: green - Lrig1; red - Lrig2 reporter (assay MGI:5790348).
Structure Level Pattern Image Note
TS24: inner ear vestibular component Present 3G
Specimen 3H: postnatal day 15; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: green - Lrig1; red - Lrig2 reporter (assay MGI:5790348).
Structure Level Pattern Image Note
TS28: cochlear ganglion Present 3H
TS28: inner ear vestibular component Present 3H
TS28: macula of saccule Present 3H
TS28: macula of utricle Present 3H
TS28: vestibular ganglion Present 3H
Specimen 3I: postnatal day 15; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Structure Level Pattern Image Note
TS28: utricle Present 3I
Specimen 3J: postnatal day 15; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Structure Level Pattern Image Note
TS28: saccule Present 3J
Specimen 3K'': postnatal day 15; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Structure Level Pattern Image Note
TS28: inner ear vestibular component Present 3K''
Specimen 4A: embryonic day 12.5; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Triple labeled: green - Lrig1; red - Lrig2 (assay MGI:5790348); blue - Nefh (assay. MGI:5790364).
Structure Level Pattern Image Note
TS20: cochlea epithelium Present Regionally restricted 4A'' , 4A Expression is in the non-sensory region.
TS20: inner ear mesenchyme Present Regionally restricted 4A , 4A'' Expression is in the mesenchyme surrounding the spiral ganglion.
Specimen 4B: embryonic day 16.5; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Triple labeled: green - Lrig1; red - Lrig2 (assay MGI:5790348); blue - Nefh (assay. MGI:5790364).
Structure Level Pattern Image Note
TS24: cochlea Present Regionally restricted 4B , 4B'' Expression is in the medial wall.
Specimen 4C: postnatal day 15; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Triple labeled: green - Lrig1; red - Lrig2 (assay MGI:5790348); blue - Nefh (assay. MGI:5790364).
Structure Level Pattern Image Note
TS28: vestibular membrane Present Regionally restricted 4C'' , 4C Expression is at the base of Reissner's membrane at the cell surface.
TS28: cochlear ganglion Present 4C , 4C''
TS28: organ of Corti Present 4C , 4C''
Specimen S3A: embryonic day 18.5 (more )
Note: Double labeled: green - Lrig1; red - Myo7a (assay MGI:5790793).
Structure Level Pattern Image Note
TS26: saccule epithelium Present Regionally restricted S3A , S3A' Expression is in the non-sensory epithelium.
TS26: utricle epithelium Present Regionally restricted S3A , S3A' Expression is in the non-sensory epithelium.
Specimen S3B: embryonic day 18.5; Lrig1Gt(GST4169C6)Lex/Lrig1Gt(GST4169C6)Lex, Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: green - Lrig1; red - Myo7a (assay MGI:5790793).
Structure Level Pattern Image Note
TS26: saccule epithelium Absent S3B' , S3B
TS26: utricle epithelium Absent S3B' , S3B
Specimen S3C: embryonic day 18.5 (more )
Note: Double labeled: green - Lrig1; red - Myo7a (assay MGI:5790793).
Structure Level Pattern Image Note
TS26: inner ear Present Regionally restricted S3C , S3C' Expression is in projections to the utricle and lateral crista.
Specimen S3D: embryonic day 18.5; Lrig1Gt(GST4169C6)Lex/Lrig1Gt(GST4169C6)Lex, Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: green - Lrig1; red - Myo7a (assay MGI:5790793).
Structure Level Pattern Image Note
TS26: inner ear Absent S3D , S3D'
Specimen S3E: embryonic day 18.5 (more )
Note: Double labeled: green - Lrig1; red - Myo7a (assay MGI:5790793).
Structure Level Pattern Image Note
TS26: cochlea Present Regionally restricted S3E , S3E' Expression is in the medial wall.
Specimen S3F: embryonic day 18.5; Lrig1Gt(GST4169C6)Lex/Lrig1Gt(GST4169C6)Lex, Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: green - Lrig1; red - Myo7a (assay MGI:5790793).
Structure Level Pattern Image Note
TS26: cochlea Absent S3F' , S3F
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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