About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:202451 Del Rio T, et al., In vivo analysis of lrig genes reveals redundant and independent functions in the inner ear. PLoS Genet. 2013 Sep;9(9):e1003824
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5790359
Gene symbol: Lrig1
Gene name: leucine-rich repeats and immunoglobulin-like domains 1
Antibody: Lrig1 antibody
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 3A: embryonic day 12.5; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: green - Lrig1; red - Lrig2 reporter (assay MGI:5790348).
Structure Level Pattern Image Note
TS20: inner ear vestibular component Present Regionally restricted 3A , 3A' Expression is in the atrium.
TS20: cochlea Present 3A , 3A'
Specimen 3B: embryonic day 12.5; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: green - Lrig1; red - Lrig2 reporter (assay MGI:5790348).
Structure Level Pattern Image Note
TS20: inner ear vestibular component Present Regionally restricted 3B Expression is in the atrium.
Specimen 3C: embryonic day 12.5; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: green - Lrig1; red - Sox2 (assay MGI:5790361).
Structure Level Pattern Image Note
TS20: inner ear vestibular component Present Regionally restricted 3C' , 3C Expression is in the non-sensory areas of the atrium.
Specimen 3D: embryonic day 16.5; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: green - Lrig1; red - Sox2 (assay MGI:5790361).
Structure Level Pattern Image Note
TS24: utricle epithelium Present Regionally restricted 3D' , 3D Expression is in the transitional epithelium.
Specimen 3E: embryonic day 16.5; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: green - Lrig1; red - Lrig2 reporter (assay MGI:5790348).
Structure Level Pattern Image Note
TS24: inner ear vestibular component Present 3E
Specimen 3F: embryonic day 16.5; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: green - Lrig1; red - Sox2 (assay MGI:5790361).
Structure Level Pattern Image Note
TS24: macula of saccule Present Regionally restricted 3F' , 3F Expression is in the extramacular epithelium.
Specimen 3G: embryonic day 16.5; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: green - Lrig1; red - Lrig2 reporter (assay MGI:5790348).
Structure Level Pattern Image Note
TS24: inner ear vestibular component Present 3G
Specimen 3H: postnatal day 15; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: green - Lrig1; red - Lrig2 reporter (assay MGI:5790348).
Structure Level Pattern Image Note
TS28: cochlear ganglion Present 3H
TS28: inner ear vestibular component Present 3H
TS28: macula of saccule Present 3H
TS28: macula of utricle Present 3H
TS28: vestibular ganglion Present 3H
Specimen 3I: postnatal day 15; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Structure Level Pattern Image Note
TS28: utricle Present 3I
Specimen 3J: postnatal day 15; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Structure Level Pattern Image Note
TS28: saccule Present 3J
Specimen 3K'': postnatal day 15; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Structure Level Pattern Image Note
TS28: inner ear vestibular component Present 3K''
Specimen 4A: embryonic day 12.5; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Triple labeled: green - Lrig1; red - Lrig2 (assay MGI:5790348); blue - Nefh (assay. MGI:5790364).
Structure Level Pattern Image Note
TS20: cochlea epithelium Present Regionally restricted 4A'' , 4A Expression is in the non-sensory region.
TS20: inner ear mesenchyme Present Regionally restricted 4A , 4A'' Expression is in the mesenchyme surrounding the spiral ganglion.
Specimen 4B: embryonic day 16.5; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Triple labeled: green - Lrig1; red - Lrig2 (assay MGI:5790348); blue - Nefh (assay. MGI:5790364).
Structure Level Pattern Image Note
TS24: cochlea Present Regionally restricted 4B , 4B'' Expression is in the medial wall.
Specimen 4C: postnatal day 15; Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Triple labeled: green - Lrig1; red - Lrig2 (assay MGI:5790348); blue - Nefh (assay. MGI:5790364).
Structure Level Pattern Image Note
TS28: vestibular membrane Present Regionally restricted 4C'' , 4C Expression is at the base of Reissner's membrane at the cell surface.
TS28: cochlear ganglion Present 4C , 4C''
TS28: organ of Corti Present 4C , 4C''
Specimen S3A: embryonic day 18.5 (more )
Note: Double labeled: green - Lrig1; red - Myo7a (assay MGI:5790793).
Structure Level Pattern Image Note
TS26: saccule epithelium Present Regionally restricted S3A , S3A' Expression is in the non-sensory epithelium.
TS26: utricle epithelium Present Regionally restricted S3A , S3A' Expression is in the non-sensory epithelium.
Specimen S3B: embryonic day 18.5; Lrig1Gt(GST4169C6)Lex/Lrig1Gt(GST4169C6)Lex, Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: green - Lrig1; red - Myo7a (assay MGI:5790793).
Structure Level Pattern Image Note
TS26: saccule epithelium Absent S3B' , S3B
TS26: utricle epithelium Absent S3B' , S3B
Specimen S3C: embryonic day 18.5 (more )
Note: Double labeled: green - Lrig1; red - Myo7a (assay MGI:5790793).
Structure Level Pattern Image Note
TS26: inner ear Present Regionally restricted S3C , S3C' Expression is in projections to the utricle and lateral crista.
Specimen S3D: embryonic day 18.5; Lrig1Gt(GST4169C6)Lex/Lrig1Gt(GST4169C6)Lex, Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: green - Lrig1; red - Myo7a (assay MGI:5790793).
Structure Level Pattern Image Note
TS26: inner ear Absent S3D , S3D'
Specimen S3E: embryonic day 18.5 (more )
Note: Double labeled: green - Lrig1; red - Myo7a (assay MGI:5790793).
Structure Level Pattern Image Note
TS26: cochlea Present Regionally restricted S3E , S3E' Expression is in the medial wall.
Specimen S3F: embryonic day 18.5; Lrig1Gt(GST4169C6)Lex/Lrig1Gt(GST4169C6)Lex, Lrig2Gt(RST656)Byg/Lrig2+ (more )
Note: Double labeled: green - Lrig1; red - Myo7a (assay MGI:5790793).
Structure Level Pattern Image Note
TS26: cochlea Absent S3F' , S3F
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory