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Mir122 Gene Detail
Summary
  • Symbol
    Mir122
  • Name
    microRNA 122
  • Synonyms
    Mir122a, Mir122b, Mirn122a, Mirn122b, mmu-mir-122, mmu-mir-122a
Location &
Maps
more
  • Sequence Map
    Chr18:65381932-65381997 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18,
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    145 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676805
 miRNA gene Chr18:65381932-65381997 (+)
129S1/SvImJ ENSMUSG00200026280
 miRNA gene Chr18:62569322-62569387 (+)
A/J ENSMUSG00195032619
 miRNA gene Chr18:62614009-62614074 (+)
AKR/J ENSMUSG00220023067
 miRNA gene Chr18:62578077-62578142 (+)
BALB/cJ ENSMUSG00180012238
 miRNA gene Chr18:63180981-63181046 (+)
C3H/HeJ ENSMUSG00175010843
 miRNA gene Chr18:62785275-62785340 (+)
C57BL/6NJ ENSMUSG00215023811
 miRNA gene Chr18:62121880-62121945 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007605
 miRNA gene Chr18:61984379-61984444 (+)
CAST/EiJ ENSTCUG00005015906
 miRNA gene Chr18:61786741-61786806 (+)
CBA/J ENSMUSG00210032314
 miRNA gene Chr18:62743197-62743262 (+)
DBA/2J ENSMUSG00185030933
 miRNA gene Chr18:62649133-62649198 (+)
FVB/NJ ENSMUSG00205013182
 miRNA gene Chr18:62118115-62118180 (+)
JF1/MsJ ENSUMUG00000040662
 miRNA gene Chr18:62555741-62555806 (+)
LP/J ENSMUSG00230039531
 miRNA gene Chr18:64712207-64712272 (+)
NOD/ShiLtJ ENSMUSG00190008371
 miRNA gene Chr18:62387357-62387422 (+)
NZO/HlLtJ ENSMUSG00225030589
 miRNA gene Chr18:64597629-64597694 (+)
PWK/PhJ ENSLUMG00010026105
 miRNA gene Chr18:62955131-62955196 (+)
SPRET/EiJ ENSMSPG00010039789
 miRNA gene Chr18:63100401-63100466 (+)
WSB/EiJ ENSIUOG00005006347
 miRNA gene Chr18:62178679-62178744 (+)



Homology
more
  • Human Ortholog
    MIR122, microRNA 122
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR122, microRNA 122
  • Synonyms
    hsa-mir-122, mir-122, MIR122A, MIRN122, MIRN122A, miRNA122, miRNA122A
  • Links
    NCBI Gene ID: 406906

  • Chr Location
    chr18:58451074-58451158 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human MIR122 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    31 phenotypes from 3 alleles in 3 genetic backgrounds
    9 images
    18 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit steatohepatitis with fibrosis and hepatocellular carcinoma.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    649
  • Tissues
    18
  • Literature Summary
    16
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      27
    • RefSeq
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 387231 NCBI Gene Model | MGI Sequence Detail 66 C57BL/6J ±  kb
    transcript NR_029600 RefSeq | MGI Sequence Detail 66 ZRU/MplStud  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 9
      Primer pair 5
      Other 4
    Other Database
    Links
    less
    miRBase MI0000256
    Other
    Accession IDs
    less
    MGI:2676806
    References
    more
    • Summaries
      All 73
      Developmental Gene Expression 16
      Gene Ontology 7
      Phenotypes 18
    • Earliest
      J:84907 Lagos-Quintana M, et al., Identification of tissue-specific microRNAs from mouse. Curr Biol. 2002 Apr 30;12(9):735-9
    • Latest
      J:390841 Hunter RW, et al., SLAMseq reveals potential transfer of RNA from liver to kidney in the mouse. Nat Commun. 2025 Aug 11;16(1):7413
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory