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Ankrd49 Gene Detail
Summary
  • Symbol
    Ankrd49
  • Name
    ankyrin repeat domain 49
  • Synonyms
    Gbif
  • Feature Type
    protein coding gene
  • IDs
    MGI:1930842
    NCBI Gene: 56503
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:14690916-14695869 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 4.33 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    154 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1930842
 protein coding gene Chr9:14690914-14696152 (-)
129S1/SvImJ ENSMUSG00200044175
 protein coding gene Chr9:11592746-11597984 (-)
A/J ENSMUSG00195031712
 protein coding gene Chr9:11478313-11483551 (-)
AKR/J ENSMUSG00220027602
 protein coding gene Chr9:11455754-11460992 (-)
BALB/cJ ENSMUSG00180036353
 protein coding gene Chr9:11602206-11607444 (-)
C3H/HeJ ENSMUSG00175033602
 protein coding gene Chr9:11549242-11554480 (-)
C57BL/6NJ ENSMUSG00215028529
 protein coding gene Chr9:11543831-11549069 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031787
 protein coding gene Chr9:10986470-10989222 (-)
CAST/EiJ ENSTCUG00005026744
 protein coding gene Chr9:11578108-11583303 (-)
CBA/J ENSMUSG00210035823
 protein coding gene Chr9:11580198-11585436 (-)
DBA/2J ENSMUSG00185022496
 protein coding gene Chr9:11668917-11674155 (-)
FVB/NJ ENSMUSG00205027404
 protein coding gene Chr9:11652913-11658151 (-)
JF1/MsJ ENSUMUG00000042419
 protein coding gene Chr9:11651687-11656931 (-)
LP/J ENSMUSG00230038647
 protein coding gene Chr9:12090847-12096085 (-)
NOD/ShiLtJ ENSMUSG00190026592
 protein coding gene Chr9:11579438-11584676 (-)
NZO/HlLtJ ENSMUSG00225049828
 protein coding gene Chr9:11979643-11984881 (-)
PWK/PhJ ENSLUMG00010041077
 protein coding gene Chr9:11589940-11595182 (-)
SPRET/EiJ ENSMSPG00010021043
 protein coding gene Chr9:11773731-11778035 (-)
WSB/EiJ ENSIUOG00005043643
 protein coding gene Chr9:11247809-11253045 (-)



Homology
more
  • Human Ortholog
    ANKRD49, ankyrin repeat domain 49
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ANKRD49, ankyrin repeat domain 49
  • Synonyms
    FGIF, GBIF
  • Links
    NCBI Gene ID: 54851
    UniProt: Q8WVL7

  • Chr Location
    11q21; chr11:94493979-94499583 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    5
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    14
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 56503 NCBI Gene Model | MGI Sequence Detail 4954 C57BL/6J ±  kb
    transcript NM_001348260 RefSeq | MGI Sequence Detail 2453 C57BL/6  
    polypeptide Q8VE42 UniProt | EBI | MGI Sequence Detail 238 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 14
      cDNA 14

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2143287, MGI:2143429
    References
    more
    • Summaries
      All 36
      Gene Ontology 5
      Phenotypes 6
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:382398 Liu YH, et al., ANKRD49 promotes the invasion and metastasis of lung adenocarcinoma via a P38/ATF-2 signalling pathway. J Cell Mol Med. 2022 Aug;26(16):4401-4415
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory