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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Prkcd
protein kinase C, delta
MGI:97598
45 phenotypes from 7 alleles in 8 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
PrkcdM1Btlr/PrkcdM1Btlr
C57BL/6J-PrkcdM1Btlr
increased susceptibility to induced colitis J:265145
Prkcdm2Btlr/Prkcdm2Btlr
C57BL/6J-Prkcdm2Btlr
enhanced humoral immune response J:265146
increased IgM level J:265146
increased NK cell number J:265146
increased susceptibility to induced colitis J:265146
Prkcdtm1.1Chou/Prkcdtm1.1Chou
involves: C57BL/6 * C57BL/6NTac
abnormal neutrophil physiology J:217880
Prkcdtm1.1Khn/Prkcdtm1.1Khn
B6.129P2-Prkcdtm1.1Khn
improved glucose tolerance J:173902
increased insulin sensitivity J:173902
Prkcdtm1Kin/Prkcdtm1Kin
involves: 129P2/OlaHsd
abnormal bone ossification J:117333
abnormal osteoblast differentiation J:117333
decreased width of hypertrophic chondrocyte zone J:117333
Prkcdtm1Kin/Prkcdtm1Kin
involves: 129P2/OlaHsd * C57BL/6
abnormal immunoglobulin level J:143854
abnormal lymph node germinal center morphology J:76135
abnormal pancreatic beta cell morphology J:120293
abnormal Peyer's patch germinal center morphology J:76135
abnormal plasma cell differentiation J:143854
decreased body weight J:120293
decreased insulin secretion J:120293
enlarged lymph nodes J:76135
enlarged spleen J:76135
glomerulonephritis J:76135
impaired glucose tolerance J:120293
increased acute inflammation J:76135
increased anti-chromatin antibody level J:76135
increased B cell number J:76135
increased B cell proliferation J:76135, J:143854
increased follicular B cell number J:143854
increased IgA level J:76135, J:143854
increased IgG1 level J:76135, J:143854
increased IgM level J:143854
increased interleukin-6 secretion J:76135
increased marginal zone B cell number J:143854
increased spleen germinal center number J:76135
increased transitional stage B cell number J:143854
renal glomerular immunoglobulin deposits J:76135
Prkcdtm1Msg/Prkcdtm1Msg
involves: 129X1/SvJ * C57BL/6J
abnormal neutrophil physiology J:91377
abnormal response to CNS ischemic injury J:91377
decreased neutrophil cell number J:91377
Prkcdtm1Qxu/Prkcdtm1Qxu
B6.129P2-Prkcdtm1Qxu
decreased body weight J:173902
decreased liver triglyceride level J:173902
improved glucose tolerance J:173902
increased insulin sensitivity J:173902
premature death J:173902
Prkcdtm1Qxu/Prkcdtm1Qxu
involves: 129P2/OlaHsd
abnormal cardiovascular system physiology J:78680
abnormal response to transplant J:78680
arteriosclerosis J:78680
vascular smooth muscle hyperplasia J:78680
Prkcdtm1Qxu/Prkcdtm1Qxu
involves: 129P2/OlaHsd * C57BL/6
enlarged lymph nodes J:76134
enlarged spleen J:76134
normal immune system phenotype J:76134
increased anti-nuclear antigen antibody level J:76134
increased B cell apoptosis J:76134
increased B cell number J:76134
increased erythrocyte cell number J:76134
increased IgA level J:76134
increased IgG1 level J:76134
increased IgM level J:76134
premature death J:76134

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory