116 phenotypes from 9 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cd19tm1(cre)Cgn/Cd19+ Pbx1tm2Mlc/Pbx1tm2Mlc involves: 129P2/OlaHsd * 129S6/SvEvTac	no abnormal phenotype detected	J:132963
Nkx2-5tm2(cre)Rph/Nkx2-5+ Pbx1tm1.1Koss/Pbx1tm1.1Koss involves: 129P2/OlaHsd * 129S1/Sv	abnormal spleen morphology	J:184521
	spleen hypoplasia	J:184521
Pbx1em1Dunw/Pbx1em1Dunw C57BL/6J-Pbx1em1Dunw	abnormal primary sex determination	J:320934
	abnormal stomach position or orientation	J:320934
	adrenal gland hypoplasia	J:320934
	cleft secondary palate	J:320934
	decreased brain size	J:320934
	ectopic thymus	J:320934
	esophageal atresia	J:320934
	eyelids open at birth	J:320934
	hunched posture	J:320934
	larynx stenosis	J:320934
	liver hypoplasia	J:320934
	pelvic kidney	J:320934
	persistent truncus arteriosus	J:320934
	pulmonary hypoplasia	J:320934
	spleen hypoplasia	J:320934
	stomach hypoplasia	J:320934
	subcutaneous edema	J:320934
	thymus hypoplasia	J:320934
	trachea occlusion	J:320934
	umbilical hernia	J:320934
	ventricular septal defect	J:320934
Pbx1tm1.1Febe/Pbx1+ involves: C57BL/6	abnormal response/metabolism to endogenous compounds	J:129552
	decreased adrenal gland zona fasciculata size	J:129552
	small adrenal glands	J:129552
Pbx1tm1.1Febe/Pbx1tm1.1Febe involves: C57BL/6	abnormal embryonic growth/weight/body size	J:129552
	abnormal limb morphology	J:129552
	abnormal vasculogenesis	J:129552
	hunched posture	J:129552
	pallor	J:129552
	skin edema	J:129552
Pbx1tm1.1Koss/Pbx1tm1.1Koss Tg(WT1-cre)AG11Dbdr/0 involves: 129P2/OlaHsd * C57BL/6	spleen hypoplasia	J:184521
Pbx1tm1.1Koss/Pbx1tm1.2Koss Tmem163Tg(ACTB-cre)2Mrt/0 involves: 129P2/OlaHsd * FVB/N	abnormal deltoid tuberosity morphology	J:184521
	abnormal humerus morphology	J:184521
	abnormal rib morphology	J:184521
	abnormal scapula morphology	J:184521
	absent spleen	J:184521
	rib fusion	J:184521
	scapular bone hypoplasia	J:184521
	short ribs	J:184521
Pbx1tm1Koss/Pbx1tm1Koss Nkx2-5tm2(cre)Rph/Nkx2-5+ involves: 129P2/OlaHsd * 129S1/Sv	abnormal spleen mesenchyme morphology	J:184521
	abnormal spleen morphology	J:184521
	spleen hypoplasia	J:184521
Pbx1tm1Mlc/Pbx1+ involves: 129S6/SvEvTac * C57BL/6	abnormal pancreatic islet morphology	J:75811
	decreased body size	J:70684
	decreased insulin secretion	J:75811
	impaired glucose tolerance	J:75811
	increased insulin sensitivity	J:75811
Pbx1tm1Mlc/Pbx1tm1Mlc involves: 129S6/SvEvTac	edema	J:178316
	palatal shelf hypoplasia	J:178316
	small snout	J:178316
Pbx1tm1Mlc/Pbx1tm1Mlc involves: 129S6/SvEvTac * C57BL/6	abnormal axial skeleton morphology	J:71996
	abnormal clavicle morphology	J:71996
	abnormal craniofacial bone morphology	J:71996
	abnormal developmental patterning	J:71996
	abnormal dorsal-ventral axis patterning	J:71996
	abnormal embryonic growth/weight/body size	J:71996
	abnormal embryonic tissue morphology	J:71996
	abnormal gonad rudiment morphology	J:87270
	abnormal hyoid bone lesser horn morphology	J:71996
	abnormal kidney cortex morphology	J:82126
	abnormal kidney medulla morphology	J:82126
	abnormal left-right axis symmetry of the somites	J:71996
	abnormal limb bone morphology	J:71996
	abnormal limb bud morphology	J:71996
	abnormal malleus morphology	J:71996
	abnormal metanephric mesenchyme morphology	J:82126
	abnormal metanephros morphology	J:82126
	abnormal middle ear ossicle morphology	J:71996
	abnormal nephrogenic mesenchyme morphogenesis	J:82126
	abnormal nephrogenic zone morphology	J:82126
	abnormal outer ear morphology	J:71996
	abnormal pelvic girdle bone morphology	J:71996
	abnormal proximal-distal axis patterning	J:71996
	abnormal scapula morphology	J:71996
	abnormal second pharyngeal arch morphology	J:71996
	abnormal styloid process morphology	J:71996
	abnormal ureteric bud elongation	J:82126
	absent adrenal gland	J:87270
	absent common myeloid progenitor cells	J:70684
	absent oval window	J:71996
	absent pancreatic islets	J:75811
	absent spleen	J:70684, J:71996
	absent stapes	J:71996
	anemia	J:70684
	decreased chondrocyte proliferation	J:71996
	decreased hematocrit	J:70684
	decreased nephron number	J:82126
	decreased renal glomerulus number	J:82126
	delayed kidney development	J:82126
	diaphragmatic hernia	J:182007
	ectopic kidney	J:71996, J:82126
	ectopic thymus	J:71996
	exocrine pancreas hypoplasia	J:75811
	impaired branching involved in ureteric bud morphogenesis	J:82126
	impaired hematopoiesis	J:70684
	lethality throughout fetal growth and development, complete penetrance	J:70684
	liver hypoplasia	J:71996
	low mean erythrocyte cell number	J:70684
	outer ear hypoplasia	J:71996
	pallor	J:71996
	premature chondrocyte differentiation	J:71996
	pulmonary hypoplasia	J:71996
	renal hypoplasia	J:82126
	short styloid process	J:71996
	single kidney	J:82126
	skin edema	J:70684
	small kidney	J:82126
	stomach hypoplasia	J:71996
Pbx1tm1Mlc/Pbx1tm2.1Mlc involves: 129S6/SvEvTac	abnormal liver development	J:132963
	abnormal lymph node primary follicle morphology	J:132963
	decreased CD4-positive, alpha-beta T cell number	J:132963
	decreased CD8-positive, alpha-beta T cell number	J:132963
	decreased mature B cell number	J:132963
	lethality throughout fetal growth and development, complete penetrance	J:132963
Pbx1tm1Mlc/Pbx1tm3.1Mlc Tg(Mx1-cre)1Cgn/0 involves: 129S6/SvEvTac * C57BL/6 * CBA	abnormal common lymphocyte progenitor cell morphology	J:149799
	abnormal definitive hematopoiesis	J:149799
	abnormal hematopoietic stem cell morphology	J:149799
	decreased hematopoietic stem cell number	J:149799
Pbx1tm1Mlc/Pbx1tm3.1Mlc Tg(Tek-cre)1Ywa/0 involves: 129S6/SvEvTac * C57BL/6 * SJL	abnormal common lymphocyte progenitor cell morphology	J:149799
	abnormal definitive hematopoiesis	J:149799
	abnormal hematopoietic stem cell morphology	J:149799
	abnormal spleen morphology	J:149799
	abnormal thymus morphology	J:149799
	decreased B cell number	J:149799
	decreased bone marrow cell number	J:149799
	decreased common myeloid progenitor cell number	J:149799
	decreased double-negative T cell number	J:149799
	decreased hematopoietic stem cell number	J:149799
	decreased pre-B cell number	J:149799
	decreased pro-B cell number	J:149799
	decreased T cell number	J:149799
	small spleen	J:149799
	small thymus	J:149799
	spleen hypoplasia	J:149799
	thymus hypoplasia	J:149799