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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Blnk
B cell linker
MGI:96878
39 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Blnktm1Achn/Blnk+
Btktm1Wk/Btktm1Wk
Tg(IGH-Btk)1Witt/0
involves: 129S4/SvJae * 129X1/SvJ * BALB/c * C3H * C57BL/6 		abnormal B cell physiology J:82430
decreased B cell proliferation J:82430
Blnktm1Dkit/Blnktm1Dkit
Cd19tm1(cre)Cgn/Cd19tm1(cre)Cgn
involves: 129P2/OlaHsd * C57BL/6 * NZB 		abnormal pre-B cell morphology J:84040
absent immature B cells J:84040
absent mature B cells J:84040
arrested B cell differentiation J:84040
decreased pre-B cell number J:84040
enlarged lymph nodes J:84040
enlarged spleen J:84040
increased leukemia incidence J:84040
Blnktm1Dkit/Blnktm1Dkit
Igh-Jtm1(3H9-VDJ)Mwg/Igh-J+
involves: C57BL/6 * NZB 		abnormal immature B cell morphology J:94297
Blnktm1Dkit/Blnktm1Dkit
Igh-Jtm1(3H9-VDJ)Mwg/Igh-J+
Igk-Jtm1Mwg/Igk-J+
involves: C57BL/6 * NZB 		abnormal immature B cell morphology J:94297
Blnktm1Dkit/Blnktm1Dkit
Prkcdtm1Kin/Prkcdtm1Kin
involves: 129P2/OlaHsd * C57BL/6 * NZB 		abnormal B cell proliferation J:143854
abnormal immunoglobulin level J:143854
abnormal plasma cell differentiation J:143854
arrested B cell differentiation J:143854
decreased B-1 B cell number J:143854
decreased B-2 B cell number J:143854
decreased follicular B cell number J:143854
decreased marginal zone B cell number J:143854
increased B cell apoptosis J:143854
increased IgA level J:143854
increased IgG1 level J:143854
increased IgG2b level J:143854
increased IgG3 level J:143854
increased IgM level J:143854
Blnktm1Kplm/Blnktm1Kplm
Ightm4Cgn/Igh+
Igktm1Rsky/Igk+
involves: 129P2/OlaHsd 		abnormal B cell differentiation J:120460
decreased B cell number J:120460
increased pre-B cell number J:120460
increased transitional stage B cell number J:120460
Blnktm1Kplm/Blnktm1Kplm
Plcg2tm1.1Kuro/Plcg2+
involves: 129P2/OlaHsd 		abnormal B cell activation J:131161
decreased B cell number J:131161
increased B cell apoptosis J:131161
Blnktm1Kplm/Blnktm1Kplm
Plcg2tm1.1Kuro/Plcg2tm1.1Kuro
involves: 129P2/OlaHsd 		decreased B cell number J:131161
increased B cell apoptosis J:131161
perinatal lethality, incomplete penetrance J:131161
spleen hypoplasia J:131161
Blnktm1Pjln/Blnktm1Pjln
Btktm1Gsv/Y
involves: 129P2/OlaHsd * BALB/c * C57BL/6 		abnormal B cell differentiation J:94768
decreased IgG3 level J:94768
decreased IgM level J:94768
decreased immature B cell number J:94768
decreased immunoglobulin level J:94768
decreased mature B cell number J:94768
increased B cell derived lymphoma incidence J:94768
Blnktm1Pjln/Blnktm1Pjln
Btktm1Gsv/Y
Tg(CD19-BTK*K430R)XK24Rwhe/?
involves: 129P2/OlaHsd * BALB/c * C57BL/6 * FVB 		abnormal B cell differentiation J:94768
decreased IgG3 level J:94768
decreased IgM level J:94768
decreased immunoglobulin level J:94768
normal neoplasm J:94768
Blnktm1Pjln/Blnktm1Pjln
Btktm1Wk/Btktm1Wk
involves: 129S4/SvJae * BALB/c * C57BL/6 		arrested B cell differentiation J:70406
Blnktm1Pjln/Blnktm1Pjln
Cd79atm1(cre)Reth/Cd79atm1(cre)Reth
Mzb1tm1.1Rug/Mzb1tm1.1Rug
involves: 129S2/SvPas * BALB/c * C57BL/6 * SJL 		abnormal bone marrow cell physiology J:211639
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory