Itgb2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Itgb2
integrin beta 2
MGI:96611

12 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Itgav^tm1Blb/Itgav^tm1Blb Itgb1^tm1Ref/Itgb1^tm1Ref Itgb2^tm2Bay/Itgb2^tm2Bay Itgb7^tm1Cgn/Itgb7^tm1Cgn Tg(Mx1-cre)1Cgn/0 involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 * CBA	abnormal cellular extravasation	J:134784
	abnormal dendritic cell physiology	J:134784
	normal immune system phenotype	J:134784
Itgb2^tm1Bay/Itgb2^tm1Bay Psrs1^PL/J/Psrs1^PL/J B6.Cg-(D10Mit75-D10Mit271) Itgb2^tm1Bay	psoriasis	J:134251
	rheumatoid arthritis	J:134251
Itgb2^tm1Bay/Itgb2^tm1Bay Psrs1^PL/J/Psrs1^PL/J B6.Cg-(D10Mit126-D10Mit38) Itgb2^tm1Bay	psoriasis	J:134251
	rheumatoid arthritis	J:134251
Itgb2^tm1Bay/? Psrs1^PL/J/? involves: 129S7/SvEvBrd * C57BL/6J * PL/J	psoriasis	J:117544
Itgb2^tm1Bay/? Psrs2^PL/J/? involves: 129S7/SvEvBrd * C57BL/6J * PL/J	psoriasis	J:117544
Itgb2^tm1Bay/? Psrs3^PL/J/? involves: 129S7/SvEvBrd * C57BL/6J * PL/J	psoriasis	J:117544
Itgb2^tm1Bay/? Psrs4^PL/J/? involves: C57BL/6J * PL/J	psoriasis	J:117544
Itgb2^tm1Bay/? Psrs4^PL/J/Psrs4^PL/J Psrs6^PL/J/Psrs6^PL/J involves: C57BL/6J * PL/J	psoriasis	J:117544
Itgb2^tm1Bay/? Psrs5^PL/J/? involves: 129S7/SvEvBrd * C57BL/6J * PL/J	psoriasis	J:117544
Itgb2^tm1Bay/? Psrs7^PL/J/? involves: 129S7/SvEvBrd * C57BL/6J * PL/J	psoriasis	J:117544
Ptpn6^me-v/Ptpn6^me-v involves: 129S7/SvEvBrd * C57BL/6J	decreased retina photoreceptor cell number	J:108375
Ptpn6^me-v/Ptpn6^me-v involves: 129S7/SvEvBrd * C57BL/6J	retina photoreceptor degeneration	J:108375
Rhoh^tm1Brak/Rhoh^tm1Brak Itgb2^tm2Bay/Itgb2^tm2Bay involves: 129/Sv * C57BL/6	decreased CD4-positive, alpha-beta T cell number	J:143161
	decreased CD8-positive, alpha-beta T cell number	J:143161
	decreased double-positive T cell number	J:143161
	decreased single-positive T cell number	J:143161
	increased double-negative T cell number	J:143161

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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