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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Itgb2
integrin beta 2
MGI:96611
12 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Itgavtm1Blb/Itgavtm1Blb
Itgb1tm1Ref/Itgb1tm1Ref
Itgb2tm2Bay/Itgb2tm2Bay
Itgb7tm1Cgn/Itgb7tm1Cgn
Tg(Mx1-cre)1Cgn/0
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 * CBA
abnormal cellular extravasation J:134784
abnormal dendritic cell physiology J:134784
normal immune system phenotype J:134784
Itgb2tm1Bay/Itgb2tm1Bay
Psrs1PL/J/Psrs1PL/J
B6.Cg-(D10Mit75-D10Mit271) Itgb2tm1Bay
psoriasis J:134251
rheumatoid arthritis J:134251
Itgb2tm1Bay/Itgb2tm1Bay
Psrs1PL/J/Psrs1PL/J
B6.Cg-(D10Mit126-D10Mit38) Itgb2tm1Bay
psoriasis J:134251
rheumatoid arthritis J:134251
Itgb2tm1Bay/?
Psrs1PL/J/?
involves: 129S7/SvEvBrd * C57BL/6J * PL/J
psoriasis J:117544
Itgb2tm1Bay/?
Psrs2PL/J/?
involves: 129S7/SvEvBrd * C57BL/6J * PL/J
psoriasis J:117544
Itgb2tm1Bay/?
Psrs3PL/J/?
involves: 129S7/SvEvBrd * C57BL/6J * PL/J
psoriasis J:117544
Itgb2tm1Bay/?
Psrs4PL/J/?
involves: C57BL/6J * PL/J
psoriasis J:117544
Itgb2tm1Bay/?
Psrs4PL/J/Psrs4PL/J
Psrs6PL/J/Psrs6PL/J
involves: C57BL/6J * PL/J
psoriasis J:117544
Itgb2tm1Bay/?
Psrs5PL/J/?
involves: 129S7/SvEvBrd * C57BL/6J * PL/J
psoriasis J:117544
Itgb2tm1Bay/?
Psrs7PL/J/?
involves: 129S7/SvEvBrd * C57BL/6J * PL/J
psoriasis J:117544
Ptpn6me-v/Ptpn6me-v
involves: 129S7/SvEvBrd * C57BL/6J
decreased retinal photoreceptor cell number J:108375
retinal photoreceptor degeneration J:108375
Rhohtm1Brak/Rhohtm1Brak
Itgb2tm2Bay/Itgb2tm2Bay
involves: 129/Sv * C57BL/6
decreased CD4-positive, alpha beta T cell number J:143161
decreased CD8-positive, alpha-beta T cell number J:143161
decreased double-positive T cell number J:143161
decreased single-positive T cell number J:143161
increased double-negative T cell number J:143161

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/19/2020
MGI 6.15
The Jackson Laboratory