About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Itgb1
integrin beta 1 (fibronectin receptor beta)
MGI:96610
39 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Cdkn1atm1Tyj/Cdkn1atm1Tyj
Itgb1tm1Mll/Itgb1tm1Mll
Tg(Wap-cre)1Gsc/0
involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 * FVB/N 		abnormal mammary gland growth during lactation J:99405
Itgavtm1Blb/Itgavtm1Blb
Itgb1tm1Ref/Itgb1tm1Ref
Itgb2tm2Bay/Itgb2tm2Bay
Itgb7tm1Cgn/Itgb7tm1Cgn
Tg(Mx1-cre)1Cgn/0
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 * CBA 		abnormal cellular extravasation J:134784
abnormal dendritic cell physiology J:134784
normal immune system phenotype J:134784
Itgb1tm1Ehi/Itgb1tm1Ehi
either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) 		abnormal cardiac mesenchyme morphology J:76216
abnormal cell cycle J:76216
abnormal craniofacial morphology J:76216
abnormal embryo development J:76216
abnormal heart morphology J:76216
decreased cell proliferation J:76216
decreased embryo size J:76216
decreased fibroblast proliferation J:76216
delayed somite formation J:76216
embryonic growth retardation J:76216
embryonic lethality during organogenesis, complete penetrance J:76216
exencephaly J:76216
failure of chorioallantoic fusion J:76216
hemorrhage J:76216
increased apoptosis J:76216
kinked neural tube J:76216
pericardial effusion J:76216
wavy neural tube J:76216
Itgb1tm1Mll/Itgb1tm1Mll
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
Tg(Nes-cre/Esr1*)1Kuan/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB 		abnormal Bergmann glial cell morphology J:191222
abnormal cerebellar foliation J:191222
abnormal cerebellum external granule cell layer morphology J:191222
abnormal cerebellum fissure morphology J:191222
abnormal cerebellum lobule morphology J:191222
ectopic cerebellar granule cells J:191222
Itgb1tm1Mll/Itgb1tm1Mll
Tg(MMTV-cre)7Mul/0
Tg(MMTV-PyVT)634Mul/0
involves: 129X1/SvJ * FVB/N 		decreased mammary gland tumor incidence J:92547
Itgb1tm1Ref/Itgb1tm1Ref
Tg(Ins2-cre)1Heed/?
Tg(RIP1-Tag)2Dh/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * CBA * DBA/2J 		abnormal cell adhesion J:122649
abnormal cell death J:122649
abnormal cell morphology J:122649
abnormal mitosis J:122649
abnormal tumor susceptibility J:122649
decreased metastatic potential J:122649
early cellular replicative senescence J:122649
Itgb1tm1Ref/Itgb1tm1Ref
Tg(RIP1-Tag)2Dh/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J 		abnormal tumor morphology J:122649
Itgb1tm4Ref/Itgb1tm4Ref
Tg(Ins2-cre)1Heed/?
Tg(RIP1-Tag)2Dh/?
involves: C57BL/6 * C57BL/6J * CBA * DBA/2J 		abnormal tumor susceptibility J:122649
Itgb1tm11.1Ref/Itgb1tm11.1Ref
Tg(KRT5-SRC)CJdg/0
involves: 129S1/Sv * 129X1/SvJ * FVB/N 		normal integument phenotype J:176453
normal neoplasm J:176453
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory