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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Mirc1
microRNA cluster 1, including Mir17 through Mir92-1
MGI:3790484
28 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Bmp4tm1Jfm/Bmp4tm1Jfm
Mirc1tm1.2Tyj/Mirc1tm1.2Tyj
Tg(Mef2c-cre)2Blk/0
involves: 129S4/SvJaeSor * C57BL/6
abnormal cardiac outflow tract development J:169047
abnormal truncus arteriosus septation J:169047
Mirc1tm1.1Tyj/Mirc1tm1.1Tyj
Pkd1tm1.1Pcha/Pkd1tm1.1Pcha
Tg(Cdh16-cre)91Igr/0
involves: 129 * 129S4/SvJae * C57BL/6 * ICR
decreased blood urea nitrogen level J:244067
normal renal/urinary system phenotype J:244067
Mirc1tm1.1Tyj/Mirc1tm1.1Tyj
Pkd1tm1.1Pcha/Pkd1tm2Som
Tg(Cdh16-cre)91Igr/0
involves: 129 * 129S4/SvJae * C57BL/6 * ICR
abnormal peroxisome morphology J:244067
abnormal redox activity J:244067
decreased circulating creatinine level J:244067
decreased kidney cell proliferation J:244067
decreased kidney weight J:244067
increased fatty acid oxidation J:244067
kidney cyst J:244067
normal renal/urinary system phenotype J:244067
Mirc1tm1.1Tyj/Mirc1tm1.1Tyj
Pkd1tm2Som/Pkd1tm2Som
Tg(Cdh16-cre)91Igr/0
involves: 129S4/SvJae * C57BL/6 * ICR
decreased circulating creatinine level J:244067
decreased kidney cell proliferation J:244067
decreased kidney weight J:244067
premature death J:244067
Mirc1tm1.1Tyj/Mirc1tm1.1Tyj
Pkd2tm3Som/Pkd2tm3Som
Tg(Pkhd1-cre)1Igr/0
involves: 129S4/SvJae * C57BL/6
decreased circulating creatinine level J:244067
decreased kidney cell proliferation J:244067
kidney cyst J:244067
premature death J:244067
Mirc1tm2.1Aven/Mirc1+
Tg(IghMyc)22Bri/?
involves: 129S4/SvJae * C57BL/6 * SJL/J
abnormal survival J:223213
Mirc1tm2.1Aven/Mirc1tm2.1Aven
Tg(ARR2/Pbsn-MYC)7Key/0
involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL/J
decreased prostate gland tumor incidence J:223213
increased prostate gland adenocarcinoma incidence J:223213
small prostate gland J:223213
Mirc1tm2.1Aven/Mirc1tm2.1Aven
Tg(IghMyc)22Bri/?
involves: 129S4/SvJae * C57BL/6 * SJL/J
abnormal pre-B cell morphology J:223213
abnormal survival J:223213
increased B cell apoptosis J:223213
increased B cell derived lymphoma incidence J:223213
increased tumor latency J:223213
Mirc2tm1.1Tyj/Y
Mirc3tm1.1Tyj/Mirc3+
Mirc1tm1.2Tyj/Mirc1+
involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL
no abnormal phenotype detected J:134861
Mirc2tm1.1Tyj/Y
Mirc3tm1.1Tyj/Mirc3tm1.1Tyj
Mirc1tm1.2Tyj/Mirc1+
involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL
no abnormal phenotype detected J:134861
Mirc2tm1.1Tyj/Y
Mirc3tm1.1Tyj/Mirc3tm1.1Tyj
Mirc1tm1.2Tyj/Mirc1tm1.2Tyj
involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL
atrial septal defect J:134861
increased apoptosis J:134861
prenatal lethality, complete penetrance J:134861
thin ventricular wall J:134861
ventricular septal defect J:134861
Mirc3tm1.1Tyj/Mirc3tm1.1Tyj
Mirc1tm1.2Tyj/Mirc1+
involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL
no abnormal phenotype detected J:134861
Mirc3tm1.1Tyj/Mirc3tm1.1Tyj
Mirc1tm1.2Tyj/Mirc1tm1.2Tyj
involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL
atrial septal defect J:134861
blood vessel congestion J:134861
edema J:134861
increased apoptosis J:134861
prenatal lethality, complete penetrance J:134861
thin ventricular wall J:134861
ventricular septal defect J:134861

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/17/2022
MGI 6.19
The Jackson Laboratory