Pkd2^tm3Som
Targeted Allele Detail

Summary

• Symbol: Pkd2^tm3Som
• Name: polycystin 2, transient receptor potential cation channel; targeted mutation 3, Stefan Somlo
• MGI ID: MGI:5430797
• Gene: Pkd2 Location: Chr5:104607316-104653685 bp, + strand Genetic Position: Chr5, 50.68 cM
• Alliance: Pkd2^tm3Som page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:185863
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exons 3 and 4 were flanked by loxP sites. (J:185863)

Disease models

Expression

In Mice Carrying this Mutation:	104041 assay results 5 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pkd2 Mutation: 84 strains or lines available

References

• Original: J:185863 Nishio S, et al., Loss of oriented cell division does not initiate cyst formation. J Am Soc Nephrol. 2010 Feb;21(2):295-302
• All: 24 reference(s)