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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Mirc1
microRNA cluster 1, including Mir17 through Mir92-1
MGI:3790484
44 phenotypes from 9 alleles in 12 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Mirc1tm1.1Aven/Mirc1+
B6.Cg-Mirc1tm1.1Aven
brachyphalangia J:223213
vertebral fusion J:223213
Mirc1tm1.1Aven/Mirc1tm1.1Aven
B6.Cg-Mirc1tm1.1Aven
abnormal rostral-caudal axis patterning J:223213
brachyphalangia J:223213
delayed bone ossification J:223213
fused carpal bones J:223213
lumbar vertebral transformation J:223213
perinatal lethality, incomplete penetrance J:223213
thoracic vertebral transformation J:223213
vertebral fusion J:223213
Mirc1tm1.1Aven/Mirc1tm1.1Aven
involves: 129S4/SvJae * C57BL/6 * SJL/J
decreased alpha-beta T cell number J:223213
decreased B cell number J:223213
decreased body weight J:223213
decreased myeloid cell number J:223213
decreased pre-B cell number J:223213
decreased pro-B cell number J:223213
increased B cell apoptosis J:223213
small spleen J:223213
Mirc1tm1.1Tyj/Mirc1tm1.1Tyj
involves: 129S4/SvJae * C57BL/6 * SJL
no abnormal phenotype detected J:134861
Mirc1tm1.2Tyj/Mirc1+
B6.Cg-Mirc1tm1.2Tyj
brachyphalangia J:223213
fused carpal bones J:223213
lumbar vertebral transformation J:223213
Mirc1tm1.2Tyj/Mirc1+
involves: 129S4/SvJae * C57BL/6
brachyphalangia J:188762
decreased body size J:188762
decreased body weight J:223213
microcephaly J:188762
Mirc1tm1.2Tyj/Mirc1+
involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL
decreased body size J:134861
Mirc1tm1.2Tyj/Mirc1tm1.2Tyj
B6.Cg-Mirc1tm1.2Tyj
abnormal phalanx morphology J:223213
abnormal rostral-caudal axis patterning J:223213
cleft palate J:223213
delayed bone ossification J:223213
fused carpal bones J:223213
lumbar vertebral transformation J:223213
perinatal lethality, complete penetrance J:223213
syndactyly J:223213
thoracic vertebral transformation J:223213
vertebral fusion J:223213
vertebral transformation J:223213
Mirc1tm1.2Tyj/Mirc1tm1.2Tyj
involves: 129S4/SvJae * C57BL/6
abnormal forelimb zeugopod morphology J:188762
abnormal hindlimb zeugopod morphology J:188762
abnormal phalanx morphology J:188762
brachyphalangia J:188762
cervical vertebral fusion J:188762
decreased heart right ventricle size J:169047
delayed endochondral bone ossification J:188762
delayed intramembranous bone ossification J:188762
double outlet right ventricle J:169047
fused carpal bones J:188762
microcephaly J:188762
perinatal lethality, complete penetrance J:223213
pulmonary hypoplasia J:223213
ventricular septal defect J:169047, J:223213
Mirc1tm1.2Tyj/Mirc1tm1.2Tyj
involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL
abnormal B cell differentiation J:134861
abnormal interventricular septum morphology J:134861
decreased embryo size J:134861
decreased embryo weight J:134861
decreased pre-B cell number J:134861
increased B cell apoptosis J:134861
neonatal lethality, complete penetrance J:134861
pulmonary hypoplasia J:134861
Mirc1tm1.3Tyj/Mirc1tm1.3Tyj
involves: 129S4/SvJae * C57BL/6 * FVB/N
abnormal B cell differentiation J:134861
abnormal interventricular septum morphology J:134861
decreased embryo size J:134861
decreased embryo weight J:134861
decreased pre-B cell number J:134861
increased B cell apoptosis J:134861
neonatal lethality, complete penetrance J:134861
pulmonary hypoplasia J:134861
Mirc1tm1Tyj/Mirc1tm1Tyj
Tg(Mx1-cre)1Cgn/0
involves: 129S4/SvJae * C57BL/6 * CBA * SJL
abnormal immunoglobulin heavy chain V(D)J recombination J:134861
decreased pre-B cell number J:134861
increased B cell apoptosis J:134861
Mirc1tm2.1Aven/Mirc1tm2.1Aven
B6.Cg-Mirc1tm2.1Aven
perinatal lethality, incomplete penetrance J:223213
vertebral fusion J:223213
Mirc1tm2.1Aven/Mirc1tm2.1Aven
involves: 129S4/SvJae * C57BL/6 * SJL/J
decreased B cell number J:223213
decreased myeloid cell number J:223213
Mirc1tm3.1Aven/Mirc1+
B6.Cg-Mirc1tm3.1Aven
brachyphalangia J:223213
Mirc1tm3.1Aven/Mirc1+
involves: 129S4/SvJae * C57BL/6 * SJL/J
decreased body weight J:223213
Mirc1tm3.1Aven/Mirc1tm3.1Aven
B6.Cg-Mirc1tm3.1Aven
abnormal rostral-caudal axis patterning J:223213
brachyphalangia J:223213
delayed bone ossification J:223213
fused carpal bones J:223213
lumbar vertebral transformation J:223213
perinatal lethality, incomplete penetrance J:223213
thoracic vertebral transformation J:223213
vertebral fusion J:223213
vertebral transformation J:223213
Mirc1tm3.1Aven/Mirc1tm3.1Aven
involves: 129S4/SvJae * C57BL/6 * SJL/J
decreased alpha-beta T cell number J:223213
decreased B cell number J:223213
decreased body weight J:223213
decreased myeloid cell number J:223213
decreased pre-B cell number J:223213
decreased pro-B cell number J:223213
increased B cell apoptosis J:223213
small spleen J:223213
Mirc1tm4.1Aven/Mirc1+
B6.Cg-Mirc1tm4.1Aven
brachyphalangia J:223213
Mirc1tm4.1Aven/Mirc1+
involves: 129S4/SvJae * C57BL/6 * SJL/J
decreased body weight J:223213
Mirc1tm4.1Aven/Mirc1tm4.1Aven
B6.Cg-Mirc1tm4.1Aven
abnormal phalanx morphology J:223213
cleft palate J:223213
delayed bone ossification J:223213
fused carpal bones J:223213
lumbar vertebral transformation J:223213
perinatal lethality, complete penetrance J:223213
thoracic vertebral transformation J:223213
vertebral fusion J:223213
Mirc1tm4.1Aven/Mirc1tm4.1Aven
involves: 129S4/SvJae * C57BL/6 * SJL/J
perinatal lethality, complete penetrance J:223213
pulmonary hypoplasia J:223213
Tg(Sftpc-Mirn17-92)1Blh/0
involves: FVB * ICR
abnormal lung development J:128019
abnormal lung morphology J:128019
abnormal pulmonary alveolus morphology J:128019
atelectasis J:128019
perinatal lethality, incomplete penetrance J:128019
pulmonary hyperplasia J:128019

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/17/2022
MGI 6.19
The Jackson Laboratory