76 phenotypes from 7 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Megf8b2b288Clo/Megf8b2b288Clo C57BL/6J-Megf8b2b288Clo	anophthalmia	J:175213
	cleft palate	J:175213
	complete atrioventricular septal defect	J:175213
	d-loop transposition of the great arteries	J:175213
	dextrocardia	J:175213
	double outlet right ventricle, ventricular defect committed to aorta	J:175213
	heterotaxia	J:175213
	micrognathia	J:175213
	short snout	J:175213
Megf8b2b1702.2Clo/Megf8b2b1702.2Clo C57BL/6J-Megf8b2b1702.2Clo	anophthalmia	J:175213
	atrioventricular septal defect	J:175213
	cleft palate	J:175213
	coronary fistula	J:175213
	decreased body size	J:175213
	dextrocardia	J:175213
	double outlet right ventricle	J:175213
	double outlet right ventricle, Taussig bing type	J:175213
	double outlet right ventricle, ventricular defect committed to aorta	J:175213
	heterotaxia	J:175213
	micrognathia	J:175213
	microphthalmia	J:175213
	muscular ventricular septal defect	J:175213
	omphalocele	J:175213
	petechiae	J:175213
	right pulmonary isomerism	J:175213
	right-sided stomach	J:175213
	short snout	J:175213
	spleen hypoplasia	J:175213
	thymus hypoplasia	J:175213
	transposition of great arteries	J:175213
Megf8Gt(G037A09)Wrst/Megf8Gt(G037A09)Wrst involves: 129S6/SvEvTac * C57BL/6J	abnormal atrioventricular valve morphology	J:206541
	abnormal autopod morphology	J:206541
	abnormal cardiac outflow tract development	J:206541
	abnormal direction of embryo turning	J:206541
	abnormal direction of heart looping	J:206541
	abnormal heart atrium morphology	J:206541
	abnormal mitral valve morphology	J:206541
	abnormal thoracic cage morphology	J:206541
	abnormal tricuspid valve morphology	J:206541
	atrial septal defect	J:206541
	normal cardiovascular system phenotype	J:206541
	delayed bone ossification	J:206541
	edema	J:206541
	heart right ventricle outflow tract stenosis	J:206541
	lethality throughout fetal growth and development, complete penetrance	J:206541
	preaxial polydactyly	J:206541
	split sternum	J:206541
	ventricular septal defect	J:206541
Megf8Gt(G037A09)Wrst/Megf8m687Ddg involves: 129S6/SvEvTac * C3H/He * C57BL/6 * C57BL/6J	abnormal axon fasciculation	J:206541
	abnormal ophthalmic nerve morphology	J:206541
	abnormal trigeminal nerve morphology	J:206541
Megf8hlb611/Megf8hlb611 involves: C57BL/6J	abdominal situs abnormality	J:311933
	abnormal cardiac outflow tract development	J:146805
	abnormal direction of embryo turning	J:146805
	abnormal direction of heart looping	J:146805
	abnormal heart position or orientation	J:311933
	abnormal heart septum morphology	J:311933
	absent spleen	J:146805
	accessory spleen	J:146805
	anomalous pulmonary venous connection	J:146805
	atrioventricular septal defect	J:311933
	dextrocardia	J:146805, J:311933
	normal embryo phenotype	J:146805
	normal hematopoietic system phenotype	J:146805
	heterotaxia	J:146805, J:311933
	lung situs inversus	J:311933
	mesocardia	J:146805, J:311933
	preaxial polydactyly	J:311933
	right pulmonary isomerism	J:146805
	right-sided stomach	J:146805
	situs inversus	J:311933
	transposition of great arteries	J:146805, J:311933
	ventricular septal defect	J:311933
Megf8hlb611/Megf8hlb611 involves: C57BL/6J * C3H/HeJ	abnormal heart and great artery attachment	J:146957
	abnormal heart left ventricle morphology	J:146957
	abnormal liver morphology	J:146957
	abnormal stomach position or orientation	J:146957
	abnormal ureter morphology	J:146957
	absent coronary sinus	J:146957
	absent spleen	J:146957
	accessory spleen	J:146957
	anomalous pulmonary venous connection	J:146957
	atrial septal defect	J:146957
	complete atrioventricular septal defect	J:146957
	dextrocardia	J:146957
	heterotaxia	J:146957
	mesocardia	J:146957
	polydactyly	J:146957
	renal hypoplasia	J:146957
	right aortic arch	J:146957
	right atrial isomerism	J:146957
	right pulmonary isomerism	J:146957
	trabecula carnea hypoplasia	J:146957
	transposition of great arteries	J:146957
	ventricular septal defect	J:146957
Megf8m687Ddg/Megf8m687Ddg involves: C3H/He * C57BL/6	abnormal axon fasciculation	J:159834, J:206541
	abnormal nervous system morphology	J:159834
	abnormal ophthalmic nerve morphology	J:159834, J:206541
	abnormal spinal nerve morphology	J:159834
	abnormal trigeminal nerve morphology	J:206541
Megf8tm1.1Ddg/Megf8tm1.1Ddg involves: 129S6/SvEvTac * BALB/cJ	abnormal autopod morphology	J:206541
	abnormal axon extension	J:206541
	abnormal axon fasciculation	J:206541
	abnormal cardiac outflow tract development	J:206541
	abnormal direction of embryo turning	J:206541
	abnormal direction of heart looping	J:206541
	abnormal glossopharyngeal nerve morphology	J:206541
	abnormal heart atrium morphology	J:206541
	abnormal maxillary nerve morphology	J:206541
	abnormal mitral valve morphology	J:206541
	abnormal ophthalmic nerve morphology	J:206541
	abnormal spinal nerve morphology	J:206541
	abnormal thoracic cage morphology	J:206541
	abnormal tricuspid valve morphology	J:206541
	abnormal trigeminal nerve morphology	J:206541
	abnormal vagus nerve morphology	J:206541
	atrial septal defect	J:206541
	normal cardiovascular system phenotype	J:206541
	delayed bone ossification	J:206541
	delayed limb development	J:206541
	edema	J:206541
	exencephaly	J:206541
	heart right ventricle outflow tract stenosis	J:206541
	lethality throughout fetal growth and development, complete penetrance	J:206541
	preaxial polydactyly	J:206541
	split sternum	J:206541
	ventricular septal defect	J:206541
Megf8tm1.2Ddg/Megf8tm1.2Ddg H2az2Tg(Wnt1-cre)11Rth/H2az2+ involves: 129S6/SvEvTac * C57BL/6J * CBA/J	abnormal axon fasciculation	J:206541
	abnormal ophthalmic nerve morphology	J:206541
	normal limbs/digits/tail phenotype	J:206541
	normal nervous system phenotype	J:206541
Megf8tm1.2Ddg/Megf8tm1.2Ddg Mesp1tm2(cre)Ysa/Mesp1+ involves: 129S6/SvEvTac * C57BL/6NCrlj * CBA/JNCrlj	normal cardiovascular system phenotype	J:206541