48 phenotypes from 8 alleles in 12 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nlgn3em1(IMPC)Rbrc/Y C57BL/6NJcl-Nlgn3em1(IMPC)Rbrc/Rbrc	abnormal blood uric acid level	J:211773
	abnormal eosinophil cell number	J:211773
	abnormal hematocrit	J:211773
	abnormal hemoglobin content	J:211773
	abnormal locomotor activation	J:211773
	abnormal red blood cell distribution width	J:211773
	hyperactivity	J:211773
	increased bone mineral density	J:211773
Nlgn3em1(IMPC)Rbrc/Nlgn3em1(IMPC)Rbrc C57BL/6NJcl-Nlgn3em1(IMPC)Rbrc/Rbrc	abnormal neutrophil cell number	J:211773
	decreased anxiety-related response	J:211773
	hyperactivity	J:211773
Nlgn3tm1.1Htz/Y involves: C57BL/6 * FVB/N	abnormal motor coordination/balance	J:167116
	abnormal righting response	J:167116
	abnormal spatial learning	J:167116
	decreased startle reflex	J:167116
	decreased vertical activity	J:167116
	decreased vocalization	J:167116
	enhanced coordination	J:167116
	impaired coordination	J:167116
	increased growth rate	J:167116
	increased thigmotaxis	J:167116
	normal nervous system phenotype	J:167116
Nlgn3tm1.1Htz/Nlgn3tm1.1Htz involves: C57BL/6 * FVB/N	abnormal learning/memory/conditioning	J:167116
	abnormal righting response	J:167116
	abnormal spatial learning	J:167116
	increased thigmotaxis	J:167116
	postnatal growth retardation	J:167116
Nlgn3tm1Bros/Nlgn3tm1Bros B6.Cg-Nlgn3tm1Bros	abnormal social investigation	J:151116
	normal behavior/neurological phenotype	J:151116
	decreased brain size	J:151116
	decreased vocalization	J:151116
	impaired contextual conditioning behavior	J:151116
	impaired cued conditioning behavior	J:151116
	impaired olfaction	J:151116
	increased exploration in new environment	J:151116
	increased locomotor activity	J:151116
	normal nervous system phenotype	J:151116
Nlgn3tm1Rhn/Y involves: 129S6/SvEvTac * C57BL/6	abnormal miniature excitatory postsynaptic currents	J:187744
	abnormal motor coordination/balance	J:187744
	absent long-term depression	J:187744
	impaired synaptic plasticity	J:187744
	increased CNS synapse formation	J:187744
	increased excitatory postsynaptic current amplitude	J:187744
Nlgn3tm1Rhn/Y Tg(Pcp2-tTA)3Horr/0 involves: 129S6/SvEvTac * C57BL/6 * FVB/N	normal nervous system phenotype	J:187744
Nlgn3tm1Sud/Y involves: 129S1/Sv * 129X1/SvJ	enhanced learning	J:214636
	increased locomotor activity	J:214636
	increased stereotypic behavior	J:214636
Nlgn3tm1Sud/Y involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal inhibitory postsynaptic currents	J:125344
	abnormal social investigation	J:125344
	abnormal spatial learning	J:125344
Nlgn3tm1Sud/Y Tg(Drd1-cre)EY262Gsat/0 involves: 129S1/Sv * 129X1/SvJ * FVB/N	enhanced learning	J:214636
	increased stereotypic behavior	J:214636
Nlgn3tm1Sud/Y Tg(Drd1-tdTomato)5Calak/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	decreased miniature inhibitory postsynaptic current frequency	J:214636
Nlgn3tm2.1Sud/Y involves: 129S1/Sv * 129X1/SvJ	enhanced learning	J:214636
	increased locomotor activity	J:214636
	increased stereotypic behavior	J:214636
	increased vertical activity	J:214636
	stereotypic behavior	J:214636
Nlgn3tm2.1Sud/Y involves: 129S1/Sv * 129X1/SvJ * C57BL/6	no abnormal phenotype detected	J:125344
Nlgn3tm2.1Sud/Y Tg(Drd1-tdTomato)5Calak/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	decreased miniature inhibitory postsynaptic current frequency	J:214636
Nlgn3tm3.1Sud/Nlgn3tm3.1Sud involves: 129S1/Sv * 129X1/SvJ	abnormal excitatory postsynaptic potential	J:184114
	abnormal glutamate-mediated receptor currents	J:184114
	abnormal miniature excitatory postsynaptic currents	J:184114
	normal nervous system phenotype	J:184114
	reduced AMPA-mediated synaptic currents	J:184114
Nlgn3tm4.1Sud/Y involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	enhanced learning	J:214636
	hyperactivity	J:214636
Nlgn3tm4.1Sud/Y Pvalbtm1(cre)Arbr/Pvalb+ involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	decreased locomotor activity	J:214636
Nlgn3tm4.1Sud/Y Tg(Adora2a-cre)2MDkde/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	normal behavior/neurological phenotype	J:214636
Nlgn3tm4.1Sud/Y Tg(Drd1-cre)EY262Gsat/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N * SJL	enhanced learning	J:214636
	hyperactivity	J:214636
Nlgn3tm4.1Sud/Y Tg(Nes-cre)1Kln/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	increased locomotor activity	J:214636
Nlgn3tm4.1Sud/Y Tg(Pcp2-cre)2Mpin/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	increased locomotor activity	J:214636
Nlgn3tm4.1Sud/Y Tg(Pcp2-cre)2Mpin/? involves: 129S1/Sv * 129X1/SvJ * C57BL/6NTac	decreased excitatory postsynaptic current amplitude	J:227671
	normal nervous system phenotype	J:227671