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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Afg3l2
AFG3-like AAA ATPase 2
MGI:1916847
22 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Afg3l1tm1.1Arte/Afg3l1tm1.1Arte
Afg3l2tm1Arte/Afg3l2tm1Arte
Gt(ROSA)26Sortm1Lrsn/Gt(ROSA)26Sor+
Tg(Plp1-cre/ERT)3Pop/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * C57BL/6N
abnormal dermal layer morphology J:237410
abnormal melanoblast morphology J:237410
abnormal mitochondrial physiology J:237410
abnormal oligodendrocyte morphology J:237410
abnormal oligodendrocyte physiology J:237410
abnormal Schwann cell morphology J:237410
abnormal sciatic nerve morphology J:237410
decreased melanocyte number J:237410
demyelination J:237410
dilated mitochondria J:237410
Afg3l1tm1.1Arte/Afg3l1tm1.1Arte
Afg3l2tm1Arte/Afg3l2tm1Arte
Tg(Plp1-cre/ERT)3Pop/0
involves: C57BL/6J * C57BL/6N
abnormal brain white matter morphology J:237410
abnormal coat/hair pigmentation J:237410
abnormal spinal cord white matter morphology J:237410
astrocytosis J:237410
axon degeneration J:237410
decreased body fat mass J:237410
decreased body weight J:237410
demyelination J:237410
impaired coordination J:237410
microgliosis J:237410
Afg3l2tm1Arte/Afg3l2tm1Arte
Gt(ROSA)26Sortm1Lrsn/Gt(ROSA)26Sor+
Tg(Pcp2-cre)2Mpin/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal nervous system electrophysiology J:193564
abnormal Purkinje cell morphology J:193564
Afg3l2tm1Arte/Afg3l2tm1Arte
Gt(ROSA)26Sortm1Lrsn/Gt(ROSA)26Sor+
Tg(Plp1-cre/ERT)3Pop/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
abnormal mitochondrial shape J:237410
dilated mitochondria J:237410

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/13/2018
MGI 6.11
The Jackson Laboratory