56 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Wdr45em1(IMPC)J/Y C57BL/6NJ-Wdr45em1(IMPC)J/J	abnormal auditory brainstem response	J:211773
	abnormal bone structure	J:211773
	abnormal startle reflex	J:211773
	hyperactivity	J:211773
	increased circulating HDL cholesterol level	J:211773
Wdr45em1(IMPC)J/Wdr45em1(IMPC)J C57BL/6NJ-Wdr45em1(IMPC)J/J	decreased bone mineral content	J:211773
	decreased bone mineral density	J:211773
	increased circulating alkaline phosphatase level	J:211773
Wdr45em1Wrst/Y involves: C57BL/6N * FVB	abnormal cerebellar Purkinje cell layer	J:307284
	abnormal mitochondrial ATP synthesis coupled electron transport	J:307284
	abnormal social recognition	J:307284
	anisocytosis	J:307284
	astrocytosis	J:307284
	decreased circulating amylase level	J:307284
	decreased circulating lactate level	J:307284
	decreased circulating serum albumin level	J:307284
	decreased circulating total protein level	J:307284
	decreased circulating triglyceride level	J:307284
	decreased circulating unsaturated transferrin level	J:307284
	decreased cornea thickness	J:307284
	decreased dopaminergic neuron number	J:307284
	homeostasis/metabolism phenotype	J:307284
	normal homeostasis/metabolism phenotype	J:307284
	impaired coordination	J:307284
	impaired hearing	J:307284
	increased alkaline phosphatase activity	J:307284
	increased body weight	J:307284
	increased circulating aspartate transaminase level	J:307284
	increased circulating glucose level	J:307284
	increased circulating iron level	J:307284
	increased circulating lactate dehydrogenase level	J:307284
	increased erythrocyte cell number	J:307284
	increased eye anterior chamber depth	J:307284
	increased hemoglobin content	J:307284
	increased leukocyte cell number	J:307284
	increased locomotor activity	J:307284
	increased or absent threshold for auditory brainstem response	J:307284
	limb grasping	J:307284
	lipofuscinosis	J:307284
	neurodegeneration	J:307284
	retina degeneration	J:307284
	tremors	J:307284
Wdr45em1Wrst/Wdr45+ involves: C57BL/6N * FVB	impaired coordination	J:307284
	increased locomotor activity	J:307284
	increased or absent threshold for auditory brainstem response	J:307284
Wdr45em1Wrst/Wdr45em1Wrst involves: C57BL/6N * FVB	abnormal cerebellar Purkinje cell layer	J:307284
	abnormal mitochondrial ATP synthesis coupled electron transport	J:307284
	anisocytosis	J:307284
	astrocytosis	J:307284
	decreased circulating lactate level	J:307284
	decreased cornea thickness	J:307284
	decreased dopaminergic neuron number	J:307284
	decreased total retina thickness	J:307284
	hematopoietic system phenotype	J:307284
	normal homeostasis/metabolism phenotype	J:307284
	impaired coordination	J:307284
	impaired glucose tolerance	J:307284
	impaired hearing	J:307284
	increased alkaline phosphatase activity	J:307284
	increased body weight	J:307284
	increased circulating aspartate transaminase level	J:307284
	increased circulating glucose level	J:307284
	increased circulating iron level	J:307284
	increased circulating lactate dehydrogenase level	J:307284
	increased eye anterior chamber depth	J:307284
	increased locomotor activity	J:307284
	increased or absent threshold for auditory brainstem response	J:307284
	limb grasping	J:307284
	lipofuscinosis	J:307284
	neurodegeneration	J:307284
	retina degeneration	J:307284
	tremors	J:307284
Wdr45tm1Beij/Wdr45+ Tg(Nes-cre)1Kln/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6N * SJL	axonal spheroids	J:281235
	impaired autophagy	J:281235
Wdr45tm1Beij/Y Tg(Nes-cre)1Kln/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6N * SJL	abnormal excitatory postsynaptic potential	J:281235
	abnormal spatial working memory	J:281235
	astrocytosis	J:281235
	axon degeneration	J:281235
	axonal spheroids	J:281235
	normal behavior/neurological phenotype	J:281235
	brain vacuoles	J:281235
	demyelination	J:281235
	impaired autophagy	J:281235
	impaired contextual conditioning behavior	J:281235
	impaired coordination	J:281235
	impaired spatial learning	J:281235
	reduced long-term potentiation	J:281235
Wdr45tm1Beij/Wdr45tm1Beij Tg(Nes-cre)1Kln/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6N * SJL	axonal spheroids	J:281235
	impaired autophagy	J:281235