Wdr45^tm1Beij
Targeted Allele Detail

Summary

• Symbol: Wdr45^tm1Beij
• Name: WD repeat domain 45; targeted mutation 1, Chinese Academy of Sciences
• MGI ID: MGI:6385188
• Synonyms: Wdr45^fl
• Gene: Wdr45 Location: ChrX:7588193-7594440 bp, + strand Genetic Position: ChrX, 3.48 cM
• Alliance: Wdr45^tm1Beij page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:281235
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exons 8 through 14 were floxed. (J:281235)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wdr45 Mutation: 20 strains or lines available

References

• Original: J:281235 Zhao YG, et al., The autophagy gene Wdr45/Wipi4 regulates learning and memory function and axonal homeostasis. Autophagy. 2015;11(6):881-90
• All: 1 reference(s)