67 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ldlrtm1Her/Ldlrtm1Her Nr1h3tm1.1Djm/Nr1h3tm1.1Djm Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 * DBA	abnormal cholesterol homeostasis	J:184536
	decreased circulating cholesterol level	J:184536
	decreased circulating triglyceride level	J:184536
	decreased physiological sensitivity to xenobiotic	J:184536
	increased liver cholesterol level	J:184536
	increased susceptibility to atherosclerosis	J:184536
Nr1h2tm1.1Gstr/Nr1h2tm1.1Gstr Nr1h3tm1.1Gstr/Nr1h3tm1.1Gstr involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal alveolar lamellar body morphology	J:234268
	abnormal astrocyte morphology	J:81790
	abnormal brain ependyma morphology	J:81790
	abnormal brain vasculature morphology	J:81790
	abnormal brain ventricle morphology	J:81790
	abnormal cerebral aqueduct morphology	J:81790
	abnormal cholesterol homeostasis	J:81790
	abnormal choroid plexus morphology	J:81790
	abnormal lateral ventricle morphology	J:81790
	abnormal lipid homeostasis	J:81790
	abnormal lipid level	J:234268
	abnormal lung morphology	J:234268
	abnormal myelin sheath morphology	J:81790
	abnormal myelination	J:81790
	abnormal neurohypophysis median eminence morphology	J:81790
	abnormal pulmonary alveolar parenchyma morphology	J:234268
	abnormal pulmonary alveolar system morphology	J:234268
	abnormal spinal cord central canal morphology	J:81790
	abnormal substantia nigra pars reticulata morphology	J:81790
	abnormal third ventricle morphology	J:81790
	absent choroid plexus	J:81790
	astrocytosis	J:81790
	decreased neuron number	J:81790
	increased lung squamous cell carcinoma incidence	J:234268
	increased macrophage derived foam cell number	J:81790, J:234268
	intracranial hemorrhage	J:81790
	lung inflammation	J:234268
	neuron degeneration	J:81790
	premature death	J:234268
	respiratory distress	J:234268
	small fourth ventricle	J:81790
	small lateral ventricles	J:81790
	small third ventricle	J:81790
Nr1h2tm1Djm/Nr1h2tm1Djm Nr1h3tm1Djm/Nr1h3tm1Djm involves: 129S6/SvEvTac	increased liver cholesterol level	J:64343
Nr1h2tm1Djm/Nr1h2tm1Djm Nr1h3tm1Djm/Nr1h3tm1Djm involves: 129S6/SvEvTac * C57BL/6	abnormal bone marrow cell physiology	J:125452
	abnormal female reproductive system morphology	J:120923
	abnormal female reproductive system physiology	J:120923
	abnormal macrophage morphology	J:125452
	abnormal male reproductive system morphology	J:120923
	abnormal male reproductive system physiology	J:120923
	abnormal myometrium morphology	J:120923
	abnormal parturition	J:120923
	abnormal seminiferous tubule morphology	J:120913
	abnormal Sertoli cell morphology	J:120913
	abnormal spermatogonia proliferation	J:120913
	abnormal uterus physiology	J:120923
	decreased circulating luteinizing hormone level	J:120913
	decreased circulating testosterone level	J:120913
	decreased testis weight	J:120913
	hindlimb paralysis	J:120923
	impaired smooth muscle contractility	J:120923
	increased male germ cell apoptosis	J:120913
	increased susceptibility to bacterial infection	J:81696
	increased susceptibility to induced morbidity/mortality	J:81696
	Leydig cell hypertrophy	J:120913
	pregnancy-related premature death	J:120923
	reduced male fertility	J:120913
	seminiferous tubule degeneration	J:120913
	testicular atrophy	J:120913
Nr1h3tm1Djm/Nr1h3tm1Djm Nus1tm1.1Qrm/Nus1tm1.1Qrm Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ involves: 129 * C57BL/6 * DBA * SJL	normal homeostasis/metabolism phenotype	J:243753
	increased liver cholesterol level	J:243753
Nr1h3tm1Djm/Nr1h3tm1Djm Tg(APPswe,PSEN1dE9)85Dbo/0 involves: 129S6/SvEvTac * C3H * C57BL/6	amyloid beta deposits	J:122372
Tg(Fabp1-Nr1h3)#Wexi/? Tg(Fabp1-NR1I2)#Wexi/? involves: 129X1/SvJ * C57BL/6	enlarged liver	J:135594
	increased liver triglyceride level	J:135594