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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ikbkg
inhibitor of kappaB kinase gamma
MGI:1338074
35 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Casp8tm1Clie/Casp8tm1Clie
Ikbkgtm1.1Chtr/Ikbkgtm1.1Chtr
Tg(Alb1-cre)7Gsc/0
involves: 129P2/OlaHsd * C57BL/6 * FVB/N 		abnormal biliary tract morphology J:218665
abnormal circulating enzyme level J:218665
abnormal liver morphology J:218665
decreased body size J:218665
enlarged liver J:218665
hepatic necrosis J:218665
increased bile salt level J:218665
increased circulating alkaline phosphatase level J:218665
increased circulating bilirubin level J:218665
intrahepatic cholestasis J:218665
liver fibrosis J:218665
normal neoplasm J:218665
Cyldtm1.1Mpa/Cyldtm1.1Mpa
Ikbkgtm1.1Mpa/Ikbkgtm1.1Mpa
Tg(Vil1-cre)997Gum/0
B6.Cg-Cyldtm1.1Mpa Ikbkgtm1.1Mpa Tg(Vil1-cre)997Gum 		colitis J:175865
crypts of Lieberkuhn abscesses J:175865
Cyldtm1.1Mpa/Cyldtm1.1Mpa
Ikbkgtm1.1Mpa/Y
Tg(Vil1-cre)997Gum/0
B6.Cg-Cyldtm1.1Mpa Ikbkgtm1.1Mpa Tg(Vil1-cre)997Gum 		colitis J:175865
crypts of Lieberkuhn abscesses J:175865
Faddtm1Mpa/Faddtm1Mpa
Ikbkgtm1.1Mpa/Ikbkgtm1.1Mpa
Tg(Alb1-cre)7Gsc/0
involves: C57BL/6 * FVB/N 		abnormal enzyme/coenzyme activity J:118336
decreased apoptosis J:118336
decreased circulating alanine transaminase level J:118336
liver inflammation J:118336
normal liver/biliary system phenotype J:118336
Ikbkgtm1.1Chtr/Ikbkgtm1.1Chtr
Map3k7tm1Aki/Map3k7tm1Aki
Tg(Alb1-cre)7Gsc/0
involves: 129P2/OlaHsd * FVB/N 		normal homeostasis/metabolism phenotype J:160521
increased circulating alanine transaminase level J:160521
increased circulating aspartate transaminase level J:160521
increased hepatocyte apoptosis J:160521
increased hepatocyte proliferation J:160521
normal liver/biliary system phenotype J:160521
normal mortality/aging J:160521
Ikbkgtm1.1Dwat/Ikbkgtm1.1Dwat
Tnfrsf1atm1Imx/Tnfrsf1atm1Imx
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac 		premature death J:202106
Ikbkgtm1.1Dwat/Y
Tnfrsf1atm1Imx/Tnfrsf1atm1Imx
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac 		abnormal hepatocyte morphology J:202106
abnormal liver physiology J:202106
abnormal liver regeneration J:202106
hepatic steatosis J:202106
normal immune system phenotype J:202106
increased circulating alanine transaminase level J:202106
increased circulating aspartate transaminase level J:202106
increased circulating bilirubin level J:202106
increased circulating lactate dehydrogenase level J:202106
liver fibrosis J:202106
liver inflammation J:202106
macrovesicular hepatic steatosis J:202106
microvesicular hepatic steatosis J:202106
premature death J:202106
preweaning lethality, incomplete penetrance J:202106
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory