Lpcat3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lpcat3
lysophosphatidylcholine acyltransferase 3
MGI:1315211

18 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lpcat3^{tm1a(EUCOMM)Wtsi}/Lpcat3^{tm1a(EUCOMM)Wtsi} involves: C57BL/6N	abnormal lipid metabolism	J:220827
	decreased circulating glucose level	J:220827
	postnatal lethality, complete penetrance	J:220827
Lpcat3^{tm1c(EUCOMM)Wtsi}/Lpcat3^{tm1c(EUCOMM)Wtsi} involves: C57BL/6 * C57BL/6N * SJL	abnormal liver physiology	J:220827
	decreased circulating triglyceride level	J:220827
Lpcat3^{tm1c(EUCOMM)Wtsi}/Lpcat3^{tm1c(EUCOMM)Wtsi} Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ involves: C57BL/6 * C57BL/6N * SJL	abnormal circulating apolipoprotein level	J:220827
	abnormal lipid homeostasis	J:220827
	abnormal lipid level	J:220827
	abnormal phospholipid level	J:220827
	decreased circulating triglyceride level	J:220827
	decreased circulating VLDL phospholipid level	J:220827
	decreased circulating VLDL triglyceride level	J:220827
	hepatic steatosis	J:220827
	increased liver cholesterol level	J:220827
	increased liver triglyceride level	J:220827
Lpcat3^{tm1c(EUCOMM)Wtsi}/Lpcat3^{tm1c(EUCOMM)Wtsi} Tg(Vil1-cre)997Gum/0 involves: C57BL/6 * C57BL/6N * SJL	abnormal enterocyte morphology	J:220827
	abnormal lipid level	J:220827
	decreased body weight	J:220827
	decreased circulating glucose level	J:220827
	decreased circulating insulin level	J:220827
	decreased circulating triglyceride level	J:220827
	postnatal growth retardation	J:220827

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23