47 phenotypes from 9 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Alpltm1(cre)Nagy/Alpl+ Dnmt3btm5.1Enl/Dnmt3btm5.2Enl involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * FVB/N	normal reproductive system phenotype	J:91108
Dnmt3bem1(IMPC)Mbp/Dnmt3b+ C57BL/6N-Dnmt3bem1(IMPC)Mbp/Ucd	hemorrhage	J:211773
Dnmt3bem1(IMPC)Mbp/Dnmt3bem1(IMPC)Mbp C57BL/6N-Dnmt3bem1(IMPC)Mbp/Ucd	abnormal craniofacial morphology	J:211773
	abnormal facial morphology	J:211773
	abnormal placenta morphology	J:211773
	abnormal placenta vasculature	J:211773
	cleft palate	J:211773
	edema	J:211773
	embryonic growth retardation	J:211773
	hemorrhage	J:211773
	microphthalmia	J:211773
	preweaning lethality, complete penetrance	J:211773
Dnmt3bMommeD14/Dnmt3bMommeD14 Tg(HBA1-GFP)1Ew/0 involves: FVB/N	abnormal epigenetic regulation of gene expression	J:198944
	preweaning lethality, incomplete penetrance	J:198944
Dnmt3bMommeD14/Dnmt3btm1Enl Tg(HBA1-GFP)1Ew/0 involves: FVB/N	abnormal epigenetic regulation of gene expression	J:198944
	abnormal head morphology	J:198944
	decreased body height	J:198944
Dnmt3btm1.1Ics/Dnmt3btm2.1Ics involves: 129S2/SvPas * C57BL/6J	abnormal cranium morphology	J:160567
	abnormal DNA methylation	J:160567
	abnormal skeleton morphology	J:160567
	decreased body size	J:160567
	enlarged frontal bone	J:160567
	enlarged interparietal bone	J:160567
	lumbar vertebral transformation	J:160567
	postnatal lethality, incomplete penetrance	J:160567
	short snout	J:160567
	thoracic vertebral transformation	J:160567
Dnmt3btm1Enl/Dnmt3btm1Enl involves: 129S4/SvJae * C57BL/6	abnormal interventricular septum morphology	J:106540
	embryonic growth retardation	J:58298
	embryonic lethality during organogenesis, incomplete penetrance	J:106540
	hemorrhage	J:106540
	incomplete rostral neuropore closure	J:58298
	lethality throughout fetal growth and development, complete penetrance	J:106540
	prenatal lethality, complete penetrance	J:58298
	small liver	J:106540
Dnmt3btm1Enl/Dnmt3btm6Enl involves: 129S4/SvJae * C57BL/6	decreased birth weight	J:106540
	decreased thymocyte number	J:106540
	increased thymocyte apoptosis	J:106540
	neonatal lethality, incomplete penetrance	J:106540
	small thymus	J:106540
Dnmt3btm1Enl/Dnmt3btm7Enl involves: 129S4/SvJae * C57BL/6	decreased birth weight	J:106540
	decreased double-positive T cell number	J:106540
	decreased thymocyte number	J:106540
	increased double-negative T cell number	J:106540
	increased thymocyte apoptosis	J:106540
	neonatal lethality, complete penetrance	J:106540
	small thymus	J:106540
Dnmt3btm5.2Enl/Dnmt3btm5.2Enl involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * FVB/N	decreased embryo size	J:91108
	open neural tube	J:91108
	prenatal lethality, complete penetrance	J:91108
Dnmt3btm6Enl/Dnmt3btm6Enl involves: 129S4/SvJae * C57BL/6	decreased birth weight	J:106540
	decreased thymocyte number	J:106540
	increased thymocyte apoptosis	J:106540
	large anterior fontanelle	J:106540
	neonatal lethality, incomplete penetrance	J:106540
	ocular hypertelorism	J:106540
	short nasal bone	J:106540
	small thymus	J:106540
	wide frontal bone	J:106540
Dnmt3btm6Enl/Dnmt3btm7Enl involves: 129S4/SvJae * C57BL/6	abnormal nasal bone morphology	J:106540
	decreased birth weight	J:106540
	decreased thymocyte number	J:106540
	increased thymocyte apoptosis	J:106540
	neonatal lethality, incomplete penetrance	J:106540
	postnatal lethality, complete penetrance	J:106540
Dnmt3btm7Enl/Dnmt3btm7Enl involves: 129S4/SvJae * C57BL/6	decreased thymocyte number	J:106540
	increased thymocyte apoptosis	J:106540
	neonatal lethality, incomplete penetrance	J:106540
	postnatal lethality, complete penetrance	J:106540
	small thymus	J:106540