56 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Itchtm1(NCOM)Cmhd/Itch+ C57BL/6N-Itchtm1(NCOM)Cmhd/Tcp	increased mean corpuscular volume	J:165965
Itchtm1.1Alta/Itchtm1.1Alta Foxp3tm4(YFP/icre)Ayr/Foxp3+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal immunoglobulin level	J:204685
	abnormal interleukin secretion	J:204685
	abnormal lymph organ size	J:204685
	abnormal lymphopoiesis	J:204685
	abnormal regulatory T cell physiology	J:204685
	abnormal T-helper 2 cell differentiation	J:204685
	abnormal T-helper 2 physiology	J:204685
	decreased CD4-positive, alpha-beta T cell number	J:204685
	dermatitis	J:204685
	enlarged lymph nodes	J:204685
	enlarged spleen	J:204685
	normal immune system phenotype	J:204685
	increased CD4-positive, alpha-beta T cell number	J:204685
	increased CD8-positive, alpha-beta T cell number	J:204685
	increased eosinophil cell number	J:204685
	increased IgA level	J:204685
	increased IgE level	J:204685
	increased IgG1 level	J:204685
	increased inflammatory response	J:204685
	increased interleukin-4 secretion	J:204685
	increased interleukin-5 secretion	J:204685
	increased interleukin-10 secretion	J:204685
	increased interleukin-13 secretion	J:204685
	increased interleukin-17 secretion	J:204685
	increased leukocyte cell number	J:204685
	increased regulatory T cell apoptosis	J:204685
	increased regulatory T cell number	J:204685
	lung inflammation	J:204685
	premature death	J:204685
	skin lesions	J:204685
	weight loss	J:204685
Itchtm1b(EUCOMM)Hmgu/Itchtm1b(EUCOMM)Hmgu C57BL/6N-Itchtm1b(EUCOMM)Hmgu/H	abnormal bone structure	J:211773
	abnormal esophagus morphology	J:211773
	abnormal head size	J:211773
	abnormal startle reflex	J:211773
	abnormal tooth morphology	J:211773
	decreased bone mineral content	J:211773
	decreased bone mineral density	J:211773
	decreased circulating alkaline phosphatase level	J:211773
	decreased circulating fructosamine level	J:211773
	decreased exploration in new environment	J:211773
	decreased fasting circulating glucose level	J:211773
	decreased total body fat amount	J:211773
	enlarged gallbladder	J:211773
	enlarged kidney	J:211773
	enlarged spleen	J:211773
	increased blood urea nitrogen level	J:211773
	increased circulating amylase level	J:211773
	increased circulating aspartate transaminase level	J:211773
	increased circulating calcium level	J:211773
	increased circulating phosphate level	J:211773
	increased circulating total protein level	J:211773
	increased heart weight	J:211773
	increased lean body mass	J:211773
	increased spleen weight	J:211773
	tremors	J:211773