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Mammalian Phenotype Ontology Annotations
Query Results - Summary
potassium inwardly-rectifying channel, subfamily J, member 10
74 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
preweaning lethality, complete penetrance J:211773
involves: 129S6/SvEvTac * C3H * C57BL/6 * C57BL/6J * SJL
abnormal astrocyte morphology J:126082
abnormal astrocyte physiology J:126082
abnormal CNS glial cell morphology J:126082
abnormal CNS synaptic transmission J:126082
abnormal excitatory postsynaptic currents J:126082
abnormal eye physiology J:126082
abnormal motor capabilities/coordination/movement J:126082
abnormal nervous system morphology J:126082
abnormal nervous system physiology J:126082
abnormal oligodendrocyte morphology J:126082
abnormal spinal cord white matter morphology J:126082
ataxia J:126082
brain vacuoles J:126082
decreased body size J:126082
decreased brain size J:126082
delayed eyelid opening J:126082
dilated lateral ventricles J:126082
enhanced long term potentiation J:126082
eyelids fail to open J:126082
gliosis J:126082
hindlimb paralysis J:126082
impaired righting response J:126082
increased post-tetanic potentiation J:126082
lethargy J:126082
premature death J:126082
slow postnatal weight gain J:126082
thin cerebral cortex J:126082
tonic-clonic seizures J:126082
tremors J:126082
involves: 129S1/Sv * C57BL/6J
abnormal eye physiology J:63635
involves: 129S1/Sv
abnormal renal tubule morphology J:226598
decreased urine calcium level J:226598
decreased urine creatinine level J:226598
increased urine sodium level J:226598
polyuria J:226598
postnatal growth retardation J:226598
postnatal lethality, complete penetrance J:226598
involves: 129S1/Sv * C57BL/6J
abnormal cochlea morphology J:108878
abnormal cochlear endolymph ionic homeostasis J:75599
abnormal cochlear nerve morphology J:108878
abnormal crista ampullaris neuroepithelium morphology J:108878
abnormal eye electrophysiology J:63635
abnormal motor capabilities/coordination/movement J:77663
abnormal motor coordination/balance J:63635, J:77663
abnormal myelination J:77663
abnormal nervous system electrophysiology J:77663
abnormal oligodendrocyte morphology J:77663
abnormal posture J:77663
abnormal Reissner membrane morphology J:75599, J:108878
abnormal scala media morphology J:108878
abnormal spinal cord morphology J:77663
abnormal spinal cord white matter morphology J:77663
abnormal stria vascularis morphology J:108878
abnormal tectorial membrane morphology J:108878
absent endocochlear potential J:75599
absent pinna reflex J:75599
absent startle reflex J:108878
axon degeneration J:77663
cochlear ganglion degeneration J:108878
cochlear inner hair cell degeneration J:108878
cochlear outer hair cell degeneration J:108878
collapsed Reissner membrane J:108878
decreased body size J:63635, J:77663
decreased body weight J:77663
dehydration J:77663
distended Reissner membrane J:108878
normal hearing/vestibular/ear phenotype J:75599
hindlimb paralysis J:77663
impaired balance J:63635
impaired hearing J:75599
impaired righting response J:108878
increased or absent threshold for auditory brainstem response J:75599
jerky movement J:63635
organ of Corti degeneration J:108878
postnatal growth retardation J:63635, J:77663, J:108878
postnatal lethality, complete penetrance J:63635, J:77663, J:108878
tremors J:77663
utricular macular degeneration J:108878
vestibular ganglion degeneration J:108878
vestibular hair cell degeneration J:108878
vestibular saccular macula degeneration J:108878
normal vision/eye phenotype J:63635
weakness J:77663

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.13
The Jackson Laboratory