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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Etv6
ets variant 6
MGI:109336
61 phenotypes from 6 alleles in 9 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Etv6em1(IMPC)Rbrc/Etv6+
C57BL/6NJcl-Etv6em1(IMPC)Rbrc/Rbrc
abnormal heart morphology J:211773
abnormal heart shape J:211773
abnormal heart weight J:211773
abnormal liver morphology J:211773
decreased bone mineral density J:211773
decreased circulating calcium level J:211773
decreased circulating cholesterol level J:211773
decreased circulating HDL cholesterol level J:211773
decreased circulating serum albumin level J:211773
decreased circulating total protein level J:211773
decreased erythrocyte cell number J:211773
enlarged heart J:211773
increased blood uric acid level J:211773
increased heart atrium size J:211773
increased kidney weight J:211773
increased large unstained cell number J:211773
increased spleen weight J:211773
small liver J:211773
thrombocytopenia J:211773
Etv6em1(IMPC)Rbrc/Etv6em1(IMPC)Rbrc
C57BL/6NJcl-Etv6em1(IMPC)Rbrc/Rbrc
preweaning lethality, complete penetrance J:211773
Etv6em3Knic/Etv6+
involves: C57BL/6J
abnormal B cell number J:342774
abnormal common myeloid progenitor cell morphology J:342774
abnormal hematopoietic precursor cell morphology J:342774
abnormal hemopoiesis J:342774
abnormal platelet shape J:342774
normal hematopoietic system phenotype J:342774
impaired blood coagulation J:342774
Etv6tm1(RUNX1)Haho/Etv6+
Tg(Mx1-cre)1Cgn/0
involves: 129S1/Sv * C57BL/6 * CBA
abnormal bone marrow cell physiology J:151639
abnormal common lymphocyte progenitor cell morphology J:151639
abnormal common myeloid progenitor cell morphology J:151639
abnormal definitive hematopoiesis J:151639
abnormal lymphopoiesis J:151639
decreased B cell number J:151639
decreased erythroid progenitor cell number J:151639
decreased lymphocyte cell number J:151639
decreased neutrophil cell number J:151639
normal immune system phenotype J:151639
increased hematopoietic stem cell number J:151639
increased incidence of tumors by chemical induction J:151639
increased leukemia incidence J:151639
myeloid hyperplasia J:151639
thrombocytopenia J:151639
Etv6tm1(RUNX1)Haho/Etv6+
Tg(Gata1-cre)1Sho/0
involves: 129S1/Sv * C57BL/6 * CD-1 * Swiss Webster
abnormal B cell differentiation J:151639
normal embryo phenotype J:151639
embryonic lethality during organogenesis, incomplete penetrance J:151639
normal immune system phenotype J:151639
intestinal edema J:151639
normal neoplasm J:151639
postnatal growth retardation J:151639
postnatal lethality J:151639
Etv6tm1(RUNX1)Haho/Etv6+
Tg(CD2-icre)4Kio/0
involves: 129S1/Sv * C57BL/6 * C57BL/10 * CBA/Ca
normal immune system phenotype J:151639
Etv6tm1(RUNX1)Haho/Etv6+
Tg(VAV1-cre)1Graf/0
involves: 129S1/Sv * C57BL/6
abnormal myeloblast morphology/development J:151639
arrested B cell differentiation J:151639
decreased B cell number J:151639
decreased pre-B cell number J:151639
decreased pro-B cell number J:151639
increased hematopoietic stem cell number J:151639
Etv6tm1(RUNX1)Haho/Etv6tm1(RUNX1)Haho
B6.129S1-Etv6tm1(Runx1)Haho
prenatal lethality, complete penetrance J:151639
Etv6tm1Sho/Etv6tm1Sho
involves: 129S4/SvJae * C57BL/6
abnormal visceral yolk sac morphology J:42409
absent vitelline blood vessels J:42409
normal cardiovascular system phenotype J:42409
normal embryo phenotype J:42409
embryonic growth retardation J:42409
embryonic lethality during organogenesis, complete penetrance J:42409
enlarged pericardium J:42409
Etv6tm2.1Sho/Etv6tm2.1Sho
involves: 129S1/Sv
abnormal erythropoiesis J:93052
absent vitelline blood vessels J:93052
embryonic lethality during organogenesis, incomplete penetrance J:93052
prenatal lethality, complete penetrance J:93052
Etv6tm2Sho/Etv6tm2Sho
involves: 129S1/Sv
no abnormal phenotype detected J:93052
Etv6tm2Sho/Etv6tm2Sho
Tg(Gata1-cre)1Sho/?
involves: 129S1/Sv
abnormal megakaryocyte differentiation J:93052
thrombocytopenia J:93052
Etv6tm2Sho/Etv6tm2Sho
Tg(Mx1-cre)1Cgn/?
involves: 129S1/Sv * C57BL/6 * CBA
decreased neutrophil cell number J:93052
thrombocytopenia J:93052

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory