Sfrp2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sfrp2
secreted frizzled-related protein 2
MGI:108078

23 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Dkk1^tm1Sia/Dkk1^tm1Sia Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp2^tm1Aksh/Sfrp2⁺ involves: 129 * C57BL/6 * CBA	incomplete somite formation	J:135313
Dkk1^tm1Sia/Dkk1^tm1Sia Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp2^tm1Aksh/Sfrp2^tm1Aksh involves: 129 * C57BL/6 * CBA	abnormal presomitic mesoderm morphology	J:135313
	incomplete embryo turning	J:135313
	incomplete somite formation	J:135313
Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp2^tm1Aksh/Sfrp2⁺ Sfrp5^tm1Aksh/Sfrp5^tm1Aksh Vangl2^Lp/Vangl2⁺ involves: 129 * A * C57BL/6 * LPT/LeJ	spina bifida	J:135313
Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp2^tm1Aksh/Sfrp2^tm1Aksh involves: 129 * C57BL/6	abnormal craniofacial morphology	J:106551
	abnormal rostral-caudal axis patterning	J:106551, J:135313
	abnormal rostral-caudal body axis extension	J:106551
	abnormal somite development	J:106551
	decreased somite size	J:106551
	decreased thoracic vertebrae number	J:106551
	edema	J:106551
	incomplete somite formation	J:106551, J:135313
	lethality throughout fetal growth and development, complete penetrance	J:106551
	short limbs	J:106551
	syndactyly	J:106551
Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp2^tm1Aksh/Sfrp2^tm1Aksh Sfrp5^tm1Aksh/Sfrp5⁺ involves: 129 * C57BL/6	abnormal rostral-caudal axis patterning	J:135313
	abnormal somite development	J:135313
Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp2^tm1Aksh/Sfrp2^tm1Aksh Sfrp5^tm1Aksh/Sfrp5⁺ Vangl2^Lp/Vangl2⁺ involves: 129 * A * C57BL/6 * LPT/LeJ	abnormal rostral-caudal body axis extension	J:135313
	abnormal somite development	J:135313
	craniorachischisis	J:135313
	open neural tube	J:135313
Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp2^tm1Aksh/Sfrp2^tm1Aksh Sfrp5^tm1Aksh/Sfrp5^tm1Aksh involves: 129 * C57BL/6	abnormal rostral-caudal axis patterning	J:135313
	decreased somite size	J:135313
	embryonic growth retardation	J:135313
	embryonic lethality, complete penetrance	J:135313
	fused somites	J:135313
	incomplete somite formation	J:135313
	open neural tube	J:135313
Sfrp2^C50F/Sfrp2^C50F Sfrp5^Q27stop/Sfrp5^Q27stop involves: BALB/c * C3H/HeH	abnormal seminiferous tubule morphology	J:119228
	kinked tail	J:119228
Sfrp2^tm1.1Brle/Sfrp2^tm1.1Brle Sfrp4^tm1.1Boer/Sfrp4^tm1.1Boer involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * BALB/cJ	increased litter size	J:275639
	increased ovulation rate	J:275639

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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