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Targeted Allele Detail
Symbol: Sfrp5tm1Aksh
Name: secreted frizzled-related sequence protein 5; targeted mutation 1, Akihiko Shimono
MGI ID: MGI:3793862
Gene: Sfrp5  Location: Chr19:42186410-42190691 bp, - strand  Genetic Position: Chr19, 35.93 cM, cytoband D1
Alliance: Sfrp5tm1Aksh page
Germline Transmission:  Earliest citation of germline transmission: J:135313
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe 5' coding region in the first exon encoding the cystein rich domain was replaced with a neo cassette followed by and IRES-YFP variant with multiple stop codons. (J:135313)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sfrp5 Mutation:  25 strains or lines available
Original:  J:135313 Satoh W, et al., Sfrp1, Sfrp2, and Sfrp5 regulate the Wnt/beta-catenin and the planar cell polarity pathways during early trunk formation in mouse. Genesis. 2008 Feb;46(2):92-103
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.13
The Jackson Laboratory