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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gdnf
glial cell line derived neurotrophic factor
MGI:107430
12 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Baxtm1Sjk/Baxtm1Sjk
Gdnftm1Rosl/Gdnf+
involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 		abnormal enteric neuron morphology J:82456
Bidtm1Sjk/Bidtm1Sjk
Gdnftm1Rosl/Gdnf+
involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 		abnormal enteric neuron morphology J:82456
Gdnftm1(cre/ERT2)Cos/Gdnf+
Gt(ROSA)26Sortm1(DTA)Jpmb/Gt(ROSA)26Sor+
involves: 129S6/SvEvTac * C57BL/6J 		abnormal kidney development J:206853
absent kidney J:206853
decreased renal glomerulus number J:206853
small kidney J:206853
Gdnftm1(cre/ERT2)Cos/Gdnf+
Gt(ROSA)26Sortm1(DTA)Jpmb/Gt(ROSA)26Sor+
Spry1tm1.1Jdli/Spry1+
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J 		small kidney J:206853
Gdnftm1Bbd/Gdnf+
Spry1tm1.1Jdli/Spry1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		normal renal/urinary system phenotype J:206853
Gdnftm1Lmgd/Gdnf+
Kif26btm1.1Ryn/Kif26b+
involves: 129 * C57BL/6 * C57BL/6J * CBA 		absent kidney J:160285
renal hypoplasia J:160285
Gdnftm1Rosl/Gdnf+
Slit2tm1Matl/Slit2tm1Matl
involves: 129S2/SvPas 		abnormal ureter morphology J:90324
Gdnftm1Rosl/Gdnf+
Itga8tm1Lfr/Itga8+
involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 		absent kidney J:122519
Gdnftm1Rosl/Gdnf+
Itga8tm1Lfr/Itga8tm1Lfr
involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 		abnormal kidney morphology J:122519
absent kidney J:122519
small kidney J:122519
Gdnftm1Rosl/Gdnf+
Nrtntm1Jmi/Nrtntm1Jmi
involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 		abnormal enteric neuron morphology J:82456
abnormal neurotransmitter secretion J:82456
intestinal hypoperistalsis J:82456
Gdnftm1Rosl/Gdnftm1Rosl
Nrtntm1Jmi/Nrtntm1Jmi
involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 		abnormal enteric ganglia morphology J:82456
Gdnftm2Bbd/Gdnf+
Spry1tm1.1Jdli/Spry1tm1.1Jdli
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * FVB/N 		abnormal kidney development J:96485
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory