59 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Chd7Gt(XK403)Byg/Chd7+ Tfap2atm1(cre)Moon/Tfap2a+ either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * CD-1)	normal embryo phenotype	J:154590
Fgf8tm1.4Mrt/Fgf8+ Tfap2atm1Will/Tfap2atm2.1Will involves: 129P2/OlaHsd * 129S1/Sv * Black Swiss	abnormal midface morphology	J:217408
	abnormal nasal pit morphology	J:217408
	cleft primary palate	J:217408
	unilateral cleft palate	J:217408
Fgf8tm1Mrc/Fgf8tm1Moon Tfap2atm1(cre)Moon/Tfap2a+ involves: 129/Sv * C57BL/6	abnormal blood vessel morphology	J:87304
	abnormal coronary artery morphology	J:87304
	abnormal craniofacial morphology	J:87304
	abnormal fourth pharyngeal arch artery morphology	J:87304
	abnormal neural crest cell apoptosis	J:87304
	abnormal pharyngeal arch artery morphology	J:87304
	abnormal subclavian artery morphology	J:87304
	absent fourth pharyngeal arch artery	J:87304
	absent sixth pharyngeal arch artery	J:87304
	enlarged third pharyngeal arch artery	J:87304
	fourth pharyngeal arch artery hypoplasia	J:87304
	interrupted aortic arch, type b	J:87304
	pharyngeal arch hypoplasia	J:87304
	postnatal lethality, complete penetrance	J:87304
	prenatal lethality, incomplete penetrance	J:87304
	retroesophageal right subclavian artery	J:87304
	right aortic arch	J:87304
Fgf8tm1Mrc/Fgf8tm2Mrc Tfap2atm1(cre)Moon/Tfap2a+ involves: 129/Sv * C57BL/6	abnormal blood vessel morphology	J:87304
	abnormal coronary artery morphology	J:87304
	abnormal craniofacial morphology	J:87304
	abnormal fourth pharyngeal arch artery morphology	J:87304
	abnormal neural crest cell apoptosis	J:87304
	abnormal pharyngeal arch artery morphology	J:87304
	abnormal subclavian artery morphology	J:87304
	absent fourth pharyngeal arch artery	J:87304
	absent sixth pharyngeal arch artery	J:87304
	enlarged third pharyngeal arch artery	J:87304
	fourth pharyngeal arch artery hypoplasia	J:87304
	interrupted aortic arch, type b	J:87304
	pharyngeal arch hypoplasia	J:87304
	postnatal lethality, complete penetrance	J:87304
	prenatal lethality, incomplete penetrance	J:87304
	retroesophageal right subclavian artery	J:87304
	right aortic arch	J:87304
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ Meis2tm1.1Zkoz/Meis2tm1.1Zkoz Tfap2atm1(cre)Moon/Tfap2a+ involves: 129 * C57BL/6J	abnormal cardiac neural crest cell morphology	J:229604
	abnormal cardiac outflow tract development	J:229604
	abnormal cartilage morphology	J:229604
	abnormal facial nerve morphology	J:229604
	abnormal heart valve morphology	J:229604
	abnormal hyoid bone morphology	J:229604
	abnormal mandible morphology	J:229604
	abnormal otic capsule morphology	J:229604
	abnormal palate morphology	J:229604
	abnormal parietal bone morphology	J:229604
	abnormal tongue muscle morphology	J:229604
	abnormal trigeminal nerve morphology	J:229604
	abnormal vestibulocochlear nerve morphology	J:229604
	absent interparietal bone	J:229604
	decreased cornea thickness	J:229604
	decreased tongue size	J:229604
	double outlet right ventricle	J:229604
	failure of eyelid fusion	J:229604
	neonatal lethality, complete penetrance	J:229604
	short mandible	J:229604
	small trigeminal ganglion	J:229604
Hoxb1tm5Mrc/Hoxb1tm7Mrc Tfap2atm1(cre)Moon/Tfap2a+ involves: 129S1/Sv * 129X1/SvJ	normal behavior/neurological phenotype	J:91364
	decreased motor neuron number	J:91364
Pknox1tm1.1Xzh/Pknox1tm1.1Xzh Tfap2atm1(cre)Moon/Tfap2a+ involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6	normal vision/eye phenotype	J:182769
Pygo2tm1.1Ssp/Pygo2tm1.2Ssp Tfap2atm1(cre)Moon/? involves: 129S1/Sv * 129X1/SvJ	abnormal lens induction	J:121416
	small lens	J:121416
Tbx1tm1Bld/Tbx1tm2.1Bem Tfap2atm1(cre)Moon/Tfap2a+ either: (involves: 129/Sv * C57BL/6 * SJL) or (involves: 129/Sv * C57BL/6J * CBA * SJL)	aberrant origin of the right subclavian artery	J:154590
	abnormal aortic arch morphology	J:154590
	abnormal cardiac outflow tract development	J:154590
	athymia	J:154590
	cleft palate	J:154590
	persistent truncus arteriosus	J:154590
	thymus hypoplasia	J:154590
	ventricular septal defect	J:154590
Tbx1tm2.1Bem/Tbx1+ Tfap2atm1(cre)Moon/Tfap2a+ either: (involves: 129/Sv * C57BL/6 * C57BL/6J * SJL) or (involves: 129/Sv * C57BL/6J * CBA * SJL)	fourth pharyngeal arch artery hypoplasia	J:154590
Tfap2atm1Hsv/Tfap2atm2Will Tfap2ctm1Will/Tfap2ctm2Will Tg(Zp3-cre)3Mrt/0 involves: 129S1/Sv * FVB/N	normal embryo phenotype	J:113442
	embryonic lethality between implantation and somite formation, incomplete penetrance	J:113442
Tfap2atm2Will/Tfap2a+ Tfap2ctm1Will/Tfap2ctm2Will Tg(Zp3-cre)3Mrt/0 involves: 129S1/Sv * FVB/N	abnormal embryonic tissue morphology	J:113442
	abnormal extraembryonic tissue morphology	J:113442
	decreased embryo size	J:113442