Zbtb7b Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Zbtb7b
zinc finger and BTB domain containing 7B
MGI:102755

9 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
B2m^tm1Jae/B2m^tm1Jae Zbtb7b^tm1Litt/Zbtb7b^tm1.2Litt involves: 129S2/SvPas * C57BL/6	abnormal CD8-positive, alpha-beta T cell differentiation	J:141144
	abnormal double-positive T cell morphology	J:141144
B2m^tm1Unc/B2m^tm1Unc Zbtb7b^tm4.1Itan/Zbtb7b^tm4.1Itan involves: 129P2/OlaHsd	increased CD8-positive, alpha-beta T cell number	J:193321
Cbfb^tm1Itan/Cbfb^tm1Itan Zbtb7b^tm2Litt/Zbtb7b⁺ Tg(Lck-cre)1Cwi/0 involves: 129P2/OlaHsd * C57BL/6	abnormal T cell differentiation	J:141144
	decreased CD4-positive, alpha-beta T cell number	J:141144
Cbfb^tm1Itan/Cbfb^tm1Itan Zbtb7b^tm2Litt/Zbtb7b^tm1.2Litt Tg(Lck-cre)1Cwi/0 involves: 129P2/OlaHsd * C57BL/6	abnormal T cell differentiation	J:141144
	decreased CD4-positive, alpha-beta T cell number	J:141144
Cd8a^tm1Mak/Cd8a^tm1Mak Zbtb7b^hd/Zbtb7b^hd involves: B6.129S2-Cd8a^tm1Mak * B6.Cg-Thpok^hd	absent CD4-positive, alpha-beta T cells	J:95867
Rr96^tm2Litt/Rr96⁺ Zbtb7b^tm1Tani/Zbtb7b^tm1Tani involves: 129 * 129P2/OlaHsd * C57BL/6	increased double-negative T cell number	J:141142
Rr96^tm2Litt/Rr96⁺ Zbtb7b^tm1Itan/Zbtb7b^tm1Tani involves: 129 * 129P2/OlaHsd * C57BL/6	abnormal double-negative T cell morphology	J:141142
	decreased CD8-positive, alpha-beta T cell number	J:141142
Tg(CD2-Zbtb7b)C8Rbo/? Tg(TcraH-Y,TcrbH-Y)71Vbo/? involves: C57BL/6 * DBA/2J	abnormal T cell differentiation	J:97610
Tg(CD2-Zbtb7b)C8Rbo/? Tg(TcrLCMV)327Sdz/? involves: C57BL/6 * DBA/2J	abnormal T cell differentiation	J:97610
Tg(CD2-Zbtb7b)C8Rbo/? Themis^tm1Lov/Themis^tm1Lov involves: 129	abnormal T cell differentiation	J:151075
Tg(TcrAND)53Hed/? Zbtb7b^tm1.1Rbo/Zbtb7b^tm1.1Rbo involves: C57BL/6 * SJL	abnormal T cell differentiation	J:141145

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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