Gys1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gys1
glycogen synthase 1, muscle
MGI:101805

44 phenotypes from 6 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gys1^em1(IMPC)Bay/Gys1⁺ C57BL/6N-Gys1^em1(IMPC)Bay/BayMmucd	decreased body length	J:211773
Gys1^em1(IMPC)Bay/Gys1⁺ C57BL/6N-Gys1^em1(IMPC)Bay/BayMmucd	increased bone mineral content	J:211773
Gys1^em1(IMPC)Bay/Gys1^em1(IMPC)Bay C57BL/6N-Gys1^em1(IMPC)Bay/BayMmucd	abnormal embryo size	J:211773
	abnormal skin coloration	J:211773
	edema	J:211773
	preweaning lethality, complete penetrance	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Gys1^{Gt(OST33395)Lex}/Gys1^{Gt(OST33395)Lex} involves: 129S5/SvEvBrd * 129X1/SvJ * C57BL/6J	abnormal blood circulation	J:92245
	abnormal fetal cardiomyocyte proliferation	J:92245
	abnormal heart ventricle morphology	J:92245
	abnormal interventricular septum morphology	J:92245
	abnormal pericardial cavity morphology	J:92245
	blood vessel congestion	J:92245
	cardiac fibrosis	J:92245
	decreased glycogen level	J:92245
	dilated heart atrium	J:92245
	increased heart weight	J:92245
	liver hemorrhage	J:92245
	neonatal lethality, incomplete penetrance	J:92245
	pulmonary vascular congestion	J:92245
	thin ventricular wall	J:92245
	trabecula carnea hypoplasia	J:92245
Gys1^tm1.1Arte/Gys1⁺ involves: C57BL/6J	abnormal glycogen homeostasis	J:167911
Gys1^tm1.1Arte/Gys1⁺ involves: C57BL/6J	decreased skeletal muscle glycogen level	J:167911
Gys1^tm1.1Arte/Gys1^tm1.1Arte involves: C57BL/6J	abnormal glycogen homeostasis	J:167911
	abnormal muscle cell glucose uptake	J:167911
	decreased skeletal muscle glycogen level	J:167911
	normal growth/size/body region phenotype	J:167911
	normal homeostasis/metabolism phenotype	J:167911
	increased glycogen catabolism rate	J:167911
Gys1^{tm1a(EUCOMM)Wtsi}/Gys1^{tm1a(EUCOMM)Wtsi} involves: C57BL/6J * C57BL/6NTac	normal nervous system phenotype	J:216806
	perinatal lethality, incomplete penetrance	J:216806
Gys1^{tm1a(EUCOMM)Wtsi}/Gys1^{tm1a(EUCOMM)Wtsi} involves: C57BL/6N	abnormal lung morphology	J:300001
	decreased lung glycogen level	J:300001
Gys1^{tm1c(EUCOMM)Wtsi}/Gys1^{tm1c(EUCOMM)Wtsi} Tg(Nes-cre)1Kln/0 involves: C57BL/6 * C57BL/6J * C57BL/6N * SJL	abnormal operant conditioning behavior	J:218886
	decreased brain glycogen level	J:218886
	enhanced paired-pulse facilitation	J:218886
	impaired synaptic plasticity	J:218886
	normal nervous system phenotype	J:218886
	reduced long-term potentiation	J:218886
Hprt1^{tm1(CAG-Gys1)Jjg}/? Myl1^tm1(cre)Sjb/Myl1⁺ involves: 129P2/OlaHsd 129S1/Sv * 129X1/SvJ	abnormal cellular respiration	J:244440
	abnormal response to exercise	J:244440
	decreased aerobic running capacity	J:244440
	impaired exercise endurance	J:244440
	increased skeletal muscle glycogen level	J:244440
Hprt1^{tm1(CAG-Gys1*)Jjg}/? Tg(Nes-cre)1Kag/? involves: 129P2/OlaHsd	impaired autophagy	J:210491
	increased brain glycogen level	J:210491

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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