Hprt1tm1(CAG-Gys1*)Jjg
Targeted Allele Detail
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Symbol: |
Hprt1tm1(CAG-Gys1*)Jjg |
Name: |
hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, Joan J Guinovart |
MGI ID: |
MGI:5618914 |
Synonyms: |
mMGS-9A |
Gene: |
Hprt1 Location: ChrX:52077014-52110536 bp, + strand Genetic Position: ChrX, 29.31 cM, cytoband A6
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Alliance: |
Hprt1tm1(CAG-Gys1*)Jjg page
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Germline Transmission: |
Earliest citation of germline transmission:
J:218887
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Parent Cell Line: |
E14 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Conditional ready, Constitutively active, Inserted expressed sequence) |
Mutation: |
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Insertion
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Hprt1tm1(CAG-Gys1*)Jjg expresses
1 gene
Knock-in expresses:
Organism |
Expressed Gene |
Note |
mouse |
Gys1 (MGI:101805) |
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Mutation details: The CAG promoter, a floxed stop cassette and a mutated cDNA encoding a murine Gys1 gene with the 9 regulatory serines mutated to alanine were inserted into the locus via homologous recombination.
(J:218887)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Hprt1 Mutation: |
1274 strains or lines available
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Original: |
J:218887 Duran J, et al., Deleterious effects of neuronal accumulation of glycogen in flies and mice. EMBO Mol Med. 2012 Aug;4(8):719-29 |
All: |
3 reference(s) |
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