Serpina3k
Gene Detail

Symbol Name ID

Serpina3k serine (or cysteine) peptidase inhibitor, clade A, member 3K MGI:98377

Synonyms

1300001I07Rik, alpha-1 antiproteinase, contrapsin, D12Rp54, MMCM2, MMSpi2, RP54, Spi2, Spi-2

Feature Type

protein coding gene

Genetic Map

Chromosome 12

53.99 cM, cytoband F1
Detailed Genetic Map ± 1 cM


Mapping data(12)

Sequence Map

Chr12:104338486-104345741 bp, + strand From VEGA annotation of GRCm38   7256 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:40659  Vertebrate Homology Class
3 mouse; 1 rat

Protein SuperFamily: serpin
Gene Tree: Serpina3k

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	negative regulation of endopeptidase activity, negative regulation of peptidase activity, ...
Component	extracellular region
Function	peptidase inhibitor activity, serine-type endopeptidase inhibitor activity

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (50)    Tissues (10)    Images (20)
Theiler Stages: 23, 26, 28

Assay Type	Results
RNA in situ	36
Northern blot	14

cDNA source data(15)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(19) Genomic(1) cDNA(17) Other(1)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000035427 (Evidence)
Ensembl Gene Model	ENSMUSG00000058207 (Evidence)
Entrez Gene	20714 (Evidence)
DoTS	DT.101318263, DT.101407741, DT.40150689
Consensus CDS Project	CCDS36537.1
International Mouse Knockout Project Status	Serpina3k

Sequences

Length	Strain/Species
genomic	OTTMUSG00000035427	VEGA Gene Model | MGI Sequence Detail	7256	C57BL/6J
transcript	OTTMUST00000090585	VEGA | MGI Sequence Detail	1654	Not Applicable
polypeptide	OTTMUSP00000049729	VEGA | MGI Sequence Detail	418	Not Applicable

All sequences(25) RefSeq(2) UniProt(1)

Polymorphisms

RFLP(6) : SNPs(155 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR023795	Protease inhibitor I4, serpin, conserved site
InterPro	IPR023796	Serpin domain
InterPro	IPR000215	Serpin family
Protein Ontology	PR:000015938	serine protease inhibitor A3K

References

(Earliest) J:5549 Wilcox FH, Genetic variation in plasma prealbumin of the house mouse. J Hered. 1975 Jan-Feb;66(1):19-22
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(46)

Other accession IDs

MGD-MRK-14022, MGD-MRK-14521, MGD-MRK-14526, MGD-MRK-3357, MGI:1915688