Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable serine-type endopeptidase inhibitor activity. Acts upstream of or within response to cytokine and response to peptide hormone. Located in collagen-containing extracellular matrix. Is expressed in axial skeleton; liver; nervous system; and thymus primordium. Human ortholog(s) of this gene implicated in chronic obstructive pulmonary disease; cystic fibrosis; and vasculitis. Orthologous to human SERPINA3 (serpin family A member 3).