Snrpn
Gene Detail

Symbol

Name
ID

Snrpn
small nuclear ribonucleoprotein N
MGI:98347

Synonyms

2410045I01Rik, MGC:18604, MGC:30325, Peg4, Pwcr1

Feature Type

protein coding gene

Genetic Map

Chromosome 7
34.04 cM
Detailed Genetic Map ± 1 cM


Mapping data(17)

Sequence Map

Chr7:59982502-60140219 bp, - strand From NCBI annotation of GRCm38   157718 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate
homology

HomoloGene:68297  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: small nuclear ribonucleoprotein associated protein, SmB/SmN types

Human
homologs

Human Homolog		SNRPN, small nuclear ribonucleoprotein polypeptide N
NCBI Gene ID		6638
neXtProt AC		NX_P63162
Human Synonyms		HCERN3, PWCR, RT-LI, SM-D, sm-N, SMN, SNRNP-N, SNURF-SNRPN
Human Chr (Location)		15q11.2; chr15:24823647-24978582 (+)  GRCh38
Disease Associations		(2) Diseases Associated with Human SNRPN

Mutations,
alleles, and
phenotypes

All mutations/alleles(17) : Gene trapped(3) Targeted(13) Transgenic(1)
Genomic Mutations involving Snrpn (3)
Incidental mutations (data from Mutagenetix , APF )
 

Homozygotes for targeted intragenic deletions are phenotypically normal. Deletions that also encompass neighboring genes on the paternal chromosome exhibit growth retardation, hypotonia, and high mortality.

 
Human Diseases Modeled in Mice Using Snrpn (2)    Mutations Annotated to Human Diseases (5)   

Interactions

Snrpn interacts with 141 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)

View All

Gene Ontology
(GO)
classifications

All GO classifications: (3 annotations)

Component

nucleus, U1 snRNP, ...

External Resources: FuncBase

Expression

Literature Summary: (34 records)

Data Summary: Results (259)    Tissues (33)    Images (31)    Tissue x Stage Matrix (view)

Assay Type	Results
RNA in situ	221
Northern blot	23
RT-PCR	15

cDNA source data(10)
External Resources: Allen Institute   GEO   Expression Atlas

Molecular
reagents

All nucleic(31) Genomic(9) cDNA(14) Primer pair(7) Other(1)
Microarray probesets(5)

Other database
links

Ensembl Gene Model	ENSMUSG00000000948 (Evidence), ENSMUSG00000102252 (Evidence)
Entrez Gene	20646 (Evidence)
Consensus CDS Project	CCDS39974.1
International Mouse Knockout Project Status	Snrpn

Sequences

Length	Strain/Species
genomic	20646	NCBI Gene Model | MGI Sequence Detail	157718	C57BL/6J
transcript	NM_001082962	RefSeq | MGI Sequence Detail	2076	C57BL/6
polypeptide	NP_038698	RefSeq | MGI Sequence Detail	240	C57BL/6

All sequences(47) RefSeq(6)

Polymorphisms

All PCR and RFLP(7) : PCR(1) RFLP(6) SNPs within 2kb(1874 from dbSNP Build 137)    SNPs within 2kb including multiple locations(1876)

Protein-related
information

Resource	ID	Description
Protein Ontology	PR:000015349	small nuclear ribonucleoprotein-associated protein N

References

(Earliest) J:2311 Gerrelli D, et al., Cloning and sequencing of a mouse embryonal carcinoma cell mRNA encoding the tissue specific RNA splicing protein SmN. Nucleic Acids Res. 1991 Dec 11;19(23):6642
(Latest) J:206605 Faisal M, et al., Sexual differences of imprinted genes' expression levels. Gene. 2014 Jan 1;533(1):434-8
All references(118)
Disease annotation references (4)

Other
accession IDs

MGD-MRK-14477, MGI:1923808