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Snrpn
Gene Detail
 Symbol
Name
ID
Snrpn
small nuclear ribonucleoprotein N
MGI:98347
Synonyms 2410045I01Rik, MGC:18604, MGC:30325, Peg4, Pwcr1
Feature Type protein coding gene
Genetic Map
Chromosome 7
34.04 cM
Detailed Genetic Map ± 1 cM


Mapping data(17)
Sequence Map
Chr7:59982495-60005111 bp, - strand
From VEGA annotation of GRCm38

  22617 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68297  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: small nuclear ribonucleoprotein associated protein, SmB/SmN types
Gene Tree: Snrpn

Human
homologs
Human Homolog SNRPN, small nuclear ribonucleoprotein polypeptide N
NCBI Gene ID 6638
neXtProt AC  NX_P63162
Human Synonyms  HCERN3, PWCR, RT-LI, SM-D, sm-N, SMN, SNRNP-N, SNURF-SNRPN
Human Chr (Location)  15q11.2; chr15:24823647-24978582 (+)  GRCh38
Disease Associations  (2) Diseases Associated with Human SNRPN
Alleles
and
phenotypes
All alleles(14) : Gene trapped(3) Targeted(11)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygotes for targeted intragenic deletions are phenotypically normal. Deletions that also encompass neighboring genes on the paternal chromosome exhibit growth retardation, hypotonia, and high mortality.
 
Human Diseases Modeled Using Mouse Snrpn (2)    Alleles Annotated to Human Diseases(3)   
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Component nucleus, ribonucleoprotein complex, ...
Function RNA binding
External Resources: FuncBase
Expression
Literature Summary: (32 records)
Data Summary: Results (259)    Tissues (33)    Images (31)
Theiler Stages: 15, 17, 20, 21, 23, 26, 28
Assay TypeResults
RNA in situ 221
Northern blot 23
RT-PCR 15
cDNA source data(10)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(31) Genomic(9) cDNA(14) Primer pair(7) Other(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000042349 (Evidence)
Ensembl Gene ModelENSMUSG00000000948 (Evidence)
Entrez Gene20646 (Evidence)
Consensus CDS ProjectCCDS39974.1
International Mouse Knockout Project StatusSnrpn
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000042349 VEGA Gene Model | MGI Sequence Detail 22617 C57BL/6J ±  kb
transcript OTTMUST00000111612 VEGA | MGI Sequence Detail 1932 Not Applicable 
polypeptide OTTMUSP00000062525 VEGA | MGI Sequence Detail 240 Not Applicable 

For the selected sequences
All sequences(45) RefSeq(6) UniProt(2)
Polymorphisms All PCR and RFLP(7) : PCR(1) RFLP(6) SNPs within 2kb(1873 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR010920 Like-Sm (LSM) domain
InterPro IPR001163 Ribonucleoprotein LSM domain
InterPro IPR006649 Ribonucleoprotein LSM domain, eukaryotic/archaea-type
InterPro IPR017131 Small ribonucleoprotein associated, SmB/SmN
Protein Ontology PR:000015349 small nuclear ribonucleoprotein-associated protein N
References (Earliest) J:2311 Gerrelli D, et al., Cloning and sequencing of a mouse embryonal carcinoma cell mRNA encoding the tissue specific RNA splicing protein SmN. Nucleic Acids Res. 1991 Dec 11;19(23):6642
(Latest) J:198496 Resnick JL, et al., Recommendations for the investigation of animal models of Prader-Willi syndrome. Mamm Genome. 2013 Jun;24(5-6):165-78
All references(120)
Other
accession IDs
MGD-MRK-14477, MGI:1923808

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory