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Ptprd Gene Detail
Summary
  • Symbol
    Ptprd
  • Name
    protein tyrosine phosphatase, receptor type, D
  • Synonyms
    1110002J03Rik, 3000002J10Rik, B230219D21Rik, MGC:36851
  • Feature Type
    protein coding gene
  • IDs
    MGI:97812
    NCBI Gene: 19266
Location & Maps
more
  • Sequence Map
    Chr4:75941238-78211961 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      2270724 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 36.94 cM
  • Mapping Data
    5 experiments
Homology
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    16 phenotypes from multigenic genotypes
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    11
  • Chemically induced (other)
    2
  • Gene trapped
    4
  • Radiation induced
    1
  • Targeted
    4
  • Genomic Mutations
    3 involving Ptprd
  • Incidental Mutations
Homozygotes for a targeted null mutation exhibit impaired learning of spatial tasks, enhanced long-term potentiation at hippocampal synapses, and high mortality associated with reduced food intake.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000304 VEGA Gene Model | MGI Sequence Detail 2270724 C57BL/6J ±  kb
transcript OTTMUST00000095795 VEGA | MGI Sequence Detail 9899 Not Applicable  
polypeptide OTTMUSP00000053476 VEGA | MGI Sequence Detail 1912 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    24915 from dbSNP Build 142
  • RFLP
Protein
Information
less
Molecular
Reagents
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  • All nucleic 37
    cDNA 36
    Primer pair 1

    Microarray probesets 12
Other
Accession IDs
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MGD-MRK-13681, MGI:1917472, MGI:1919036, MGI:2444522
References
more
  • Summaries
    All 57
    Developmental Gene Expression 17
    Gene Ontology 5
    Phenotypes 13
  • Earliest
    J:14172 Mizuno K, et al., MPTP delta, a putative murine homolog of HPTP delta, is expressed in specialized regions of the brain and in the B-cell lineage. Mol Cell Biol. 1993 Sep;13(9):5513-23
  • Latest
    J:229257 Gu Z, et al., Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. PLoS One. 2015;10(3):e0121550

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory