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Mog
Gene Detail
Symbol

Name
ID
Mog
myelin oligodendrocyte glycoprotein
MGI:97435
Synonyms
B230317G11Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 17
19.16 cM, cytoband C
Detailed Genetic Map ± 1 cM


Mapping data(9)
Sequence Map
Chr17:37010743-37023398 bp, - strand
From VEGA annotation of GRCm38

  12656 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:111009  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 14 chicken

HCOP human homology predictions: MOG
Protein SuperFamily: myelin-oligodendrocyte glycoprotein
Gene Tree: Mog

Human
homologs
MOG, myelin oligodendrocyte glycoprotein
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 4340
neXtProt AC: NX_Q16653

Human Synonyms: BTN6, BTNL11, MOGIG2, NRCLP7

Human Chr (Location): 6p22.1; chr6:29656981-29672372 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human MOG

Mutations,
alleles, and
phenotypes
All mutations/alleles(75) : Gene trapped(68) Targeted(7)
Genomic Mutations involving Mog (1)
Incidental mutations (data from Mutagenetix , APF )
 
While one line of homozygous mutant mice showed resistance to experimental autoimmune encephalomyelitis (EAE), another showed increased susceptibility.
 
Mutations Annotated to Human Diseases (2)    Phenotype Images(1)
Interactions
Mog interacts with 124 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (8 records)
Data Summary: Results (10)    Tissues (4)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 10
cDNA source data(16)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(46) Genomic(20) cDNA(19) Primer pair(4) Other(3)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000014932 (Evidence)
Ensembl Gene Model ENSMUSG00000076439 (Evidence)
Entrez Gene 17441 (Evidence)
UniGene 210857
DFCI TC1580292, TC1730504
DoTS DT.55248242, DT.60104903
NIA Mouse Gene Index U037780
PDB 1PY9
Consensus CDS Project CCDS28734.1
International Mouse Phenotyping Consortium Status Mog
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000014932 VEGA Gene Model | MGI Sequence Detail 12656 C57BL/6J ±  kb
transcript OTTMUST00000035462 VEGA | MGI Sequence Detail 1704 Not Applicable 
polypeptide OTTMUSP00000015874 VEGA | MGI Sequence Detail 247 Not Applicable 

For the selected sequences
All sequences(45) RefSeq(10) UniProt(5)
Polymorphisms
All PCR and RFLP(2) : PCR(1) RFLP(1) SNPs within 2kb(58 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR013106 Immunoglobulin V-set
InterPro IPR016663 Myelin-oligodendrocyte glycoprotein
Protein Ontology PR:000010514 myelin-oligodendrocyte glycoprotein
References
(Earliest) J:849 Amiguet P, et al., Purification and partial structural and functional characterization of mouse myelin/oligodendrocyte glycoprotein. J Neurochem. 1992 May;58(5):1676-82
(Latest) J:221642 Klingler E, et al., The cytoskeleton-associated protein SCHIP1 is involved in axon guidance, and is required for piriform cortex and anterior commissure development. Development. 2015 Jun 1;142(11):2026-36
All references(75)
Other
accession IDs
MGD-MRK-13032, MGI:2443229

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory