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Mog
Gene Detail
 Symbol
Name
ID
Mog
myelin oligodendrocyte glycoprotein
MGI:97435
Synonyms B230317G11Rik
Feature Type protein coding gene
Genetic Map
Chromosome 17
19.16 cM, cytoband C
Detailed Genetic Map ± 1 cM


Mapping data(9)
Sequence Map
Chr17:37010746-37023398 bp, - strand
From VEGA annotation of GRCm38

  12653 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:111009  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 14 chicken

Protein SuperFamily: myelin-oligodendrocyte glycoprotein
Gene Tree: Mog

Human
homologs
Human Homolog MOG, myelin oligodendrocyte glycoprotein
NCBI Gene ID 4340
neXtProt AC  NX_Q16653
Human Synonyms  BTN6, BTNL11, MOGIG2, NRCLP7
Human Chr (Location)  6p22.1; chr6:29656981-29672372 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human MOG
Alleles
and
phenotypes
All alleles(72) : Gene trapped(67) Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
While one line of homozygous mutant mice showed resistance to experimental autoimmune encephalomyelitis (EAE), another showed increased susceptibility.
 
Alleles Annotated to Human Diseases(2)   
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process cell adhesion, positive regulation of MyD88-dependent toll-like receptor signaling pathway
Component integral component of membrane, membrane
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (10)    Tissues (3)    Images (1)
Theiler Stages: 26, 28
Assay TypeResults
RT-PCR 10
cDNA source data(16)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(46) Genomic(20) cDNA(19) Primer pair(4) Other(3)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000014932 (Evidence)
Ensembl Gene ModelENSMUSG00000076439 (Evidence)
Entrez Gene17441 (Evidence)
UniGene210857
DFCITC1580292, TC1730504
DoTSDT.55248242, DT.60104903
NIA Mouse Gene IndexU037780
PDB1PY9
Consensus CDS ProjectCCDS28734.1
International Mouse Knockout Project StatusMog
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000014932 VEGA Gene Model | MGI Sequence Detail 12653 C57BL/6J ±  kb
transcript OTTMUST00000035462 VEGA | MGI Sequence Detail 1701 Not Applicable 
polypeptide OTTMUSP00000015874 VEGA | MGI Sequence Detail 247 Not Applicable 

For the selected sequences
All sequences(57) RefSeq(22) UniProt(5)
Polymorphisms All PCR and RFLP(2) : PCR(1) RFLP(1) SNPs within 2kb(58 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR013106 Immunoglobulin V-set
InterPro IPR003596 Immunoglobulin V-set, subgroup
InterPro IPR016663 Myelin-oligodendrocyte glycoprotein
Protein Ontology PR:000010514 myelin-oligodendrocyte glycoprotein
References (Earliest) J:849 Amiguet P, et al., Purification and partial structural and functional characterization of mouse myelin/oligodendrocyte glycoprotein. J Neurochem. 1992 May;58(5):1676-82
(Latest) J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
All references(72)
Other
accession IDs
MGD-MRK-13032, MGI:2443229

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory