Homozygous inactivation of this gene leads to altered arterial wall structure, aortic aneurysms, cardiovascular dysfunction, diaphragmatic hernia, and perinatal death. Abnormal development of the respiratory system, and elastic and collagen fiber abnormalities in the lung and skin are also observed.
|Ensembl Gene Model||ENSMUSG00000024529 (Evidence)|
|Entrez Gene||16948 (Evidence)|
|DFCI||TC1572418, TC1602062, TC1660725, TC1701133|
|DoTS||DT.533823, DT.94139675, DT.94303779, DT.97333987|
|NIA Mouse Gene Index||U038427|
|Consensus CDS Project||CCDS50289.1|
|International Mouse Phenotyping Consortium Status||Lox|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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