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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Lox
lysyl oxidase
MGI:96817
56 phenotypes from 5 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Loxb2b370.2Clo/Loxb2b370.2Clo
C57BL/6J-Loxb2b370.2Clo
abnormal blood vessel morphology J:175213
diaphragmatic hernia J:175213
heart left ventricle hypertrophy J:175213
heart right ventricle hypertrophy J:175213
pulmonary artery stenosis J:175213
supravalvar aortic stenosis J:175213
Loxem1(IMPC)Mbp/Lox+
C57BL/6N-Loxem1(IMPC)Mbp/MbpMmucd
abnormal caudal vertebrae morphology J:211773
abnormal kidney morphology J:211773
abnormal placenta morphology J:211773
abnormal skin morphology J:211773
abnormal spleen morphology J:211773
enlarged spleen J:211773
small kidney J:211773
Loxem1(IMPC)Mbp/Loxem1(IMPC)Mbp
C57BL/6N-Loxem1(IMPC)Mbp/MbpMmucd
abnormal craniofacial morphology J:211773
edema J:211773
preweaning lethality, complete penetrance J:211773
Loxtm1.1Khki/Loxtm1.1Khki
involves: C57BL/6
decreased tumor latency J:264295
increased incidence of tumors by chemical induction J:264295
increased lymphocyte cell number J:264295
increased susceptibility to induced morbidity/mortality J:264295
Loxtm1Ikh/Loxtm1Ikh
involves: 129X1/SvJ * C57BL/6J
abnormal aorta elastic tissue morphology J:82926
abnormal aorta smooth muscle morphology J:82926
abnormal aorta wall morphology J:82926
abnormal blood vessel elastic tissue morphology J:82926
abnormal descending thoracic aorta morphology J:82926
abnormal diaphragm central tendon morphology J:82926
abnormal diaphragm development J:82926
aortic aneurysm J:82926
decreased aorta elastin content J:82926
decreased aorta wall thickness J:82926
decreased skin tensile strength J:82926
diaphragmatic hernia J:82926
hemoperitoneum J:82926
hemothorax J:82926
perinatal lethality, complete penetrance J:82926
Loxtm1Soin/Loxtm1Soin
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal aorta elastic tissue morphology J:103389
abnormal aorta smooth muscle morphology J:103389
abnormal blood flow velocity J:103389
abnormal bronchiole epithelium morphology J:101687
abnormal cutaneous collagen fibril morphology J:101687
abnormal cutaneous elastic fiber morphology J:101687
abnormal diaphragm morphology J:101687
abnormal enzyme/coenzyme activity J:101687
abnormal pulmonary acinus morphology J:101687
abnormal pulmonary artery morphology J:101687
abnormal pulmonary elastic fiber morphology J:101687
abnormal suckling behavior J:103389
aorta stenosis J:103389
aortic aneurysm J:103389
atelectasis J:101687
cyanosis J:103389
decreased locomotor activity J:103389
decreased lung weight J:101687
diaphragmatic hernia J:101687
dilated respiratory conducting tube J:101687
emphysema J:101687
hemorrhage J:103389
impaired branching involved in respiratory bronchiole morphogenesis J:101687
impaired branching involved in terminal bronchiole morphogenesis J:101687
perinatal lethality, complete penetrance J:103389
pulmonary hypoplasia J:101687
semilunar valve regurgitation J:103389

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory