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Hoxb9
Gene Detail
 Symbol
Name
ID
Member of
Hoxb9
homeobox B9
MGI:96190
Hoxb cluster
Synonyms Hox-2.5
Feature Type protein coding gene
Genetic Map
Chromosome 11
59.81 cM
Detailed Genetic Map ± 1 cM


Mapping data(9)
Sequence Map
Chr11:96271457-96276595 bp, + strand
From VEGA annotation of GRCm38

  5139 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7367  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: homeobox protein, Hox9 type
Gene Tree: Hoxb9

Human
homologs
Human Homolog HOXB9, homeobox B9
NCBI Gene ID 3219
neXtProt AC  NX_P17482
Human Synonyms  HOX2, HOX-2.5, HOX2E
Human Chr (Location)  17q21.3; chr17:48621156-48626473 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(1) Targeted(3)
Genomic Mutations involving Hoxb9 (1)
Incidental mutations (data from APF )
 
Mutations affect developing thoracic skeletal elements. Homozygotes exhibit rib fusion, abnormal rib attachment to the sternum, and reduced intercostal segments of the sternum. Homozygotes or heterozygotes may show an eighth rib attached to the sternum.
 
Interactions
Hoxb9 interacts with 194 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (22 annotations)
Process anterior/posterior pattern specification, canonical Wnt signaling pathway, ...
Component mitochondrion, nucleus
Function DNA binding, sequence-specific DNA binding
External Resources: FuncBase
Expression
Literature Summary: (51 records)
Data Summary: Results (227)    Tissues (151)    Images (62)
Theiler Stages: 11, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 28
Assay TypeResults
RNA in situ 154
Northern blot 16
RT-PCR 53
RNase protection 4
cDNA source data(15)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(42) Genomic(17) cDNA(19) Primer pair(5) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000001991 (Evidence)
Ensembl Gene ModelENSMUSG00000020875 (Evidence)
Entrez Gene15417 (Evidence)
UniGene258271
DFCITC1593596, TC1596739, TC1607117, TC1663637, TC1687897
DoTSDT.526633, DT.110533219, DT.110533220, DT.94230149
NIA Mouse Gene IndexU013242
Consensus CDS ProjectCCDS25292.1
International Mouse Knockout Project StatusHoxb9
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001991 VEGA Gene Model | MGI Sequence Detail 5139 C57BL/6J ±  kb
transcript OTTMUST00000003997 VEGA | MGI Sequence Detail 2574 Not Applicable 
polypeptide OTTMUSP00000001934 VEGA | MGI Sequence Detail 250 Not Applicable 

For the selected sequences
All sequences(36) RefSeq(2) UniProt(3)
Polymorphisms PCR(2) : SNPs within 2kb(36 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017970 Homeobox, conserved site
InterPro IPR017112 Homeobox protein Hox9
InterPro IPR001356 Homeodomain
InterPro IPR009057 Homeodomain-like
InterPro IPR020479 Homeodomain, metazoa
InterPro IPR006711 Hox9, N-terminal activation domain
Protein Ontology PR:000008706 homeobox protein Hox-B9
References (Earliest) J:32282 Graham A, et al., Characterization of a murine homeo box gene, Hox-2.6, related to the Drosophila Deformed gene. Genes Dev. 1988 Nov;2(11):1424-38
(Latest) J:196334 Harima Y, et al., Accelerating the tempo of the segmentation clock by reducing the number of introns in the Hes7 gene. Cell Rep. 2013 Jan 31;3(1):1-7
All references(94)
Other
accession IDs
MGD-MRK-10833, MGD-MRK-10891

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory