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H2-Eb2 Gene Detail
Summary
  • Symbol
    H2-Eb2
  • Name
    histocompatibility 2, class II antigen E beta2
  • Synonyms
    A130038H09Rik, H-2Eb2, Ia5, Ia-5
  • Feature Type
    protein coding gene
  • IDs
    MGI:95902
    NCBI Gene: 381091
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:34325665-34341412 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 17.98 cM
  • Mapping Data
    5 experiments
  • Sequence Tag
Strain
Comparison
more
  • SNPs within 2kb
    4 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_95902
protein coding gene Chr17:34325503-34341412 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023570
protein coding gene Chr17:34334852-34349993 (+)
A/J MGP_AJ_G0023532
protein coding gene Chr17:33166962-33182025 (+)
AKR/J MGP_AKRJ_G0023497
protein coding gene Chr17:33556511-33572874 (+)
BALB/cJ MGP_BALBcJ_G0023536
protein coding gene Chr17:33327607-33342335 (+)
C3H/HeJ MGP_C3HHeJ_G0023296
protein coding gene Chr17:33914116-33929246 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023976
protein coding gene Chr17:35619970-35634307 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021455
protein coding gene Chr17:31134119-31150812 (+)
CAST/EiJ MGP_CASTEiJ_G0022796
protein coding gene Chr17:34000996-34015378 (+)
CBA/J MGP_CBAJ_G0023274
protein coding gene Chr17:37087133-37103543 (+)
DBA/2J MGP_DBA2J_G0023403
protein coding gene Chr17:32512428-32526758 (+)
FVB/NJ MGP_FVBNJ_G0023369
protein coding gene Chr17:32369391-32384276 (+)
LP/J MGP_LPJ_G0023480
protein coding gene Chr17:34593757-34609197 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023392
protein coding gene Chr17:36057481-36073404 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024019
protein coding gene Chr17:33887968-33902340 (+)
PWK/PhJ MGP_PWKPhJ_G0022546
protein coding gene Chr17:31450336-31465511 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022361
protein coding gene Chr17:31850383-31864629 (+)
WSB/EiJ MGP_WSBEiJ_G0022857
protein coding gene Chr17:33927246-33943920 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
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Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000067341 Ensembl Gene Model | MGI Sequence Detail 15748 C57BL/6J ±  kb
transcript ENSMUST00000050325 Ensembl | MGI Sequence Detail 3392 Not Applicable  
polypeptide ENSMUSP00000056814 Ensembl | MGI Sequence Detail 287 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • InterPro Domains
    IPR003597 Immunoglobulin C1-set
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
    IPR011162 MHC classes I/II-like antigen recognition protein
    IPR014745 MHC class II, alpha/beta chain, N-terminal
    IPR000353 MHC class II, beta chain, N-terminal
Molecular
Reagents
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  • All nucleic 37
    Genomic 27
    cDNA 6
    Primer pair 1
    Other 3

    Microarray probesets 2
Other
Accession IDs
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MGD-MRK-10385, MGD-MRK-10498, MGD-MRK-11048, MGD-MRK-11053, MGI:3588187
References
more
  • Summaries
    All 42
    Phenotypes 5
  • Earliest
    J:5895 Delovitch TL, et al., Immunochemical evidence for three Ia loci in the I-region of the H-2 complex. J Exp Med. 1977 Dec 1;146(6):1549-60
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory